AutismKB 2.0

Annotation Detail for TMEM65


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Basic Information Top
Gene Symbol:TMEM65 ( - )
Gene Full Name: transmembrane protein 65
Band: 8q24.13
Quick LinksEntrez ID:157378; OMIM: NA; Uniprot ID:TMM65_HUMAN; ENSEMBL ID: ENSG00000164983; HGNC ID: 25203
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus14 / 56401224
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult31 / 193912115
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor2 / 11424617
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor2 / 2638457
glioma1 / 1068839
head and neck tumor1 / 1363027
kidney tumor1 / 6895914
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor2 / 10312719
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal53 / 336030715
ovarian tumor2 / 7668226
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer1 / 1026809
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder1 / 2975733
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain19 / 110098917
cervix0 / 481710 
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye3 / 21105414
heart1 / 8962611
intestine3 / 23447212
kidney6 / 21177728
larynx0 / 241450 
liver2 / 2077439
lung3 / 3369748
lymph0 / 442700 
lymph node0 / 916100 
mammary gland1 / 1532716
mouth1 / 6705214
muscle3 / 10771527
nerve0 / 157680 
ovary2 / 10205119
pancreas6 / 21481227
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta8 / 28082528
prostate3 / 18934515
salivary gland0 / 201550 
skin0 / 2105740 
spleen2 / 5395237
stomach0 / 966190 
testis1 / 3304423
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_602_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala8.29 ± 0.26
Basal Forebrain8.35 ± 0.25
Basal Part of Pons8.5 ± 0.21
Cerebellar Cortex8.4 ± 0.2
Cerebellar Nuclei8.32 ± 0.34
Claustrum8.46 ± 0.38
Epithalamus8.28 ± 0.35
Frontal Lobe8.65 ± 0.34
Globus Pallidus8.2 ± 0.39
Hypothalamus8.66 ± 0.25
Insula8.54 ± 0.34
Limbic Lobe8.1 ± 0.45
Mesencephalon8.31 ± 0.37
Myelencephalon8.36 ± 0.4
Occipital Lobe7.89 ± 0.45
Parietal Lobe8.35 ± 0.4
Pontine Tegmentum8.38 ± 0.59
Striatum7.19 ± 0.46
Subthalamus7.93 ± 0.31
Temporal Lobe8.49 ± 0.27
Thalamus8.82 ± 0.32
White Matter8.11 ± 0.25
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Tmem65CBCerebellum22.9
34.26
Tmem65CTXCerebral cortex38.76
30.32
Tmem65HIPHippocampal region15.98
17.29
Tmem65HPFHippocampal formation21
21.2
Tmem65HYHypothalamus17.2
15.03
Tmem65LSXLateral septal complex14.58
14.43
Tmem65MBMidbrain20.55
20.69
Tmem65MYMedulla29.1
36.13
Tmem65OLFOlfactory bulb28.05
23.5
Tmem65PPons23.34
27.47
Tmem65PALPallidum31.9
36.41
Tmem65RHPRetrohippocampal region29.11
25.96
Tmem65sAMYStriatum-like amygdalar nuclei22.52
19.67
Tmem65STRStriatum10.63
10.07
Tmem65STRdStriatum dorsal region7.77
7.83
Tmem65STRvStriatum ventral region12.26
10.54
Tmem65THThalamus27.23
24.51
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018