AutismKB 2.0

Annotation Detail for DAB1


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Basic Information Top
Gene Symbol:DAB1 ( - )
Gene Full Name: disabled homolog 1 (Drosophila)
Band: 1p32.2
Quick LinksEntrez ID:1600; OMIM: 603448; Uniprot ID:DAB1_HUMAN; ENSEMBL ID: ENSG00000173406; HGNC ID: 2661
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst4 / 6231964
fetus37 / 56401265
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult58 / 193912129
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor4 / 26384515
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor4 / 6895958
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal78 / 336030723
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor44 / 125191351
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain47 / 110098942
cervix0 / 481710 
connective tissue44 / 149255294
ear0 / 162120 
embryonic tissue5 / 21572223
esophagus0 / 202090 
eye2 / 2110549
heart0 / 896260 
intestine0 / 2344720 
kidney4 / 21177718
larynx0 / 241450 
liver3 / 20774314
lung1 / 3369742
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas1 / 2148124
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate3 / 18934515
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach0 / 966190 
testis1 / 3304423
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 220611_at
Cell line Expression level Expression bar
721_B_lymphoblasts4.7
Adipocyte3.75
AdrenalCortex4
Adrenalgland3.25
Amygdala4
Appendix3.85
AtrioventricularNode5.6
BDCA4+_DentriticCells4.1
Bonemarrow3.8
BronchialEpithelialCells3.65
CD105+_Endothelial3.8
CD14+_Monocytes4.05
CD19+_BCells(neg._sel.)4
CD33+_Myeloid4.8
CD34+4.85
CD4+_Tcells4.1
CD56+_NKCells4.45
CD71+_EarlyErythroid3.6
CD8+_Tcells3.7
CardiacMyocytes4.85
Caudatenucleus3.45
Cerebellum3.2
CerebellumPeduncles4.3
CiliaryGanglion3.1
CingulateCortex4
Colorectaladenocarcinoma3.8
DorsalRootGanglion3.75
FetalThyroid3.7
Fetalbrain4.3
Fetalliver3.4
Fetallung3.05
GlobusPallidus3
Heart4.85
Hypothalamus4.1
Kidney3.3
Leukemia_chronicMyelogenousK-5626.05
Leukemia_promyelocytic-HL-603.4
Leukemialymphoblastic(MOLT-4)3.1
Liver5.2
Lung4.15
Lymphnode3.25
Lymphoma_burkitts(Daudi)4.9
Lymphoma_burkitts(Raji)5.35
MedullaOblongata3.7
OccipitalLobe3.45
OlfactoryBulb3.05
Ovary2.5
Pancreas3.05
PancreaticIslet4.05
ParietalLobe4.05
Pituitary4.45
Placenta3.95
Pons4.05
PrefrontalCortex4.75
Prostate4.45
Salivarygland3.05
SkeletalMuscle4.75
Skin3.1
SmoothMuscle4.25
Spinalcord4.1
SubthalamicNucleus3.5
SuperiorCervicalGanglion5.1
TemporalLobe3.5
Testis3.25
TestisGermCell3.1
TestisIntersitial3.15
TestisLeydigCell3.85
TestisSeminiferousTubule3.3
Thalamus3.9
Thymus2.95
Thyroid4.7
Tongue4.1
Tonsil3.65
Trachea3.15
TrigeminalGanglion5.85
Uterus3.15
UterusCorpus5.25
WholeBlood4.15
Wholebrain3.2
colon3.9
pineal_day4.82
pineal_night4.68
retina4.8
small_intestine3.7
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_10963_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.96 ± 0.91
Basal Forebrain2.28 ± 0.26
Basal Part of Pons2.31 ± 0.62
Cerebellar Cortex3.24 ± 0.54
Cerebellar Nuclei2.72 ± 0.75
Claustrum3.11 ± 0.87
Epithalamus2.04 ± 0.85
Frontal Lobe2.47 ± 0.78
Globus Pallidus2.32 ± 0.62
Hypothalamus2.45 ± 0.68
Insula2.31 ± 0.57
Limbic Lobe2.77 ± 0.63
Mesencephalon2.62 ± 0.81
Myelencephalon2.55 ± 0.73
Occipital Lobe2.38 ± 0.75
Parietal Lobe2.49 ± 0.85
Pontine Tegmentum2.56 ± 0.72
Striatum1.9 ± 0.58
Subthalamus2.67 ± 0.73
Temporal Lobe2.55 ± 0.75
Thalamus2.34 ± 0.76
White Matter2.34 ± 0.36
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Dab1CBCerebellum54.05
100
Dab1CTXCerebral cortex100
100
Dab1HIPHippocampal region100
100
Dab1HPFHippocampal formation100
100
Dab1HYHypothalamus41.79
36.39
Dab1LSXLateral septal complex32.87
29.19
Dab1MBMidbrain54.45
55.25
Dab1MYMedulla28.74
35.69
Dab1OLFOlfactory bulb100
100
Dab1PPons37.68
42.59
Dab1PALPallidum46.28
46.45
Dab1RHPRetrohippocampal region100
100
Dab1sAMYStriatum-like amygdalar nuclei61.91
60.77
Dab1STRStriatum86
74.12
Dab1STRdStriatum dorsal region90.34
70.04
Dab1STRvStriatum ventral region100
100
Dab1THThalamus17.98
16.77
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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