AutismKB 2.0

Annotation Detail for GIMAP8


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Basic Information Top
Gene Symbol:GIMAP8 ( DKFZp667I133,IANT,MGC129545,hIAN6 )
Gene Full Name: GTPase, IMAP family member 8
Band: 7q36.1
Quick LinksEntrez ID:155038; OMIM: NA; Uniprot ID:GIMA8_HUMAN; ENSEMBL ID: ENSG00000171115; HGNC ID: 21792
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus1 / 5640121
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult26 / 193912113
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor4 / 26384515
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor1 / 6895914
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia5 / 9725051
normal40 / 336030711
ovarian tumor0 / 766820 
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue2 / 13106152
adrenal gland1 / 3319730
ascites0 / 400150 
bladder1 / 2975733
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain14 / 110098912
cervix0 / 481710 
connective tissue3 / 14925520
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye2 / 2110549
heart0 / 896260 
intestine0 / 2344720 
kidney2 / 2117779
larynx0 / 241450 
liver0 / 2077430 
lung1 / 3369742
lymph0 / 442700 
lymph node1 / 9161010
mammary gland1 / 1532716
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary1 / 1020519
pancreas1 / 2148124
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta5 / 28082517
prostate1 / 1893455
salivary gland0 / 201550 
skin0 / 2105740 
spleen4 / 5395274
stomach0 / 966190 
testis0 / 3304420 
thymus0 / 811310 
thyroid1 / 4747321
tonsil0 / 169990 
trachea8 / 52413152
umbilical cord0 / 136800 
uterus13 / 23287855
vascular2 / 5178038
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P132383
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.1 ± 0.92
Basal Forebrain2.96 ± 0.62
Basal Part of Pons3.26 ± 0.79
Cerebellar Cortex2.58 ± 0.5
Cerebellar Nuclei4.05 ± 0.75
Claustrum3.19 ± 0.55
Epithalamus2.96 ± 0.84
Frontal Lobe3.03 ± 0.73
Globus Pallidus4.23 ± 0.45
Hypothalamus2.99 ± 0.67
Insula3.25 ± 0.47
Limbic Lobe2.83 ± 0.73
Mesencephalon3.14 ± 0.73
Myelencephalon3.15 ± 0.62
Occipital Lobe3.1 ± 0.77
Parietal Lobe2.85 ± 0.77
Pontine Tegmentum3.06 ± 0.74
Striatum3.91 ± 0.48
Subthalamus3.67 ± 0.59
Temporal Lobe3.02 ± 0.62
Thalamus3.3 ± 0.59
White Matter3.59 ± 0.91
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Gimap8CBCerebellum0.62
0.56
Gimap8CTXCerebral cortex3.17
1.11
Gimap8HIPHippocampal region0.42
0.18
Gimap8HPFHippocampal formation3.41
1.43
Gimap8HYHypothalamus0.64
0.61
Gimap8LSXLateral septal complex0.09
0.09
Gimap8MBMidbrain0.32
0.23
Gimap8MYMedulla2.35
1.59
Gimap8OLFOlfactory bulb4.08
2.74
Gimap8PPons0.99
0.71
Gimap8PALPallidum0.21
0.14
Gimap8RHPRetrohippocampal region8.78
3.33
Gimap8sAMYStriatum-like amygdalar nuclei0.34
0.2
Gimap8STRStriatum0.2
0.11
Gimap8STRdStriatum dorsal region0.1
0.05
Gimap8STRvStriatum ventral region0.61
0.31
Gimap8THThalamus0.18
0.12
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018