AutismKB 2.0

Annotation Detail for DGKH


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Basic Information Top
Gene Symbol:DGKH ( DGKeta,DKFZp761I1510 )
Gene Full Name: diacylglycerol kinase, eta
Band: 13q14.11
Quick LinksEntrez ID:160851; OMIM: 604071; Uniprot ID:DGKH_HUMAN; ENSEMBL ID: ENSG00000102780; HGNC ID: 2854
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus8 / 56401214
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult51 / 193912126
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor8 / 11424670
esophageal tumor1 / 1729057
gastrointestinal tumor2 / 11936916
germ cell tumor3 / 26384511
glioma0 / 1068830 
head and neck tumor4 / 13630229
kidney tumor2 / 6895929
leukemia2 / 9584220
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma1 / 7175513
non-neoplasia3 / 9725030
normal63 / 336030718
ovarian tumor3 / 7668239
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer3 / 10268029
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland2 / 3319760
ascites0 / 400150 
bladder2 / 2975767
blood1 / 1234788
bone1 / 7165513
bone marrow0 / 488010 
brain18 / 110098916
cervix0 / 481710 
connective tissue2 / 14925513
ear1 / 1621261
embryonic tissue0 / 2157220 
esophagus1 / 2020949
eye4 / 21105418
heart1 / 8962611
intestine10 / 23447242
kidney3 / 21177714
larynx0 / 241450 
liver2 / 2077439
lung8 / 33697423
lymph1 / 4427022
lymph node2 / 9161021
mammary gland1 / 1532716
mouth2 / 6705229
muscle0 / 1077150 
nerve0 / 157680 
ovary3 / 10205129
pancreas5 / 21481223
parathyroid0 / 205390 
pharynx2 / 4132848
pituitary gland0 / 165850 
placenta8 / 28082528
prostate4 / 18934521
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach3 / 9661931
testis13 / 33044239
thymus3 / 8113136
thyroid0 / 474730 
tonsil0 / 169990 
trachea2 / 5241338
umbilical cord0 / 136800 
uterus6 / 23287825
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_14241_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.78 ± 0.76
Basal Forebrain6.9 ± 0.67
Basal Part of Pons6.63 ± 0.61
Cerebellar Cortex6.96 ± 0.28
Cerebellar Nuclei5.31 ± 0.66
Claustrum7.47 ± 0.66
Epithalamus5.42 ± 0.87
Frontal Lobe6.49 ± 0.67
Globus Pallidus5.32 ± 0.72
Hypothalamus6.18 ± 0.54
Insula6.78 ± 0.41
Limbic Lobe7.13 ± 0.66
Mesencephalon6.47 ± 0.84
Myelencephalon6.67 ± 0.75
Occipital Lobe6.81 ± 0.6
Parietal Lobe6.51 ± 0.63
Pontine Tegmentum6.45 ± 0.71
Striatum8.37 ± 0.91
Subthalamus5 ± 0.54
Temporal Lobe6.58 ± 0.4
Thalamus7.1 ± 0.63
White Matter4.78 ± 0.2
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
DgkhCBCerebellum24.72
87.91
DgkhCTXCerebral cortex100
95.47
DgkhHIPHippocampal region88.38
100
DgkhHPFHippocampal formation87.21
100
DgkhHYHypothalamus10.94
8.56
DgkhLSXLateral septal complex100
99.38
DgkhMBMidbrain27.25
25.49
DgkhMYMedulla18.24
20.02
DgkhOLFOlfactory bulb83.57
82.47
DgkhPPons13.01
12.78
DgkhPALPallidum24.13
22.84
DgkhRHPRetrohippocampal region85.78
83.15
DgkhsAMYStriatum-like amygdalar nuclei37.42
29.73
DgkhSTRStriatum100
93.61
DgkhSTRdStriatum dorsal region100
99.25
DgkhSTRvStriatum ventral region100
95.55
DgkhTHThalamus59.09
55.81
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
DGKH_HUMAN_1069 12 1069 1080 VPLQLESPHEER PRIDE
PAp00433288 17 194 210 ESLSGVTSHGLSCEVCK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018