AutismKB 2.0

Annotation Detail for NFXL1


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Basic Information Top
Gene Symbol:NFXL1 ( FLJ16294,HOZFP,URCC5 )
Gene Full Name: nuclear transcription factor, X-box binding-like 1
Band: 4p12
Quick LinksEntrez ID:152518; OMIM: NA; Uniprot ID:NFXL1_HUMAN; ENSEMBL ID: ENSG00000170448; HGNC ID: 18726
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst1 / 6231916
fetus9 / 56401215
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult24 / 193912112
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma1 / 1747557
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor3 / 26384511
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor1 / 6895914
leukemia4 / 9584241
liver tumor1 / 9635910
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal35 / 336030710
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer5 / 10268048
retinoblastoma1 / 4635621
skin tumor3 / 12494924
soft tissue/muscle tissue tumor5 / 12519139
uterine tumor4 / 9025744
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites0 / 400150 
bladder0 / 297570 
blood1 / 1234788
bone1 / 7165513
bone marrow4 / 4880181
brain9 / 11009898
cervix0 / 481710 
connective tissue4 / 14925526
ear1 / 1621261
embryonic tissue2 / 2157229
esophagus0 / 202090 
eye3 / 21105414
heart2 / 8962622
intestine1 / 2344724
kidney2 / 2117779
larynx0 / 241450 
liver1 / 2077434
lung4 / 33697411
lymph0 / 442700 
lymph node0 / 916100 
mammary gland4 / 15327126
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary1 / 1020519
pancreas1 / 2148124
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta2 / 2808257
prostate5 / 18934526
salivary gland0 / 201550 
skin3 / 21057414
spleen0 / 539520 
stomach0 / 966190 
testis15 / 33044245
thymus1 / 8113112
thyroid0 / 474730 
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus5 / 23287821
vascular2 / 5178038
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_8308_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.16 ± 0.26
Basal Forebrain7.1 ± 0.16
Basal Part of Pons7.06 ± 0.27
Cerebellar Cortex7.33 ± 0.19
Cerebellar Nuclei6.94 ± 0.32
Claustrum7.28 ± 0.41
Epithalamus7.34 ± 0.11
Frontal Lobe7 ± 0.28
Globus Pallidus6.92 ± 0.17
Hypothalamus7 ± 0.32
Insula7 ± 0.27
Limbic Lobe7.17 ± 0.32
Mesencephalon7.08 ± 0.37
Myelencephalon7.07 ± 0.27
Occipital Lobe7.35 ± 0.35
Parietal Lobe7.11 ± 0.24
Pontine Tegmentum6.99 ± 0.23
Striatum6.99 ± 0.28
Subthalamus7.17 ± 0.08
Temporal Lobe7.01 ± 0.31
Thalamus6.96 ± 0.19
White Matter7.16 ± 0.19
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Nfxl1CBCerebellum26.36
24.12
Nfxl1CTXCerebral cortex54.42
42.29
Nfxl1HIPHippocampal region57.04
65.93
Nfxl1HPFHippocampal formation55.4
54.08
Nfxl1HYHypothalamus34.25
20.32
Nfxl1LSXLateral septal complex35.42
18.04
Nfxl1MBMidbrain22.92
14.71
Nfxl1MYMedulla40.42
30.65
Nfxl1OLFOlfactory bulb91.39
70.95
Nfxl1PPons31.18
20.58
Nfxl1PALPallidum30.91
19.99
Nfxl1RHPRetrohippocampal region50.66
39.2
Nfxl1sAMYStriatum-like amygdalar nuclei51.39
34.05
Nfxl1STRStriatum46.49
28.88
Nfxl1STRdStriatum dorsal region44.83
28.51
Nfxl1STRvStriatum ventral region51.19
28.89
Nfxl1THThalamus20.97
13.95
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00042329 13 457 469 RMPCHKPYLCETK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018