AutismKB 2.0

Annotation Detail for NKAIN2


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Basic Information Top
Gene Symbol:NKAIN2 ( FAM77B,MGC41924,NKAIP2,TCBA,TCBA1 )
Gene Full Name: Na+/K+ transporting ATPase interacting 2
Band: 6q22.31
Quick LinksEntrez ID:154215; OMIM: 609758; Uniprot ID:NKAI2_HUMAN; ENSEMBL ID: ENSG00000188580; HGNC ID: 16443
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus59 / 564012104
neonate1 / 3109732
infant0 / 236200 
juvenile1 / 5555617
adult27 / 193912113
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor0 / 2638450 
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor3 / 6895943
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia6 / 9725061
normal98 / 336030729
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor13 / 125191103
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood2 / 12347816
bone0 / 716550 
bone marrow0 / 488010 
brain105 / 110098995
cervix0 / 481710 
connective tissue13 / 14925587
ear0 / 162120 
embryonic tissue1 / 2157224
esophagus0 / 202090 
eye1 / 2110544
heart0 / 896260 
intestine0 / 2344720 
kidney3 / 21177714
larynx0 / 241450 
liver0 / 2077430 
lung0 / 3369740 
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle0 / 1077150 
nerve1 / 1576863
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate0 / 1893450 
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach0 / 966190 
testis0 / 3304420 
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P170213
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.85 ± 0.81
Basal Forebrain4.99 ± 0.55
Basal Part of Pons5.46 ± 0.46
Cerebellar Cortex5.06 ± 0.48
Cerebellar Nuclei5.19 ± 0.6
Claustrum4.87 ± 1.02
Epithalamus4.97 ± 0.94
Frontal Lobe5.42 ± 0.51
Globus Pallidus5.81 ± 0.42
Hypothalamus4.5 ± 0.69
Insula5.32 ± 0.5
Limbic Lobe5.35 ± 0.58
Mesencephalon5.12 ± 0.74
Myelencephalon5.15 ± 0.71
Occipital Lobe4.47 ± 0.65
Parietal Lobe4.95 ± 0.55
Pontine Tegmentum5.23 ± 0.65
Striatum4.55 ± 0.72
Subthalamus5.34 ± 0.26
Temporal Lobe5.42 ± 0.51
Thalamus5.03 ± 0.71
White Matter7.45 ± 0.42
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Tcba1CBCerebellum0.7
1.09
Tcba1CTXCerebral cortex0.67
0.71
Tcba1HIPHippocampal region0.96
1
Tcba1HPFHippocampal formation1.83
1.68
Tcba1HYHypothalamus1.35
1.52
Tcba1LSXLateral septal complex0.04
0
Tcba1MBMidbrain0.3
0.49
Tcba1MYMedulla0.86
0.89
Tcba1OLFOlfactory bulb2.16
2.19
Tcba1PPons0.43
0.5
Tcba1PALPallidum0.11
0.12
Tcba1RHPRetrohippocampal region3.45
2.74
Tcba1sAMYStriatum-like amygdalar nuclei0.38
0.52
Tcba1STRStriatum0.26
0.34
Tcba1STRdStriatum dorsal region0.25
0.33
Tcba1STRvStriatum ventral region0.18
0.14
Tcba1THThalamus0.44
0.63
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018