AutismKB 2.0

Annotation Detail for ZNF425


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Basic Information Top
Gene Symbol:ZNF425 ( MGC150568 )
Gene Full Name: zinc finger protein 425
Band: 7q36.1
Quick LinksEntrez ID:155054; OMIM: NA; Uniprot ID:ZN425_HUMAN; ENSEMBL ID: ENSG00000204947; HGNC ID: 20690
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst3 / 6231948
fetus12 / 56401221
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult27 / 193912113
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor13 / 26384549
glioma1 / 1068839
head and neck tumor1 / 1363027
kidney tumor1 / 6895914
leukemia2 / 9584220
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma1 / 7175513
non-neoplasia2 / 9725020
normal39 / 336030711
ovarian tumor2 / 7668226
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS5 / 12568039
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor2 / 12494916
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites1 / 4001524
bladder0 / 297570 
blood1 / 1234788
bone2 / 7165527
bone marrow0 / 488010 
brain15 / 110098913
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue6 / 21572227
esophagus0 / 202090 
eye6 / 21105428
heart2 / 8962622
intestine2 / 2344728
kidney3 / 21177714
larynx0 / 241450 
liver0 / 2077430 
lung4 / 33697411
lymph1 / 4427022
lymph node0 / 916100 
mammary gland1 / 1532716
mouth1 / 6705214
muscle1 / 1077159
nerve0 / 157680 
ovary3 / 10205129
pancreas0 / 2148120 
parathyroid3 / 20539146
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta3 / 28082510
prostate0 / 1893450 
salivary gland0 / 201550 
skin2 / 2105749
spleen0 / 539520 
stomach0 / 966190 
testis9 / 33044227
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus1 / 2328784
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_1453_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.58 ± 0.28
Basal Forebrain5.37 ± 0.3
Basal Part of Pons5.37 ± 0.27
Cerebellar Cortex5.65 ± 0.28
Cerebellar Nuclei5.3 ± 0.44
Claustrum5.59 ± 0.53
Epithalamus5.42 ± 0.52
Frontal Lobe5.3 ± 0.37
Globus Pallidus5.31 ± 0.38
Hypothalamus5.3 ± 0.39
Insula5.39 ± 0.41
Limbic Lobe5.5 ± 0.38
Mesencephalon5.48 ± 0.36
Myelencephalon5.41 ± 0.4
Occipital Lobe5.63 ± 0.37
Parietal Lobe5.52 ± 0.3
Pontine Tegmentum5.47 ± 0.41
Striatum5.23 ± 0.32
Subthalamus5.07 ± 0.57
Temporal Lobe5.44 ± 0.34
Thalamus5.39 ± 0.27
White Matter5.76 ± 0.14
Mouse Brain ISH
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018