AutismKB 2.0

Annotation Detail for FBXO16


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Basic Information Top
Gene Symbol:FBXO16 ( FBX16,MGC125923,MGC125924,MGC125925 )
Gene Full Name: F-box protein 16
Band: 8p21.1
Quick LinksEntrez ID:157574; OMIM: 608519; Uniprot ID:FBX16_HUMAN; ENSEMBL ID: ENSG00000214050; HGNC ID: 13618
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus1 / 5640121
neonate0 / 310970 
infant0 / 236200 
juvenile2 / 5555635
adult13 / 19391216
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor0 / 2638450 
glioma2 / 10688318
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor2 / 9635920
lung tumor0 / 1031270 
lymphoma2 / 7175527
non-neoplasia0 / 972500 
normal25 / 33603077
ovarian tumor1 / 7668213
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor1 / 1249498
soft tissue/muscle tissue tumor3 / 12519123
uterine tumor4 / 9025744
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow1 / 4880120
brain6 / 11009895
cervix0 / 481710 
connective tissue2 / 14925513
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye3 / 21105414
heart0 / 896260 
intestine0 / 2344720 
kidney3 / 21177714
larynx0 / 241450 
liver2 / 2077439
lung3 / 3369748
lymph0 / 442700 
lymph node1 / 9161010
mammary gland1 / 1532716
mouth0 / 670520 
muscle1 / 1077159
nerve0 / 157680 
ovary1 / 1020519
pancreas5 / 21481223
parathyroid1 / 2053948
pharynx2 / 4132848
pituitary gland1 / 1658560
placenta0 / 2808250 
prostate3 / 18934515
salivary gland0 / 201550 
skin2 / 2105749
spleen0 / 539520 
stomach0 / 966190 
testis1 / 3304423
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus5 / 23287821
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_1020_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.13 ± 0.82
Basal Forebrain3.96 ± 0.47
Basal Part of Pons4.55 ± 0.37
Cerebellar Cortex4.25 ± 0.31
Cerebellar Nuclei3.96 ± 0.56
Claustrum3.95 ± 0.96
Epithalamus3.8 ± 0.54
Frontal Lobe4.1 ± 0.55
Globus Pallidus2.76 ± 1
Hypothalamus4.05 ± 0.65
Insula4.25 ± 0.53
Limbic Lobe3.87 ± 0.67
Mesencephalon4.08 ± 0.75
Myelencephalon3.95 ± 0.67
Occipital Lobe3.76 ± 0.69
Parietal Lobe4.17 ± 0.64
Pontine Tegmentum3.99 ± 0.67
Striatum3.89 ± 0.61
Subthalamus3.95 ± 0.35
Temporal Lobe4.09 ± 0.54
Thalamus3.85 ± 0.56
White Matter2.19 ± 0.47
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Fbxo16CBCerebellum1.47
2.06
Fbxo16CTXCerebral cortex5.62
4.03
Fbxo16HIPHippocampal region2.6
2.62
Fbxo16HPFHippocampal formation3.19
2.82
Fbxo16HYHypothalamus0.49
0.31
Fbxo16LSXLateral septal complex0.16
0.1
Fbxo16MBMidbrain0.86
0.91
Fbxo16MYMedulla4.96
5.05
Fbxo16OLFOlfactory bulb6.78
5.47
Fbxo16PPons2.13
2.47
Fbxo16PALPallidum1.51
1.26
Fbxo16RHPRetrohippocampal region4.15
2.94
Fbxo16sAMYStriatum-like amygdalar nuclei10.49
6.93
Fbxo16STRStriatum2.39
1.62
Fbxo16STRdStriatum dorsal region1.71
1.19
Fbxo16STRvStriatum ventral region1.36
0.87
Fbxo16THThalamus0.79
0.72
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018