AutismKB 2.0

Annotation Detail for DAPK3


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Basic Information Top
Gene Symbol:DAPK3 ( FLJ36473,ZIP,ZIPK )
Gene Full Name: death-associated protein kinase 3
Band: 19p13.3
Quick LinksEntrez ID:1613; OMIM: 603289; Uniprot ID:DAPK3_HUMAN; ENSEMBL ID: ENSG00000167657; HGNC ID: 2676
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body6 / 7076184
blastocyst4 / 6231964
fetus17 / 56401230
neonate2 / 3109764
infant0 / 236200 
juvenile0 / 555560 
adult82 / 193912142
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor2 / 9417821
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor4 / 11424635
esophageal tumor2 / 17290115
gastrointestinal tumor4 / 11936933
germ cell tumor32 / 263845121
glioma9 / 10688384
head and neck tumor6 / 13630244
kidney tumor6 / 6895987
leukemia3 / 9584231
liver tumor3 / 9635931
lung tumor5 / 10312748
lymphoma0 / 717550 
non-neoplasia5 / 9725051
normal154 / 336030745
ovarian tumor0 / 766820 
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS8 / 12568063
prostate cancer1 / 1026809
retinoblastoma0 / 463560 
skin tumor4 / 12494932
soft tissue/muscle tissue tumor3 / 12519123
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder1 / 2975733
blood2 / 12347816
bone2 / 7165527
bone marrow0 / 488010 
brain41 / 110098937
cervix1 / 4817120
connective tissue3 / 14925520
ear0 / 162120 
embryonic tissue11 / 21572250
esophagus2 / 2020998
eye17 / 21105480
heart5 / 8962655
intestine13 / 23447255
kidney10 / 21177747
larynx0 / 241450 
liver4 / 20774319
lung15 / 33697444
lymph0 / 442700 
lymph node7 / 9161076
mammary gland9 / 15327158
mouth6 / 6705289
muscle1 / 1077159
nerve0 / 157680 
ovary2 / 10205119
pancreas6 / 21481227
parathyroid0 / 205390 
pharynx2 / 4132848
pituitary gland0 / 165850 
placenta15 / 28082553
prostate8 / 18934542
salivary gland1 / 2015549
skin14 / 21057466
spleen3 / 5395255
stomach5 / 9661951
testis12 / 33044236
thymus7 / 8113186
thyroid0 / 474730 
tonsil1 / 1699958
trachea0 / 524130 
umbilical cord1 / 1368073
uterus6 / 23287825
vascular7 / 51780135
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 203891_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts49.5
Adipocyte33.9
AdrenalCortex60.7
Adrenalgland18.5
Amygdala26.85
Appendix28.5
AtrioventricularNode28.9
BDCA4+_DentriticCells48.5
Bonemarrow27.25
BronchialEpithelialCells34.3
CD105+_Endothelial33.85
CD14+_Monocytes36.25
CD19+_BCells(neg._sel.)42.25
CD33+_Myeloid42.5
CD34+55.65
CD4+_Tcells60.3
CD56+_NKCells47.3
CD71+_EarlyErythroid40.65
CD8+_Tcells37.25
CardiacMyocytes63.45
Caudatenucleus20.8
Cerebellum23.3
CerebellumPeduncles37.4
CiliaryGanglion19.95
CingulateCortex31.95
Colorectaladenocarcinoma26.8
DorsalRootGanglion20.2
FetalThyroid29.5
Fetalbrain29.1
Fetalliver21.85
Fetallung16.1
GlobusPallidus44.9
Heart81.05
Hypothalamus20.35
Kidney21.35
Leukemia_chronicMyelogenousK-56224.2
Leukemia_promyelocytic-HL-6025.15
Leukemialymphoblastic(MOLT-4)18.85
Liver33.8
Lung47.3
Lymphnode20.45
Lymphoma_burkitts(Daudi)34.5
Lymphoma_burkitts(Raji)50.9
MedullaOblongata21.05
OccipitalLobe19.2
OlfactoryBulb21.8
Ovary16.8
Pancreas19.9
PancreaticIslet26.6
ParietalLobe28.7
Pituitary28.75
Placenta36.3
Pons46.35
PrefrontalCortex44.5
Prostate37.15
Salivarygland24.65
SkeletalMuscle50.55
Skin22.8
SmoothMuscle46.15
Spinalcord36.8
SubthalamicNucleus35.25
SuperiorCervicalGanglion18.15
TemporalLobe35.45
Testis29.8
TestisGermCell19.4
TestisIntersitial26.15
TestisLeydigCell33.3
TestisSeminiferousTubule27.35
Thalamus51.85
Thymus17.4
Thyroid34.7
Tongue33.65
Tonsil30.35
Trachea22.75
TrigeminalGanglion42.05
Uterus56
UterusCorpus34.5
WholeBlood20.45
Wholebrain26.5
colon31.25
pineal_day68.46
pineal_night91.54
retina46.475
small_intestine22.65
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_12147_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.72 ± 0.79
Basal Forebrain3.41 ± 0.68
Basal Part of Pons3.77 ± 0.78
Cerebellar Cortex3.72 ± 0.77
Cerebellar Nuclei3.32 ± 0.45
Claustrum3.4 ± 0.79
Epithalamus3.03 ± 0.89
Frontal Lobe3.69 ± 0.67
Globus Pallidus3.04 ± 0.53
Hypothalamus3.12 ± 0.47
Insula3.64 ± 0.58
Limbic Lobe3.4 ± 0.73
Mesencephalon3.47 ± 0.7
Myelencephalon3.38 ± 0.7
Occipital Lobe3.15 ± 0.71
Parietal Lobe3.5 ± 0.72
Pontine Tegmentum3.36 ± 0.7
Striatum2.78 ± 0.63
Subthalamus3.63 ± 0.57
Temporal Lobe3.55 ± 0.75
Thalamus3.22 ± 0.77
White Matter2.58 ± 0.43
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Dapk3CBCerebellum4.62
4.52
Dapk3CTXCerebral cortex9.8
6.95
Dapk3HIPHippocampal region11.66
11.34
Dapk3HPFHippocampal formation10.18
8.96
Dapk3HYHypothalamus0.82
0.64
Dapk3LSXLateral septal complex0.8
0.55
Dapk3MBMidbrain2.24
2.39
Dapk3MYMedulla4.97
6.26
Dapk3OLFOlfactory bulb4.96
4.3
Dapk3PPons4.19
5.05
Dapk3PALPallidum1.54
1.3
Dapk3RHPRetrohippocampal region7.9
5.83
Dapk3sAMYStriatum-like amygdalar nuclei1.26
0.87
Dapk3STRStriatum1.61
1.12
Dapk3STRdStriatum dorsal region1.62
1.17
Dapk3STRvStriatum ventral region2.41
1.49
Dapk3THThalamus1.86
1.59
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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