AutismKB 2.0

Annotation Detail for CNKSR3


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Basic Information Top
Gene Symbol:CNKSR3 ( FLJ31349,MAGI1 )
Gene Full Name: CNKSR family member 3
Band: 6q25.2
Quick LinksEntrez ID:154043; OMIM: NA; Uniprot ID:CNKR3_HUMAN; ENSEMBL ID: ENSG00000153721; HGNC ID: 23034
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst1 / 6231916
fetus14 / 56401224
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult34 / 193912117
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor2 / 9417821
cervical tumor0 / 343660 
chondrosarcoma5 / 8282360
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor1 / 2638453
glioma1 / 1068839
head and neck tumor1 / 1363027
kidney tumor2 / 6895929
leukemia0 / 958420 
liver tumor1 / 9635910
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia2 / 9725020
normal60 / 336030717
ovarian tumor0 / 766820 
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor3 / 12494924
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood1 / 1234788
bone2 / 7165527
bone marrow0 / 488010 
brain13 / 110098911
cervix0 / 481710 
connective tissue5 / 14925533
ear1 / 1621261
embryonic tissue5 / 21572223
esophagus0 / 202090 
eye7 / 21105433
heart0 / 896260 
intestine1 / 2344724
kidney7 / 21177733
larynx0 / 241450 
liver4 / 20774319
lung11 / 33697432
lymph0 / 442700 
lymph node0 / 916100 
mammary gland5 / 15327132
mouth1 / 6705214
muscle0 / 1077150 
nerve0 / 157680 
ovary1 / 1020519
pancreas2 / 2148129
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate1 / 1893455
salivary gland0 / 201550 
skin4 / 21057418
spleen0 / 539520 
stomach0 / 966190 
testis9 / 33044227
thymus0 / 811310 
thyroid1 / 4747321
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus2 / 2328788
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P66592
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.11 ± 0.88
Basal Forebrain3.36 ± 0.53
Basal Part of Pons3.27 ± 0.52
Cerebellar Cortex3.01 ± 0.74
Cerebellar Nuclei3.61 ± 0.75
Claustrum3.62 ± 0.85
Epithalamus3.55 ± 0.54
Frontal Lobe3.53 ± 0.87
Globus Pallidus4.65 ± 0.45
Hypothalamus3.11 ± 0.55
Insula3.03 ± 0.69
Limbic Lobe3.06 ± 0.81
Mesencephalon3.47 ± 0.76
Myelencephalon3.67 ± 0.77
Occipital Lobe3.63 ± 0.86
Parietal Lobe3.59 ± 0.91
Pontine Tegmentum3.79 ± 0.87
Striatum4.48 ± 0.62
Subthalamus2.98 ± 0.34
Temporal Lobe3.18 ± 0.77
Thalamus4.79 ± 0.56
White Matter6.08 ± 0.49
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Cnksr3CBCerebellum85.51
100
Cnksr3CTXCerebral cortex3.92
4.02
Cnksr3HIPHippocampal region3.12
4.03
Cnksr3HPFHippocampal formation3.12
3.48
Cnksr3HYHypothalamus3.66
3.74
Cnksr3LSXLateral septal complex3.25
3.95
Cnksr3MBMidbrain3.22
4.06
Cnksr3MYMedulla6.5
9.35
Cnksr3OLFOlfactory bulb8.02
7.67
Cnksr3PPons3.87
4.89
Cnksr3PALPallidum4.25
4.64
Cnksr3RHPRetrohippocampal region3.12
2.77
Cnksr3sAMYStriatum-like amygdalar nuclei1.56
1.86
Cnksr3STRStriatum3.71
4.12
Cnksr3STRdStriatum dorsal region3.82
4.68
Cnksr3STRvStriatum ventral region4.49
3.45
Cnksr3THThalamus50.54
47.46
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018