AutismKB 2.0

Annotation Detail for ADRB3


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Basic Information Top
Gene Symbol:ADRB3 ( BETA3AR,FLJ99960 )
Gene Full Name: adrenergic, beta-3-, receptor
Band: 8p11.23
Quick LinksEntrez ID:155; OMIM: 109691; Uniprot ID:ADRB3_HUMAN; ENSEMBL ID: ENSG00000188778; HGNC ID: 288
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus1 / 5640121
neonate0 / 310970 
infant0 / 236200 
juvenile17 / 55556305
adult11 / 19391215
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor0 / 2638450 
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal13 / 33603073
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS17 / 125680135
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain17 / 110098915
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye2 / 2110549
heart0 / 896260 
intestine0 / 2344720 
kidney0 / 2117770 
larynx0 / 241450 
liver0 / 2077430 
lung0 / 3369740 
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary3 / 10205129
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta7 / 28082524
prostate0 / 1893450 
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach0 / 966190 
testis0 / 3304420 
thymus1 / 8113112
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus1 / 2328784
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 206812_at
Cell line Expression level Expression bar
721_B_lymphoblasts5.95
Adipocyte4.7
AdrenalCortex5.4
Adrenalgland4.1
Amygdala4.95
Appendix5.35
AtrioventricularNode4.85
BDCA4+_DentriticCells5.5
Bonemarrow4.95
BronchialEpithelialCells4.65
CD105+_Endothelial5.45
CD14+_Monocytes5.4
CD19+_BCells(neg._sel.)5.15
CD33+_Myeloid6.2
CD34+5.95
CD4+_Tcells5.05
CD56+_NKCells5.8
CD71+_EarlyErythroid4.5
CD8+_Tcells4.55
CardiacMyocytes6
Caudatenucleus4.25
Cerebellum3.85
CerebellumPeduncles5.35
CiliaryGanglion3.85
CingulateCortex4.9
Colorectaladenocarcinoma4.8
DorsalRootGanglion3.8
FetalThyroid4.6
Fetalbrain4.65
Fetalliver4.2
Fetallung4
GlobusPallidus3.55
Heart6.15
Hypothalamus5.15
Kidney3.9
Leukemia_chronicMyelogenousK-5624.3
Leukemia_promyelocytic-HL-604.25
Leukemialymphoblastic(MOLT-4)3.9
Liver6.55
Lung5.25
Lymphnode4.15
Lymphoma_burkitts(Daudi)6.45
Lymphoma_burkitts(Raji)7
MedullaOblongata4.35
OccipitalLobe4.3
OlfactoryBulb3.8
Ovary3.45
Pancreas3.9
PancreaticIslet5.05
ParietalLobe5.15
Pituitary5.65
Placenta4.85
Pons4.5
PrefrontalCortex5.9
Prostate5.55
Salivarygland4
SkeletalMuscle6.75
Skin4.15
SmoothMuscle5.35
Spinalcord5.05
SubthalamicNucleus4.35
SuperiorCervicalGanglion6.95
TemporalLobe4.4
Testis4.1
TestisGermCell3.95
TestisIntersitial3.95
TestisLeydigCell4.9
TestisSeminiferousTubule4.1
Thalamus4.8
Thymus3.75
Thyroid5.8
Tongue4.6
Tonsil4.65
Trachea4
TrigeminalGanglion5
Uterus3.95
UterusCorpus4.4
WholeBlood5.2
Wholebrain4
colon4.8
pineal_day7.4
pineal_night6.04
retina5.775
small_intestine4.6
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_16253_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.76 ± 1.01
Basal Forebrain2.4 ± 0.36
Basal Part of Pons2.16 ± 0.8
Cerebellar Cortex2.36 ± 0.86
Cerebellar Nuclei2.52 ± 0.62
Claustrum3.09 ± 1.03
Epithalamus2.37 ± 0.8
Frontal Lobe2.29 ± 0.71
Globus Pallidus2.63 ± 0.6
Hypothalamus2.51 ± 0.91
Insula2.15 ± 0.66
Limbic Lobe2.53 ± 0.67
Mesencephalon2.6 ± 0.8
Myelencephalon2.44 ± 0.66
Occipital Lobe2.51 ± 0.86
Parietal Lobe2.53 ± 0.66
Pontine Tegmentum2.37 ± 0.63
Striatum2.48 ± 0.72
Subthalamus2.52 ± 0.65
Temporal Lobe2.34 ± 0.72
Thalamus2.36 ± 0.69
White Matter2.43 ± 0.19
Mouse Brain ISH
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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