AutismKB 2.0

Annotation Detail for CYP2E1


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:CYP2E1 ( CPE1,CYP2E,P450-J,P450C2E )
Gene Full Name: cytochrome P450, family 2, subfamily E, polypeptide 1
Band: 10q26.3
Quick LinksEntrez ID:1571; OMIM: 124040; Uniprot ID:CP2E1_HUMAN; ENSEMBL ID: ENSG00000130649; HGNC ID: 2631
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus27 / 56401247
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult132 / 193912168
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor1 / 2638453
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia6 / 9584262
liver tumor30 / 96359311
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal178 / 336030752
ovarian tumor3 / 7668239
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood6 / 12347848
bone1 / 7165513
bone marrow0 / 488010 
brain20 / 110098918
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye0 / 2110540 
heart0 / 896260 
intestine0 / 2344720 
kidney0 / 2117770 
larynx0 / 241450 
liver174 / 207743837
lung10 / 33697429
lymph0 / 442700 
lymph node0 / 916100 
mammary gland4 / 15327126
mouth0 / 670520 
muscle1 / 1077159
nerve0 / 157680 
ovary3 / 10205129
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate1 / 1893455
salivary gland0 / 201550 
skin1 / 2105744
spleen0 / 539520 
stomach0 / 966190 
testis3 / 3304429
thymus1 / 8113112
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus1 / 2328784
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 209976_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts6.05
Adipocyte5.3
AdrenalCortex5.8
Adrenalgland4.6
Amygdala5.55
Appendix5.75
AtrioventricularNode4.4
BDCA4+_DentriticCells5.3
Bonemarrow5.6
BronchialEpithelialCells5
CD105+_Endothelial5.1
CD14+_Monocytes5.55
CD19+_BCells(neg._sel.)5.35
CD33+_Myeloid6.55
CD34+6.55
CD4+_Tcells5.65
CD56+_NKCells5.85
CD71+_EarlyErythroid5
CD8+_Tcells5.15
CardiacMyocytes7.35
Caudatenucleus4.8
Cerebellum4.45
CerebellumPeduncles6.65
CiliaryGanglion3.95
CingulateCortex5.75
Colorectaladenocarcinoma5.25
DorsalRootGanglion4.3
FetalThyroid6.2
Fetalbrain5.25
Fetalliver4.9
Fetallung4.35
GlobusPallidus4.05
Heart8.3
Hypothalamus5.6
Kidney4.95
Leukemia_chronicMyelogenousK-5624.8
Leukemia_promyelocytic-HL-604.7
Leukemialymphoblastic(MOLT-4)4.2
Liver10794.6
Lung5.7
Lymphnode4.5
Lymphoma_burkitts(Daudi)6.9
Lymphoma_burkitts(Raji)8.95
MedullaOblongata6.1
OccipitalLobe4.85
OlfactoryBulb4.2
Ovary3.6
Pancreas4.35
PancreaticIslet5.7
ParietalLobe6.3
Pituitary6.25
Placenta5.4
Pons5.15
PrefrontalCortex6.6
Prostate6.25
Salivarygland4.3
SkeletalMuscle8.6
Skin4.35
SmoothMuscle5.95
Spinalcord6.05
SubthalamicNucleus5
SuperiorCervicalGanglion9.1
TemporalLobe5.05
Testis4.6
TestisGermCell4.35
TestisIntersitial4.5
TestisLeydigCell5.45
TestisSeminiferousTubule4.6
Thalamus5.55
Thymus4.1
Thyroid6.45
Tongue5.5
Tonsil5.3
Trachea4.45
TrigeminalGanglion5.6
Uterus4.35
UterusCorpus5.15
WholeBlood5.7
Wholebrain4.5
colon5.4
pineal_day6.48
pineal_night6.36
retina6.425
small_intestine5.15
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P394940
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.22 ± 0.67
Basal Forebrain3.27 ± 0.41
Basal Part of Pons3.55 ± 0.27
Cerebellar Cortex3.94 ± 0.5
Cerebellar Nuclei3.85 ± 0.37
Claustrum4.18 ± 0.55
Epithalamus3.5 ± 0.87
Frontal Lobe3.89 ± 0.56
Globus Pallidus3.4 ± 0.74
Hypothalamus3.91 ± 0.29
Insula3.87 ± 0.59
Limbic Lobe4 ± 0.7
Mesencephalon3.99 ± 0.57
Myelencephalon3.91 ± 0.6
Occipital Lobe4.22 ± 0.39
Parietal Lobe4.11 ± 0.58
Pontine Tegmentum4 ± 0.75
Striatum3.63 ± 0.86
Subthalamus4.27 ± 1.06
Temporal Lobe3.95 ± 0.59
Thalamus3.86 ± 0.53
White Matter3.03 ± 0.36
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Cyp2e1CBCerebellum1.27
1.53
Cyp2e1CTXCerebral cortex1.09
1.05
Cyp2e1HIPHippocampal region1.87
2.34
Cyp2e1HPFHippocampal formation1.76
2.05
Cyp2e1HYHypothalamus1.72
1.21
Cyp2e1LSXLateral septal complex0
0
Cyp2e1MBMidbrain0.74
0.72
Cyp2e1MYMedulla2.53
3.1
Cyp2e1OLFOlfactory bulb2.94
3.32
Cyp2e1PPons2.32
3.32
Cyp2e1PALPallidum0.54
0.37
Cyp2e1RHPRetrohippocampal region1.31
1.11
Cyp2e1sAMYStriatum-like amygdalar nuclei0.85
0.66
Cyp2e1STRStriatum0.6
0.46
Cyp2e1STRdStriatum dorsal region0.43
0.39
Cyp2e1STRvStriatum ventral region1.17
0.67
Cyp2e1THThalamus1.51
1.2
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved