AutismKB 2.0

Annotation Detail for DAG1


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Basic Information Top
Gene Symbol:DAG1 ( 156DAG,A3a,AGRNR,DAG )
Gene Full Name: dystroglycan 1 (dystrophin-associated glycoprotein 1)
Band: 3p21.31
Quick LinksEntrez ID:1605; OMIM: 128239; Uniprot ID:DAG1_HUMAN; ENSEMBL ID: ENSG00000173402; HGNC ID: 2666
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body17 / 70761240
blastocyst7 / 62319112
fetus59 / 564012104
neonate2 / 3109764
infant4 / 23620169
juvenile6 / 55556107
adult228 / 1939121117
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor4 / 12794312
bladder carcinoma1 / 1747557
breast (mammary gland) tumor6 / 9417863
cervical tumor0 / 343660 
chondrosarcoma9 / 82823108
colorectal tumor15 / 114246131
esophageal tumor3 / 17290173
gastrointestinal tumor14 / 119369117
germ cell tumor49 / 263845185
glioma30 / 106883280
head and neck tumor8 / 13630258
kidney tumor8 / 68959116
leukemia2 / 9584220
liver tumor4 / 9635941
lung tumor7 / 10312767
lymphoma0 / 717550 
non-neoplasia9 / 9725092
normal351 / 3360307104
ovarian tumor12 / 76682156
pancreatic tumor16 / 104616152
primitive neuroectodermal tumor of the CNS5 / 12568039
prostate cancer10 / 10268097
retinoblastoma2 / 4635643
skin tumor12 / 12494996
soft tissue/muscle tissue tumor8 / 12519163
uterine tumor6 / 9025766
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue2 / 13106152
adrenal gland4 / 33197120
ascites3 / 4001574
bladder4 / 29757134
blood3 / 12347824
bone6 / 7165583
bone marrow1 / 4880120
brain116 / 1100989105
cervix9 / 48171186
connective tissue9 / 14925560
ear1 / 1621261
embryonic tissue36 / 215722166
esophagus3 / 20209148
eye16 / 21105475
heart12 / 89626133
intestine29 / 234472123
kidney31 / 211777146
larynx4 / 24145165
liver8 / 20774338
lung39 / 336974115
lymph0 / 442700 
lymph node0 / 916100 
mammary gland13 / 15327184
mouth4 / 6705259
muscle22 / 107715204
nerve2 / 15768126
ovary14 / 102051137
pancreas24 / 214812111
parathyroid3 / 20539146
pharynx3 / 4132872
pituitary gland1 / 1658560
placenta49 / 280825174
prostate26 / 189345137
salivary gland0 / 201550 
skin34 / 210574161
spleen1 / 5395218
stomach10 / 96619103
testis41 / 330442124
thymus0 / 811310 
thyroid2 / 4747342
tonsil0 / 169990 
trachea8 / 52413152
umbilical cord2 / 13680146
uterus19 / 23287881
vascular4 / 5178077
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 205417_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts109.3
Adipocyte342.4
AdrenalCortex173.1
Adrenalgland256.9
Amygdala274.9
Appendix166.1
AtrioventricularNode138.7
BDCA4+_DentriticCells68.85
Bonemarrow88.2
BronchialEpithelialCells392.55
CD105+_Endothelial102.85
CD14+_Monocytes68.7
CD19+_BCells(neg._sel.)59.55
CD33+_Myeloid76.75
CD34+189.2
CD4+_Tcells52
CD56+_NKCells130.1
CD71+_EarlyErythroid94.65
CD8+_Tcells50.05
CardiacMyocytes495.95
Caudatenucleus207.2
Cerebellum258.65
CerebellumPeduncles337.65
CiliaryGanglion242.2
CingulateCortex154.15
Colorectaladenocarcinoma584.55
DorsalRootGanglion541.55
FetalThyroid466.85
Fetalbrain278.25
Fetalliver84.2
Fetallung250.75
GlobusPallidus105.05
Heart852.6
Hypothalamus317.35
Kidney257.25
Leukemia_chronicMyelogenousK-56255.65
Leukemia_promyelocytic-HL-6052.45
Leukemialymphoblastic(MOLT-4)45.35
Liver617.6
Lung963.1
Lymphnode75.55
Lymphoma_burkitts(Daudi)57.25
Lymphoma_burkitts(Raji)121.05
MedullaOblongata194.65
OccipitalLobe229.35
OlfactoryBulb1490.8
Ovary81
Pancreas226.15
PancreaticIslet281.5
ParietalLobe212.95
Pituitary234.15
Placenta3209.8
Pons201.35
PrefrontalCortex510.3
Prostate628.65
Salivarygland140.2
SkeletalMuscle357.45
Skin168.35
SmoothMuscle323.6
Spinalcord329.9
SubthalamicNucleus120.15
SuperiorCervicalGanglion96.55
TemporalLobe91.2
Testis602.45
TestisGermCell690
TestisIntersitial251.65
TestisLeydigCell186.15
TestisSeminiferousTubule367
Thalamus194
Thymus122.55
Thyroid440.75
Tongue292.3
Tonsil130.15
Trachea164.9
TrigeminalGanglion155.5
Uterus326
UterusCorpus160.95
WholeBlood46.3
Wholebrain412.05
colon291.5
pineal_day264.86
pineal_night262.72
retina412.325
small_intestine269.2
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P212579
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.24 ± 0.76
Basal Forebrain4.08 ± 0.36
Basal Part of Pons3.63 ± 0.55
Cerebellar Cortex3.82 ± 0.45
Cerebellar Nuclei4.03 ± 0.51
Claustrum3.96 ± 0.7
Epithalamus4.4 ± 0.53
Frontal Lobe3.84 ± 0.55
Globus Pallidus5.03 ± 0.52
Hypothalamus3.47 ± 0.69
Insula4.17 ± 0.79
Limbic Lobe4.01 ± 0.58
Mesencephalon4.04 ± 0.58
Myelencephalon4.07 ± 0.58
Occipital Lobe4.23 ± 0.54
Parietal Lobe4.04 ± 0.62
Pontine Tegmentum3.97 ± 0.66
Striatum4.36 ± 0.52
Subthalamus3.92 ± 0.88
Temporal Lobe3.9 ± 0.59
Thalamus4.12 ± 0.49
White Matter4.46 ± 0.47
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Dag1CBCerebellum45.26
74.89
Dag1CTXCerebral cortex84.41
77.13
Dag1HIPHippocampal region70.04
75.52
Dag1HPFHippocampal formation71.79
73.01
Dag1HYHypothalamus47.95
47.27
Dag1LSXLateral septal complex56.19
54.54
Dag1MBMidbrain43.19
46.57
Dag1MYMedulla50.08
55.02
Dag1OLFOlfactory bulb72.61
69.13
Dag1PPons44.84
53.3
Dag1PALPallidum42
45
Dag1RHPRetrohippocampal region75.37
70.27
Dag1sAMYStriatum-like amygdalar nuclei59.09
55.72
Dag1STRStriatum70.89
65.34
Dag1STRdStriatum dorsal region74.7
68.22
Dag1STRvStriatum ventral region69.25
63.71
Dag1THThalamus54.2
53.78
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00009343 13 702 714 ATSITVTGSGSCR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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