AutismKB 2.0

Annotation Detail for CYP11B1


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Basic Information Top
Gene Symbol:CYP11B1 ( CPN1,CYP11B,DKFZp686B05283,FHI,FLJ36771,P450C11 )
Gene Full Name: cytochrome P450, family 11, subfamily B, polypeptide 1
Band: 8q24.3
Quick LinksEntrez ID:1584; OMIM: 610613; Uniprot ID:C11B1_HUMAN; ENSEMBL ID: ENSG00000160882; HGNC ID: 2591
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus4 / 5640127
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult63 / 193912132
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor6 / 12794468
bladder carcinoma0 / 174750 
breast (mammary gland) tumor5 / 9417853
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor0 / 2638450 
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal109 / 336030732
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland103 / 331973102
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain1 / 11009890 
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye0 / 2110540 
heart0 / 896260 
intestine0 / 2344720 
kidney1 / 2117774
larynx0 / 241450 
liver0 / 2077430 
lung0 / 3369740 
lymph0 / 442700 
lymph node0 / 916100 
mammary gland5 / 15327132
mouth0 / 670520 
muscle4 / 10771537
nerve0 / 157680 
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta2 / 2808257
prostate0 / 1893450 
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach0 / 966190 
testis1 / 3304423
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 214610_at
Cell line Expression level Expression bar
721_B_lymphoblasts6.85
Adipocyte6.1
AdrenalCortex9768.8
Adrenalgland5515.4
Amygdala6.5
Appendix6.9
AtrioventricularNode5.05
BDCA4+_DentriticCells6.1
Bonemarrow6.55
BronchialEpithelialCells5.95
CD105+_Endothelial6.1
CD14+_Monocytes6.45
CD19+_BCells(neg._sel.)6.4
CD33+_Myeloid7.6
CD34+7.7
CD4+_Tcells6.75
CD56+_NKCells6.8
CD71+_EarlyErythroid5.85
CD8+_Tcells5.8
CardiacMyocytes7.75
Caudatenucleus5.55
Cerebellum4.95
CerebellumPeduncles7.15
CiliaryGanglion5
CingulateCortex6.45
Colorectaladenocarcinoma6.1
DorsalRootGanglion5.05
FetalThyroid5.95
Fetalbrain6.15
Fetalliver5.45
Fetallung4.85
GlobusPallidus4.65
Heart10.1
Hypothalamus6.75
Kidney5.4
Leukemia_chronicMyelogenousK-5625.5
Leukemia_promyelocytic-HL-605.4
Leukemialymphoblastic(MOLT-4)4.75
Liver8.4
Lung6.8
Lymphnode5.15
Lymphoma_burkitts(Daudi)7.75
Lymphoma_burkitts(Raji)8.7
MedullaOblongata5.65
OccipitalLobe5.5
OlfactoryBulb4.85
Ovary4.3
Pancreas4.9
PancreaticIslet6.5
ParietalLobe6.7
Pituitary7.05
Placenta6.05
Pons6.05
PrefrontalCortex7.75
Prostate7.05
Salivarygland4.8
SkeletalMuscle8.4
Skin4.95
SmoothMuscle6.9
Spinalcord6.55
SubthalamicNucleus5.55
SuperiorCervicalGanglion7.15
TemporalLobe5.7
Testis5.3
TestisGermCell5.1
TestisIntersitial5.25
TestisLeydigCell6.3
TestisSeminiferousTubule5.25
Thalamus6.35
Thymus4.6
Thyroid7.35
Tongue6.65
Tonsil6.1
Trachea5.1
TrigeminalGanglion7.6
Uterus4.9
UterusCorpus5.85
WholeBlood6.6
Wholebrain5.25
colon6.1
pineal_day7.5
pineal_night7.34
retina7.4
small_intestine5.85
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P329424
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.08 ± 1.08
Basal Forebrain1.52 ± 0.18
Basal Part of Pons1.2 ± 0.36
Cerebellar Cortex1.41 ± 0.69
Cerebellar Nuclei1.81 ± 0.74
Claustrum2.42 ± 0.88
Epithalamus1.27 ± 0.76
Frontal Lobe1.38 ± 0.59
Globus Pallidus2.04 ± 0.36
Hypothalamus1.69 ± 0.73
Insula1.53 ± 0.54
Limbic Lobe1.56 ± 0.63
Mesencephalon1.7 ± 0.72
Myelencephalon1.59 ± 0.66
Occipital Lobe1.62 ± 0.67
Parietal Lobe1.58 ± 0.76
Pontine Tegmentum1.64 ± 0.71
Striatum1.9 ± 0.72
Subthalamus1.69 ± 0.63
Temporal Lobe1.48 ± 0.69
Thalamus1.54 ± 0.6
White Matter2.12 ± 0.41
Mouse Brain ISH
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
C11B1_HUMAN_13 15 13 27 VPWLSLQRAQALGTR PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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