AutismKB 2.0

Annotation Detail for AMOT


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Basic Information Top
Gene Symbol:AMOT ( KIAA1071 )
Gene Full Name: angiomotin
Band: Xq23
Quick LinksEntrez ID:154796; OMIM: 300410; Uniprot ID:AMOT_HUMAN; ENSEMBL ID: ENSG00000126016; HGNC ID: 17810
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body5 / 7076170
blastocyst0 / 623190 
fetus30 / 56401253
neonate0 / 310970 
infant1 / 2362042
juvenile0 / 555560 
adult65 / 193912133
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor4 / 9417842
cervical tumor0 / 343660 
chondrosarcoma2 / 8282324
colorectal tumor5 / 11424643
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor9 / 26384534
glioma0 / 1068830 
head and neck tumor5 / 13630236
kidney tumor6 / 6895987
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia5 / 9725051
normal100 / 336030729
ovarian tumor4 / 7668252
pancreatic tumor3 / 10461628
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer2 / 10268019
retinoblastoma0 / 463560 
skin tumor6 / 12494948
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor5 / 9025755
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain29 / 110098926
cervix0 / 481710 
connective tissue2 / 14925513
ear0 / 162120 
embryonic tissue7 / 21572232
esophagus0 / 202090 
eye0 / 2110540 
heart7 / 8962678
intestine6 / 23447225
kidney13 / 21177761
larynx0 / 241450 
liver0 / 2077430 
lung4 / 33697411
lymph0 / 442700 
lymph node1 / 9161010
mammary gland4 / 15327126
mouth6 / 6705289
muscle6 / 10771555
nerve0 / 157680 
ovary5 / 10205148
pancreas3 / 21481213
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland1 / 1658560
placenta16 / 28082556
prostate7 / 18934536
salivary gland0 / 201550 
skin6 / 21057428
spleen0 / 539520 
stomach0 / 966190 
testis8 / 33044224
thymus1 / 8113112
thyroid1 / 4747321
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus10 / 23287842
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 209521_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts6.4
Adipocyte5.4
AdrenalCortex5.65
Adrenalgland4.5
Amygdala5.75
Appendix5.55
AtrioventricularNode4.1
BDCA4+_DentriticCells6.05
Bonemarrow5.35
BronchialEpithelialCells5.35
CD105+_Endothelial5.45
CD14+_Monocytes5.8
CD19+_BCells(neg._sel.)5.85
CD33+_Myeloid7.05
CD34+6.95
CD4+_Tcells5.95
CD56+_NKCells6.5
CD71+_EarlyErythroid5
CD8+_Tcells5.3
CardiacMyocytes6.9
Caudatenucleus4.95
Cerebellum4.5
CerebellumPeduncles6.15
CiliaryGanglion4.25
CingulateCortex5.65
Colorectaladenocarcinoma5.4
DorsalRootGanglion4.15
FetalThyroid5.3
Fetalbrain5.45
Fetalliver4.7
Fetallung4.5
GlobusPallidus4.1
Heart6.85
Hypothalamus6
Kidney4.35
Leukemia_chronicMyelogenousK-5624.9
Leukemia_promyelocytic-HL-604.85
Leukemialymphoblastic(MOLT-4)4.4
Liver7.15
Lung6.05
Lymphnode4.65
Lymphoma_burkitts(Daudi)6.9
Lymphoma_burkitts(Raji)7.5
MedullaOblongata5
OccipitalLobe4.85
OlfactoryBulb4.25
Ovary3.55
Pancreas4.95
PancreaticIslet5.8
ParietalLobe5.95
Pituitary10.15
Placenta5.7
Pons6.35
PrefrontalCortex6.85
Prostate6.35
Salivarygland4.3
SkeletalMuscle7.25
Skin4.1
SmoothMuscle6.2
Spinalcord15.95
SubthalamicNucleus4.9
SuperiorCervicalGanglion12.95
TemporalLobe5.9
Testis4.8
TestisGermCell4.7
TestisIntersitial5.4
TestisLeydigCell5.4
TestisSeminiferousTubule4.7
Thalamus5.65
Thymus4.35
Thyroid6.85
Tongue5.65
Tonsil5.3
Trachea4.55
TrigeminalGanglion14.15
Uterus4.5
UterusCorpus4.9
WholeBlood5.95
Wholebrain4.7
colon5.5
pineal_day6.86
pineal_night6.62
retina6.6
small_intestine5.3
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_11710_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.01 ± 0.6
Basal Forebrain4.68 ± 0.41
Basal Part of Pons4.26 ± 0.39
Cerebellar Cortex4.09 ± 0.45
Cerebellar Nuclei4.45 ± 0.42
Claustrum4.84 ± 0.93
Epithalamus4.83 ± 0.71
Frontal Lobe4.48 ± 0.45
Globus Pallidus5.67 ± 0.43
Hypothalamus4.56 ± 0.65
Insula4.54 ± 0.31
Limbic Lobe4.59 ± 0.52
Mesencephalon4.68 ± 0.6
Myelencephalon4.67 ± 0.58
Occipital Lobe4.84 ± 0.55
Parietal Lobe4.67 ± 0.56
Pontine Tegmentum4.7 ± 0.52
Striatum5.07 ± 0.47
Subthalamus4.01 ± 0.19
Temporal Lobe4.46 ± 0.51
Thalamus4.79 ± 0.43
White Matter4.46 ± 0.33
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
AmotCBCerebellum14.84
19.86
AmotCTXCerebral cortex1.68
1.84
AmotHIPHippocampal region4.16
4.57
AmotHPFHippocampal formation3.11
3.06
AmotHYHypothalamus0.43
0.46
AmotLSXLateral septal complex0.76
0.63
AmotMBMidbrain0.86
1.29
AmotMYMedulla3.56
4.1
AmotOLFOlfactory bulb6.85
5.77
AmotPPons1.7
1.91
AmotPALPallidum1.02
1.3
AmotRHPRetrohippocampal region1.81
1.34
AmotsAMYStriatum-like amygdalar nuclei1.68
1.44
AmotSTRStriatum0.94
0.91
AmotSTRdStriatum dorsal region0.68
0.73
AmotSTRvStriatum ventral region1.17
0.86
AmotTHThalamus0.94
0.94
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00496752 20 298 317 DTTVISHSPNTSYDTALEAR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018