AutismKB 2.0

Annotation Detail for MOSPD2


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Basic Information Top
Gene Symbol:MOSPD2 ( DKFZp686C1553,MGC26706 )
Gene Full Name: motile sperm domain containing 2
Band: Xp22.2
Quick LinksEntrez ID:158747; OMIM: NA; Uniprot ID:MSPD2_HUMAN; ENSEMBL ID: ENSG00000130150; HGNC ID: 28381
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst3 / 6231948
fetus14 / 56401224
neonate1 / 3109732
infant0 / 236200 
juvenile2 / 5555635
adult41 / 193912121
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor0 / 941780 
cervical tumor1 / 3436629
chondrosarcoma3 / 8282336
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor4 / 11936933
germ cell tumor4 / 26384515
glioma1 / 1068839
head and neck tumor2 / 13630214
kidney tumor2 / 6895929
leukemia1 / 9584210
liver tumor0 / 963590 
lung tumor1 / 1031279
lymphoma0 / 717550 
non-neoplasia1 / 9725010
normal127 / 336030737
ovarian tumor3 / 7668239
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer1 / 1026809
retinoblastoma1 / 4635621
skin tumor3 / 12494924
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland1 / 3319730
ascites0 / 400150 
bladder3 / 29757100
blood7 / 12347856
bone2 / 7165527
bone marrow0 / 488010 
brain43 / 110098939
cervix1 / 4817120
connective tissue3 / 14925520
ear0 / 162120 
embryonic tissue7 / 21572232
esophagus0 / 202090 
eye3 / 21105414
heart0 / 896260 
intestine1 / 2344724
kidney8 / 21177737
larynx0 / 241450 
liver4 / 20774319
lung2 / 3369745
lymph0 / 442700 
lymph node9 / 9161098
mammary gland1 / 1532716
mouth1 / 6705214
muscle0 / 1077150 
nerve1 / 1576863
ovary3 / 10205129
pancreas5 / 21481223
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland1 / 1658560
placenta9 / 28082532
prostate7 / 18934536
salivary gland1 / 2015549
skin4 / 21057418
spleen3 / 5395255
stomach4 / 9661941
testis7 / 33044221
thymus1 / 8113112
thyroid1 / 4747321
tonsil0 / 169990 
trachea2 / 5241338
umbilical cord0 / 136800 
uterus5 / 23287821
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 221895_at
Cell line Expression level Expression bar
721_B_lymphoblasts17.05
Adipocyte16.65
AdrenalCortex5.45
Adrenalgland5.25
Amygdala12.15
Appendix9.3
AtrioventricularNode8.9
BDCA4+_DentriticCells17.65
Bonemarrow6.9
BronchialEpithelialCells6.25
CD105+_Endothelial7.7
CD14+_Monocytes54.6
CD19+_BCells(neg._sel.)12.25
CD33+_Myeloid149.85
CD34+16.1
CD4+_Tcells7
CD56+_NKCells23
CD71+_EarlyErythroid4.7
CD8+_Tcells8
CardiacMyocytes8.1
Caudatenucleus8.05
Cerebellum5.35
CerebellumPeduncles7
CiliaryGanglion6.55
CingulateCortex7.7
Colorectaladenocarcinoma7.1
DorsalRootGanglion5.05
FetalThyroid8.7
Fetalbrain5.35
Fetalliver5.65
Fetallung5.45
GlobusPallidus4.35
Heart7.45
Hypothalamus18.45
Kidney6.15
Leukemia_chronicMyelogenousK-5627.3
Leukemia_promyelocytic-HL-604.95
Leukemialymphoblastic(MOLT-4)4.75
Liver7.9
Lung6.65
Lymphnode5.45
Lymphoma_burkitts(Daudi)7.5
Lymphoma_burkitts(Raji)11.05
MedullaOblongata20.25
OccipitalLobe20.35
OlfactoryBulb17.1
Ovary4.35
Pancreas4.3
PancreaticIslet6.4
ParietalLobe17
Pituitary6.95
Placenta6.5
Pons10.6
PrefrontalCortex10.2
Prostate5.8
Salivarygland5
SkeletalMuscle9.05
Skin6.5
SmoothMuscle7.55
Spinalcord11.1
SubthalamicNucleus6.2
SuperiorCervicalGanglion10.6
TemporalLobe6.75
Testis5.4
TestisGermCell5.55
TestisIntersitial6.2
TestisLeydigCell6.25
TestisSeminiferousTubule5.45
Thalamus6.25
Thymus4.45
Thyroid7.9
Tongue5.8
Tonsil7.85
Trachea5.1
TrigeminalGanglion6
Uterus5.1
UterusCorpus7.05
WholeBlood33.2
Wholebrain6.55
colon6.35
pineal_day9.08
pineal_night9.12
retina22.625
small_intestine5.85
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P126093
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.88 ± 0.7
Basal Forebrain3.75 ± 0.7
Basal Part of Pons4 ± 0.61
Cerebellar Cortex3.83 ± 0.45
Cerebellar Nuclei4.77 ± 0.71
Claustrum3.98 ± 0.7
Epithalamus4.09 ± 0.64
Frontal Lobe3.93 ± 0.63
Globus Pallidus5.14 ± 0.4
Hypothalamus3.86 ± 0.65
Insula3.81 ± 0.61
Limbic Lobe3.75 ± 0.56
Mesencephalon3.96 ± 0.7
Myelencephalon4.01 ± 0.6
Occipital Lobe3.98 ± 0.5
Parietal Lobe3.84 ± 0.63
Pontine Tegmentum4.22 ± 0.48
Striatum4.19 ± 0.57
Subthalamus4.39 ± 0.77
Temporal Lobe3.85 ± 0.58
Thalamus4.14 ± 0.59
White Matter6.45 ± 0.35
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Mospd2CBCerebellum8.93
9.99
Mospd2CTXCerebral cortex16.14
11.43
Mospd2HIPHippocampal region13.02
13.78
Mospd2HPFHippocampal formation13.38
12.26
Mospd2HYHypothalamus5.95
4.8
Mospd2LSXLateral septal complex12.03
7.66
Mospd2MBMidbrain6.22
5.78
Mospd2MYMedulla6.55
6.87
Mospd2OLFOlfactory bulb16.74
11.85
Mospd2PPons7.02
7.55
Mospd2PALPallidum7.82
6.67
Mospd2RHPRetrohippocampal region14.61
10.44
Mospd2sAMYStriatum-like amygdalar nuclei5.22
3.45
Mospd2STRStriatum15.16
10.6
Mospd2STRdStriatum dorsal region16.25
11.79
Mospd2STRvStriatum ventral region18.77
11.88
Mospd2THThalamus13.85
11.68
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00429694 22 325 346 GPLLHISPAEELYFGSTESGEK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018