AutismKB 2.0

Annotation Detail for VKORC1L1


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Basic Information Top
Gene Symbol:VKORC1L1 ( DKFZp762H0113 )
Gene Full Name: vitamin K epoxide reductase complex, subunit 1-like 1
Band: 7q11.21
Quick LinksEntrez ID:154807; OMIM: 608838; Uniprot ID:VKORL_HUMAN; ENSEMBL ID: ENSG00000196715; HGNC ID: 21492
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body4 / 7076156
blastocyst2 / 6231932
fetus32 / 56401256
neonate0 / 310970 
infant0 / 236200 
juvenile2 / 5555635
adult77 / 193912139
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma2 / 17475114
breast (mammary gland) tumor2 / 9417821
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor5 / 11424643
esophageal tumor0 / 172900 
gastrointestinal tumor11 / 11936992
germ cell tumor24 / 26384590
glioma1 / 1068839
head and neck tumor1 / 1363027
kidney tumor3 / 6895943
leukemia2 / 9584220
liver tumor3 / 9635931
lung tumor4 / 10312738
lymphoma10 / 71755139
non-neoplasia1 / 9725010
normal114 / 336030733
ovarian tumor5 / 7668265
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS2 / 12568015
prostate cancer12 / 102680116
retinoblastoma5 / 46356107
skin tumor1 / 1249498
soft tissue/muscle tissue tumor8 / 12519163
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites6 / 40015149
bladder2 / 2975767
blood3 / 12347824
bone2 / 7165527
bone marrow0 / 488010 
brain25 / 110098922
cervix0 / 481710 
connective tissue7 / 14925546
ear3 / 16212185
embryonic tissue14 / 21572264
esophagus0 / 202090 
eye7 / 21105433
heart8 / 8962689
intestine11 / 23447246
kidney7 / 21177733
larynx0 / 241450 
liver5 / 20774324
lung12 / 33697435
lymph10 / 44270225
lymph node3 / 9161032
mammary gland3 / 15327119
mouth2 / 6705229
muscle5 / 10771546
nerve1 / 1576863
ovary6 / 10205158
pancreas5 / 21481223
parathyroid2 / 2053997
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta7 / 28082524
prostate16 / 18934584
salivary gland0 / 201550 
skin8 / 21057437
spleen2 / 5395237
stomach3 / 9661931
testis20 / 33044260
thymus1 / 8113112
thyroid1 / 4747321
tonsil0 / 169990 
trachea3 / 5241357
umbilical cord0 / 136800 
uterus7 / 23287830
vascular3 / 5178057
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_6927_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.52 ± 0.71
Basal Forebrain4.43 ± 0.66
Basal Part of Pons4.61 ± 0.54
Cerebellar Cortex4.96 ± 0.35
Cerebellar Nuclei4.48 ± 0.58
Claustrum4.62 ± 0.94
Epithalamus4.67 ± 0.55
Frontal Lobe4.91 ± 0.5
Globus Pallidus3.78 ± 0.58
Hypothalamus4.75 ± 0.62
Insula4.89 ± 0.44
Limbic Lobe4.59 ± 0.56
Mesencephalon4.7 ± 0.61
Myelencephalon4.65 ± 0.58
Occipital Lobe4.28 ± 0.58
Parietal Lobe4.69 ± 0.61
Pontine Tegmentum4.63 ± 0.68
Striatum4.03 ± 0.71
Subthalamus4.73 ± 0.15
Temporal Lobe4.82 ± 0.52
Thalamus4.57 ± 0.55
White Matter4.77 ± 0.64
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Vkorc1l1CBCerebellum3.74
3.58
Vkorc1l1CTXCerebral cortex4.06
1.65
Vkorc1l1HIPHippocampal region5.3
4.26
Vkorc1l1HPFHippocampal formation4.65
3.05
Vkorc1l1HYHypothalamus2.14
1.12
Vkorc1l1LSXLateral septal complex0.05
0
Vkorc1l1MBMidbrain1.46
0.78
Vkorc1l1MYMedulla6.46
5.74
Vkorc1l1OLFOlfactory bulb2.6
1.09
Vkorc1l1PPons2.23
1.07
Vkorc1l1PALPallidum2.59
1.33
Vkorc1l1RHPRetrohippocampal region3.82
1.68
Vkorc1l1sAMYStriatum-like amygdalar nuclei1.51
0.47
Vkorc1l1STRStriatum0.76
0.42
Vkorc1l1STRdStriatum dorsal region0.77
0.53
Vkorc1l1STRvStriatum ventral region0.73
0.22
Vkorc1l1THThalamus0.59
0.41
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00397184 11 69 79 GFGLLGSIFGK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018