AutismKB 2.0

Annotation Detail for TTC14


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Basic Information Top
Gene Symbol:TTC14 ( DKFZp313M1015,DRDL5813,FLJ00166,KIAA1980,PRO19630 )
Gene Full Name: tetratricopeptide repeat domain 14
Band: 3q26.33
Quick LinksEntrez ID:151613; OMIM: NA; Uniprot ID:TTC14_HUMAN; ENSEMBL ID: ENSG00000163728; HGNC ID: 24697
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body6 / 7076184
blastocyst2 / 6231932
fetus34 / 56401260
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult100 / 193912151
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor2 / 9417821
cervical tumor1 / 3436629
chondrosarcoma5 / 8282360
colorectal tumor3 / 11424626
esophageal tumor1 / 1729057
gastrointestinal tumor5 / 11936941
germ cell tumor14 / 26384553
glioma1 / 1068839
head and neck tumor5 / 13630236
kidney tumor2 / 6895929
leukemia7 / 9584273
liver tumor4 / 9635941
lung tumor3 / 10312729
lymphoma1 / 7175513
non-neoplasia1 / 9725010
normal172 / 336030751
ovarian tumor6 / 7668278
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer3 / 10268029
retinoblastoma0 / 463560 
skin tumor1 / 1249498
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor5 / 9025755
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland1 / 3319730
ascites3 / 4001574
bladder0 / 297570 
blood2 / 12347816
bone2 / 7165527
bone marrow1 / 4880120
brain54 / 110098949
cervix1 / 4817120
connective tissue4 / 14925526
ear4 / 16212246
embryonic tissue17 / 21572278
esophagus1 / 2020949
eye4 / 21105418
heart3 / 8962633
intestine7 / 23447229
kidney4 / 21177718
larynx0 / 241450 
liver11 / 20774352
lung12 / 33697435
lymph0 / 442700 
lymph node11 / 91610120
mammary gland10 / 15327165
mouth6 / 6705289
muscle12 / 107715111
nerve1 / 1576863
ovary7 / 10205168
pancreas5 / 21481223
parathyroid2 / 2053997
pharynx3 / 4132872
pituitary gland2 / 16585120
placenta10 / 28082535
prostate5 / 18934526
salivary gland0 / 201550 
skin3 / 21057414
spleen0 / 539520 
stomach2 / 9661920
testis21 / 33044263
thymus3 / 8113136
thyroid1 / 4747321
tonsil0 / 169990 
trachea3 / 5241357
umbilical cord0 / 136800 
uterus10 / 23287842
vascular5 / 5178096
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_6668_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala8.92 ± 0.33
Basal Forebrain8.7 ± 0.21
Basal Part of Pons8.39 ± 0.31
Cerebellar Cortex8.48 ± 0.32
Cerebellar Nuclei8.39 ± 0.27
Claustrum8.8 ± 0.27
Epithalamus8.87 ± 0.21
Frontal Lobe8.45 ± 0.34
Globus Pallidus9.01 ± 0.18
Hypothalamus8.39 ± 0.26
Insula8.42 ± 0.38
Limbic Lobe8.83 ± 0.44
Mesencephalon8.65 ± 0.32
Myelencephalon8.61 ± 0.4
Occipital Lobe9.07 ± 0.41
Parietal Lobe8.69 ± 0.31
Pontine Tegmentum8.63 ± 0.33
Striatum8.85 ± 0.34
Subthalamus8.27 ± 0.06
Temporal Lobe8.59 ± 0.34
Thalamus8.49 ± 0.25
White Matter9.59 ± 0.37
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Ttc14CBCerebellum13.44
18.4
Ttc14CTXCerebral cortex73.87
59.89
Ttc14HIPHippocampal region93.7
100
Ttc14HPFHippocampal formation83.95
100
Ttc14HYHypothalamus40.69
30.88
Ttc14LSXLateral septal complex66.92
44.47
Ttc14MBMidbrain28.03
26.17
Ttc14MYMedulla19.61
20.07
Ttc14OLFOlfactory bulb64.48
59.15
Ttc14PPons26.53
29.55
Ttc14PALPallidum43
36.51
Ttc14RHPRetrohippocampal region58.72
53.99
Ttc14sAMYStriatum-like amygdalar nuclei89.44
76.66
Ttc14STRStriatum39.86
30.59
Ttc14STRdStriatum dorsal region24.6
18.08
Ttc14STRvStriatum ventral region47.69
37.43
Ttc14THThalamus73.51
66.64
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018