AutismKB 2.0

Annotation Detail for DACH1


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Basic Information Top
Gene Symbol:DACH1 ( DACH,FLJ10138 )
Gene Full Name: dachshund homolog 1 (Drosophila)
Band: 13q21.33
Quick LinksEntrez ID:1602; OMIM: 603803; Uniprot ID:DACH1_HUMAN; ENSEMBL ID: ENSG00000165659; HGNC ID: 2663
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body3 / 7076142
blastocyst0 / 623190 
fetus23 / 56401240
neonate0 / 310970 
infant2 / 2362084
juvenile0 / 555560 
adult28 / 193912114
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor2 / 11424617
esophageal tumor0 / 172900 
gastrointestinal tumor3 / 11936925
germ cell tumor0 / 2638450 
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor2 / 6895929
leukemia1 / 9584210
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia3 / 9725030
normal74 / 336030722
ovarian tumor0 / 766820 
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS2 / 12568015
prostate cancer0 / 1026800 
retinoblastoma4 / 4635686
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor10 / 12519179
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites0 / 400150 
bladder0 / 297570 
blood1 / 1234788
bone0 / 716550 
bone marrow0 / 488010 
brain10 / 11009899
cervix0 / 481710 
connective tissue5 / 14925533
ear0 / 162120 
embryonic tissue6 / 21572227
esophagus0 / 202090 
eye14 / 21105466
heart1 / 8962611
intestine5 / 23447221
kidney8 / 21177737
larynx1 / 2414541
liver0 / 2077430 
lung9 / 33697426
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle2 / 10771518
nerve0 / 157680 
ovary0 / 1020510 
pancreas6 / 21481227
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta4 / 28082514
prostate2 / 18934510
salivary gland0 / 201550 
skin0 / 2105740 
spleen3 / 5395255
stomach0 / 966190 
testis12 / 33044236
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus7 / 23287830
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 205472_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts7.3
Adipocyte6.45
AdrenalCortex8.1
Adrenalgland6.05
Amygdala6.6
Appendix7.55
AtrioventricularNode6.25
BDCA4+_DentriticCells9.7
Bonemarrow7
BronchialEpithelialCells6.3
CD105+_Endothelial6.55
CD14+_Monocytes7
CD19+_BCells(neg._sel.)6.85
CD33+_Myeloid8.05
CD34+8.85
CD4+_Tcells6.85
CD56+_NKCells7.4
CD71+_EarlyErythroid6.35
CD8+_Tcells5.9
CardiacMyocytes10.45
Caudatenucleus6
Cerebellum5.45
CerebellumPeduncles7.95
CiliaryGanglion5.45
CingulateCortex7
Colorectaladenocarcinoma6.6
DorsalRootGanglion5.55
FetalThyroid6.55
Fetalbrain6.3
Fetalliver5.8
Fetallung5
GlobusPallidus5.2
Heart9.55
Hypothalamus6.85
Kidney5.9
Leukemia_chronicMyelogenousK-5625.95
Leukemia_promyelocytic-HL-605.9
Leukemialymphoblastic(MOLT-4)5.15
Liver9.6
Lung7.3
Lymphnode5.4
Lymphoma_burkitts(Daudi)8.8
Lymphoma_burkitts(Raji)10
MedullaOblongata6.1
OccipitalLobe5.9
OlfactoryBulb5.2
Ovary4.8
Pancreas5.5
PancreaticIslet7.15
ParietalLobe7.4
Pituitary7.65
Placenta6.5
Pons6.55
PrefrontalCortex8.15
Prostate8.55
Salivarygland5.55
SkeletalMuscle9.55
Skin5.85
SmoothMuscle7.4
Spinalcord7.1
SubthalamicNucleus6.3
SuperiorCervicalGanglion9.15
TemporalLobe6.25
Testis5.7
TestisGermCell5.55
TestisIntersitial5.65
TestisLeydigCell6.9
TestisSeminiferousTubule5.65
Thalamus6.95
Thymus5.05
Thyroid7.95
Tongue7.25
Tonsil6.55
Trachea5.45
TrigeminalGanglion13.05
Uterus5.2
UterusCorpus6.65
WholeBlood7.15
Wholebrain5.45
colon6.65
pineal_day39.42
pineal_night62.36
retina8
small_intestine6.35
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_9782_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.09 ± 0.71
Basal Forebrain8.17 ± 0.45
Basal Part of Pons8.33 ± 0.28
Cerebellar Cortex7.07 ± 0.22
Cerebellar Nuclei8.69 ± 0.34
Claustrum7.82 ± 0.65
Epithalamus7.33 ± 1.18
Frontal Lobe7.98 ± 0.51
Globus Pallidus7.01 ± 0.4
Hypothalamus9 ± 0.6
Insula7.73 ± 0.43
Limbic Lobe6.99 ± 0.72
Mesencephalon7.73 ± 0.97
Myelencephalon7.67 ± 0.94
Occipital Lobe7.05 ± 0.71
Parietal Lobe7.48 ± 0.63
Pontine Tegmentum7.65 ± 0.67
Striatum9.84 ± 0.7
Subthalamus7.35 ± 0.26
Temporal Lobe7.33 ± 0.54
Thalamus7.26 ± 0.46
White Matter5.36 ± 0.41
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Dach1CBCerebellum31.52
80.23
Dach1CTXCerebral cortex22.43
17.31
Dach1HIPHippocampal region17.53
21.59
Dach1HPFHippocampal formation20.38
21.45
Dach1HYHypothalamus20.46
17.38
Dach1LSXLateral septal complex17.61
14.6
Dach1MBMidbrain20.13
20.61
Dach1MYMedulla36.19
41.81
Dach1OLFOlfactory bulb44.14
43.93
Dach1PPons29.27
30.56
Dach1PALPallidum23.41
22.7
Dach1RHPRetrohippocampal region25.49
21.98
Dach1sAMYStriatum-like amygdalar nuclei27.64
24.71
Dach1STRStriatum98.68
97.81
Dach1STRdStriatum dorsal region100
100
Dach1STRvStriatum ventral region66.42
51.37
Dach1THThalamus13.31
13.15
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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