AutismKB 2.0

Annotation Detail for AMOTL1


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Basic Information Top
Gene Symbol:AMOTL1 ( JEAP )
Gene Full Name: angiomotin like 1
Band: 11q21
Quick LinksEntrez ID:154810; OMIM: NA; Uniprot ID:AMOL1_HUMAN; ENSEMBL ID: ENSG00000166025; HGNC ID: 17811
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body8 / 70761113
blastocyst6 / 6231996
fetus24 / 56401242
neonate0 / 310970 
infant1 / 2362042
juvenile0 / 555560 
adult97 / 193912150
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor4 / 12794312
bladder carcinoma2 / 17475114
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma7 / 8282384
colorectal tumor3 / 11424626
esophageal tumor1 / 1729057
gastrointestinal tumor1 / 1193698
germ cell tumor9 / 26384534
glioma6 / 10688356
head and neck tumor10 / 13630273
kidney tumor4 / 6895958
leukemia2 / 9584220
liver tumor1 / 9635910
lung tumor3 / 10312729
lymphoma1 / 7175513
non-neoplasia7 / 9725071
normal164 / 336030748
ovarian tumor3 / 7668239
pancreatic tumor12 / 104616114
primitive neuroectodermal tumor of the CNS13 / 125680103
prostate cancer1 / 1026809
retinoblastoma1 / 4635621
skin tumor15 / 124949120
soft tissue/muscle tissue tumor8 / 12519163
uterine tumor4 / 9025744
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland4 / 33197120
ascites0 / 400150 
bladder3 / 29757100
blood1 / 1234788
bone3 / 7165541
bone marrow2 / 4880140
brain54 / 110098949
cervix0 / 481710 
connective tissue10 / 14925566
ear0 / 162120 
embryonic tissue19 / 21572288
esophagus1 / 2020949
eye5 / 21105423
heart0 / 896260 
intestine4 / 23447217
kidney8 / 21177737
larynx1 / 2414541
liver4 / 20774319
lung22 / 33697465
lymph0 / 442700 
lymph node2 / 9161021
mammary gland3 / 15327119
mouth5 / 6705274
muscle10 / 10771592
nerve0 / 157680 
ovary4 / 10205139
pancreas13 / 21481260
parathyroid0 / 205390 
pharynx3 / 4132872
pituitary gland1 / 1658560
placenta28 / 28082599
prostate20 / 189345105
salivary gland0 / 201550 
skin18 / 21057485
spleen1 / 5395218
stomach2 / 9661920
testis9 / 33044227
thymus9 / 81131110
thyroid3 / 4747363
tonsil0 / 169990 
trachea6 / 52413114
umbilical cord0 / 136800 
uterus13 / 23287855
vascular3 / 5178057
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P401768
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.3 ± 0.38
Basal Forebrain5.47 ± 0.33
Basal Part of Pons5.86 ± 0.42
Cerebellar Cortex5.53 ± 0.62
Cerebellar Nuclei5.23 ± 0.32
Claustrum5.32 ± 0.49
Epithalamus5.45 ± 0.41
Frontal Lobe5.5 ± 0.58
Globus Pallidus6.04 ± 0.36
Hypothalamus5.01 ± 0.47
Insula5.4 ± 0.51
Limbic Lobe5.36 ± 0.76
Mesencephalon5.06 ± 0.61
Myelencephalon5.54 ± 0.58
Occipital Lobe5.62 ± 0.61
Parietal Lobe5.6 ± 0.46
Pontine Tegmentum5.51 ± 0.61
Striatum4.94 ± 0.55
Subthalamus4.55 ± 0.34
Temporal Lobe5.29 ± 0.57
Thalamus6.48 ± 0.59
White Matter4.12 ± 0.65
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Amotl1CBCerebellum0.91
1.23
Amotl1CTXCerebral cortex0.89
0.87
Amotl1HIPHippocampal region4.17
5.16
Amotl1HPFHippocampal formation2.78
3.19
Amotl1HYHypothalamus5.57
4.46
Amotl1LSXLateral septal complex0.46
0.23
Amotl1MBMidbrain8.45
8.43
Amotl1MYMedulla2.83
2.63
Amotl1OLFOlfactory bulb0.68
0.84
Amotl1PPons0.95
0.84
Amotl1PALPallidum0.87
0.67
Amotl1RHPRetrohippocampal region0.65
0.67
Amotl1sAMYStriatum-like amygdalar nuclei0.99
0.74
Amotl1STRStriatum0.68
0.55
Amotl1STRdStriatum dorsal region0.64
0.55
Amotl1STRvStriatum ventral region0.51
0.33
Amotl1THThalamus67.78
64.34
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00851647 14 793 806 SVPSIAAATGTHSR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018