AutismKB 2.0

Annotation Detail for CYP3A7


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Basic Information Top
Gene Symbol:CYP3A7 ( CP37,P450-HFLA )
Gene Full Name: cytochrome P450, family 3, subfamily A, polypeptide 7
Band: 7q22.1
Quick LinksEntrez ID:1551; OMIM: 605340; Uniprot ID:CP3A7_HUMAN; ENSEMBL ID: ENSG00000160870; HGNC ID: 2640
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus48 / 56401285
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult223 / 1939121115
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor4 / 11936933
germ cell tumor1 / 2638453
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia2 / 9584220
liver tumor51 / 96359529
lung tumor0 / 1031270 
lymphoma1 / 7175513
non-neoplasia0 / 972500 
normal265 / 336030778
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor93 / 125191742
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland3 / 3319790
ascites0 / 400150 
bladder0 / 297570 
blood2 / 12347816
bone0 / 716550 
bone marrow0 / 488010 
brain3 / 11009892
cervix0 / 481710 
connective tissue93 / 149255623
ear0 / 162120 
embryonic tissue3 / 21572213
esophagus0 / 202090 
eye0 / 2110540 
heart3 / 8962633
intestine12 / 23447251
kidney7 / 21177733
larynx0 / 241450 
liver240 / 2077431155
lung0 / 3369740 
lymph0 / 442700 
lymph node0 / 916100 
mammary gland17 / 153271110
mouth2 / 6705229
muscle1 / 1077159
nerve0 / 157680 
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta1 / 2808253
prostate0 / 1893450 
salivary gland0 / 201550 
skin0 / 2105740 
spleen1 / 5395218
stomach4 / 9661941
testis0 / 3304420 
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 205939_at
Cell line Expression level Expression bar
721_B_lymphoblasts5.05
Adipocyte4.05
AdrenalCortex4.45
Adrenalgland3.45
Amygdala4.3
Appendix5.05
AtrioventricularNode4.75
BDCA4+_DentriticCells4.45
Bonemarrow4.15
BronchialEpithelialCells4
CD105+_Endothelial4.15
CD14+_Monocytes4.45
CD19+_BCells(neg._sel.)4.35
CD33+_Myeloid5.25
CD34+5.15
CD4+_Tcells4.4
CD56+_NKCells4.9
CD71+_EarlyErythroid4
CD8+_Tcells3.85
CardiacMyocytes5.25
Caudatenucleus3.7
Cerebellum3.3
CerebellumPeduncles4.65
CiliaryGanglion4.65
CingulateCortex4.2
Colorectaladenocarcinoma4.05
DorsalRootGanglion7.05
FetalThyroid4.05
Fetalbrain4.05
Fetalliver4837.2
Fetallung94.35
GlobusPallidus3.05
Heart5.2
Hypothalamus4.45
Kidney3.75
Leukemia_chronicMyelogenousK-5623.7
Leukemia_promyelocytic-HL-603.6
Leukemialymphoblastic(MOLT-4)3.25
Liver8.2
Lung4.5
Lymphnode3.5
Lymphoma_burkitts(Daudi)5.25
Lymphoma_burkitts(Raji)5.95
MedullaOblongata3.75
OccipitalLobe3.7
OlfactoryBulb3.2
Ovary3.25
Pancreas3.3
PancreaticIslet4.35
ParietalLobe4.4
Pituitary4.95
Placenta4.25
Pons3.9
PrefrontalCortex5.05
Prostate4.75
Salivarygland3.85
SkeletalMuscle5.2
Skin5
SmoothMuscle4.65
Spinalcord5.8
SubthalamicNucleus3.75
SuperiorCervicalGanglion5.35
TemporalLobe4
Testis3.55
TestisGermCell3.4
TestisIntersitial3.7
TestisLeydigCell4.45
TestisSeminiferousTubule3.55
Thalamus4.1
Thymus3.25
Thyroid5.15
Tongue4.15
Tonsil4.1
Trachea3.4
TrigeminalGanglion5.65
Uterus3.4
UterusCorpus4.05
WholeBlood4.5
Wholebrain3.4
colon4.05
pineal_day5.12
pineal_night5
retina4.975
small_intestine3.95
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_15814_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.69 ± 1.02
Basal Forebrain2.29 ± 0.35
Basal Part of Pons2.95 ± 0.4
Cerebellar Cortex2.18 ± 0.88
Cerebellar Nuclei2.79 ± 1.01
Claustrum3.17 ± 0.86
Epithalamus3.34 ± 1
Frontal Lobe2.29 ± 0.76
Globus Pallidus2.7 ± 0.33
Hypothalamus2.35 ± 0.62
Insula2.29 ± 0.84
Limbic Lobe2.34 ± 0.69
Mesencephalon2.4 ± 0.73
Myelencephalon2.41 ± 0.71
Occipital Lobe2.31 ± 0.64
Parietal Lobe2.47 ± 0.71
Pontine Tegmentum2.43 ± 0.85
Striatum2.46 ± 0.73
Subthalamus2.52 ± 0.76
Temporal Lobe2.3 ± 0.71
Thalamus2.29 ± 0.6
White Matter2.83 ± 0.59
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Cyp3a13CBCerebellum0.44
0.77
Cyp3a13CTXCerebral cortex0.27
0.48
Cyp3a13HIPHippocampal region0.2
0.4
Cyp3a13HPFHippocampal formation0.16
0.28
Cyp3a13HYHypothalamus0.01
0.02
Cyp3a13LSXLateral septal complex0
0
Cyp3a13MBMidbrain0.15
0.26
Cyp3a13MYMedulla0.19
0.27
Cyp3a13OLFOlfactory bulb0.47
1.49
Cyp3a13PPons0.15
0.21
Cyp3a13PALPallidum0.04
0.04
Cyp3a13RHPRetrohippocampal region0.09
0.09
Cyp3a13sAMYStriatum-like amygdalar nuclei0.08
0.14
Cyp3a13STRStriatum0.24
0.34
Cyp3a13STRdStriatum dorsal region0.06
0.06
Cyp3a13STRvStriatum ventral region1.1
1.42
Cyp3a13THThalamus0.09
0.16
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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