AutismKB 2.0

Annotation Detail for DGKG


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Basic Information Top
Gene Symbol:DGKG ( DAGK3,DGK-GAMMA,MGC104993,MGC133330 )
Gene Full Name: diacylglycerol kinase, gamma 90kDa
Band: 3q27.2-q27.3
Quick LinksEntrez ID:1608; OMIM: 601854; Uniprot ID:DGKG_HUMAN; ENSEMBL ID: ENSG00000058866; HGNC ID: 2853
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus1 / 5640121
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult43 / 193912122
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor2 / 2638457
glioma5 / 10688346
head and neck tumor1 / 1363027
kidney tumor1 / 6895914
leukemia10 / 95842104
liver tumor0 / 963590 
lung tumor1 / 1031279
lymphoma0 / 717550 
non-neoplasia1 / 9725010
normal65 / 336030719
ovarian tumor3 / 7668239
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor1 / 1249498
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland5 / 33197150
ascites0 / 400150 
bladder0 / 297570 
blood10 / 12347880
bone0 / 716550 
bone marrow0 / 488010 
brain44 / 110098939
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye4 / 21105418
heart4 / 8962644
intestine0 / 2344720 
kidney1 / 2117774
larynx1 / 2414541
liver0 / 2077430 
lung9 / 33697426
lymph0 / 442700 
lymph node2 / 9161021
mammary gland0 / 1532710 
mouth0 / 670520 
muscle2 / 10771518
nerve0 / 157680 
ovary3 / 10205129
pancreas1 / 2148124
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland1 / 1658560
placenta2 / 2808257
prostate0 / 1893450 
salivary gland0 / 201550 
skin2 / 2105749
spleen0 / 539520 
stomach1 / 9661910
testis0 / 3304420 
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 206395_at
Cell line Expression level Expression bar
721_B_lymphoblasts6.1
Adipocyte4.85
AdrenalCortex5.25
Adrenalgland4.15
Amygdala5.2
Appendix8.35
AtrioventricularNode3.8
BDCA4+_DentriticCells5.15
Bonemarrow5.9
BronchialEpithelialCells4.8
CD105+_Endothelial4.95
CD14+_Monocytes5.2
CD19+_BCells(neg._sel.)5.2
CD33+_Myeloid7.3
CD34+6.2
CD4+_Tcells5.2
CD56+_NKCells5.85
CD71+_EarlyErythroid4.5
CD8+_Tcells4.7
CardiacMyocytes6.85
Caudatenucleus4.35
Cerebellum21.5
CerebellumPeduncles9.4
CiliaryGanglion3.55
CingulateCortex5.05
Colorectaladenocarcinoma4.9
DorsalRootGanglion3.85
FetalThyroid4.8
Fetalbrain4.9
Fetalliver4.2
Fetallung4
GlobusPallidus3.6
Heart6.35
Hypothalamus5.2
Kidney3.95
Leukemia_chronicMyelogenousK-5624.35
Leukemia_promyelocytic-HL-604.3
Leukemialymphoblastic(MOLT-4)3.95
Liver6.7
Lung5.6
Lymphnode4.2
Lymphoma_burkitts(Daudi)6.25
Lymphoma_burkitts(Raji)10.9
MedullaOblongata4.55
OccipitalLobe4.4
OlfactoryBulb3.85
Ovary3.85
Pancreas3.9
PancreaticIslet5.2
ParietalLobe5.2
Pituitary5.9
Placenta5.05
Pons4.7
PrefrontalCortex6.25
Prostate5.7
Salivarygland4.55
SkeletalMuscle5.9
Skin3.8
SmoothMuscle5.55
Spinalcord5.15
SubthalamicNucleus4.55
SuperiorCervicalGanglion6.15
TemporalLobe4.65
Testis4.2
TestisGermCell4.1
TestisIntersitial4.1
TestisLeydigCell5.45
TestisSeminiferousTubule4.2
Thalamus4.9
Thymus3.85
Thyroid6.1
Tongue4.85
Tonsil4.75
Trachea4.1
TrigeminalGanglion5.15
Uterus4.05
UterusCorpus5.4
WholeBlood5.3
Wholebrain4.3
colon4.95
pineal_day6
pineal_night5.92
retina5.95
small_intestine4.7
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P40926
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.25 ± 0.49
Basal Forebrain6.87 ± 0.93
Basal Part of Pons8.14 ± 0.23
Cerebellar Cortex7.82 ± 0.4
Cerebellar Nuclei6.56 ± 0.55
Claustrum6.13 ± 0.55
Epithalamus5.93 ± 0.53
Frontal Lobe6.96 ± 0.64
Globus Pallidus6.66 ± 0.57
Hypothalamus6.66 ± 0.51
Insula7.26 ± 0.58
Limbic Lobe7.62 ± 0.54
Mesencephalon6.67 ± 0.74
Myelencephalon6.93 ± 0.81
Occipital Lobe7.41 ± 0.53
Parietal Lobe6.91 ± 0.58
Pontine Tegmentum6.82 ± 0.49
Striatum5.79 ± 0.71
Subthalamus6.14 ± 0.53
Temporal Lobe7.02 ± 0.46
Thalamus6.72 ± 0.63
White Matter4.96 ± 0.48
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
DgkgCBCerebellum23.07
66.91
DgkgCTXCerebral cortex21.6
22.99
DgkgHIPHippocampal region73.82
70.78
DgkgHPFHippocampal formation65.16
62.23
DgkgHYHypothalamus21.78
21.79
DgkgLSXLateral septal complex74.54
69.72
DgkgMBMidbrain2.77
4.07
DgkgMYMedulla2.05
4.28
DgkgOLFOlfactory bulb29.27
41.27
DgkgPPons6.96
12.5
DgkgPALPallidum22.51
23.47
DgkgRHPRetrohippocampal region37.58
50.13
DgkgsAMYStriatum-like amygdalar nuclei43.1
46.36
DgkgSTRStriatum36.81
37.36
DgkgSTRdStriatum dorsal region30.99
25.63
DgkgSTRvStriatum ventral region30.46
27.46
DgkgTHThalamus13.11
16.19
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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