AutismKB 2.0

Annotation Detail for PYDC2


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Basic Information Top
Gene Symbol:PYDC2 ( POP2,cPOP2 )
Gene Full Name: pyrin domain containing 2
Band: 3q28
Quick LinksEntrez ID:152138; OMIM: NA; Uniprot ID:PYDC2_HUMAN; ENSEMBL ID: ; HGNC ID: 33512
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_1307_PI416573500
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.46 ± 0.93
Basal Forebrain2.92 ± 0.33
Basal Part of Pons2.64 ± 0.36
Cerebellar Cortex2.59 ± 0.71
Cerebellar Nuclei3.18 ± 0.66
Claustrum3.51 ± 0.59
Epithalamus2.69 ± 0.89
Frontal Lobe2.69 ± 0.82
Globus Pallidus2.76 ± 0.49
Hypothalamus3 ± 0.69
Insula3.27 ± 0.85
Limbic Lobe3.01 ± 0.7
Mesencephalon3.08 ± 0.71
Myelencephalon3.02 ± 0.7
Occipital Lobe3.18 ± 0.87
Parietal Lobe3.2 ± 0.65
Pontine Tegmentum3.12 ± 0.78
Striatum2.9 ± 0.81
Subthalamus3.08 ± 0.7
Temporal Lobe3.35 ± 0.62
Thalamus2.86 ± 0.67
White Matter2.58 ± 0.5
Mouse Brain ISH
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018