AutismKB 2.0

Annotation Detail for EML5


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Basic Information Top
Gene Symbol:EML5 ( DKFZp781D1122,EMAP-2 )
Gene Full Name: echinoderm microtubule associated protein like 5
Band: 14q31.3
Quick LinksEntrez ID:161436; OMIM: NA; Uniprot ID:EMAL5_HUMAN; ENSEMBL ID: ENSG00000165521; HGNC ID: 18197
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst0 / 623190 
fetus8 / 56401214
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult24 / 193912112
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor2 / 12794156
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor2 / 2638457
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia2 / 9584220
liver tumor2 / 9635920
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal50 / 336030714
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS4 / 12568031
prostate cancer4 / 10268038
retinoblastoma3 / 4635664
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland2 / 3319760
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow2 / 4880140
brain11 / 11009899
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue1 / 2157224
esophagus0 / 202090 
eye10 / 21105447
heart1 / 8962611
intestine0 / 2344720 
kidney2 / 2117779
larynx0 / 241450 
liver4 / 20774319
lung4 / 33697411
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle2 / 10771518
nerve2 / 15768126
ovary0 / 1020510 
pancreas4 / 21481218
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland2 / 16585120
placenta4 / 28082514
prostate6 / 18934531
salivary gland0 / 201550 
skin1 / 2105744
spleen1 / 5395218
stomach0 / 966190 
testis1 / 3304423
thymus1 / 8113112
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_72_PI416573500
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.19 ± 0.48
Basal Forebrain6.14 ± 0.23
Basal Part of Pons5.69 ± 0.42
Cerebellar Cortex6.72 ± 0.38
Cerebellar Nuclei5.73 ± 0.39
Claustrum5.53 ± 0.63
Epithalamus6.29 ± 0.56
Frontal Lobe5.71 ± 0.51
Globus Pallidus5.25 ± 0.4
Hypothalamus6.42 ± 0.24
Insula5.93 ± 0.41
Limbic Lobe6.23 ± 0.76
Mesencephalon6.06 ± 0.65
Myelencephalon5.89 ± 0.61
Occipital Lobe6.49 ± 0.6
Parietal Lobe6.07 ± 0.58
Pontine Tegmentum6.08 ± 0.7
Striatum6.61 ± 0.88
Subthalamus6.15 ± 0.33
Temporal Lobe5.94 ± 0.47
Thalamus5.78 ± 0.54
White Matter4.52 ± 0.28
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Eml5CBCerebellum100
100
Eml5CTXCerebral cortex100
100
Eml5HIPHippocampal region100
100
Eml5HPFHippocampal formation100
100
Eml5HYHypothalamus56.03
42.48
Eml5LSXLateral septal complex92.07
68.71
Eml5MBMidbrain68.15
59.42
Eml5MYMedulla70.66
67.69
Eml5OLFOlfactory bulb100
100
Eml5PPons59.9
55.43
Eml5PALPallidum64.19
54.83
Eml5RHPRetrohippocampal region100
95.2
Eml5sAMYStriatum-like amygdalar nuclei100
86.91
Eml5STRStriatum100
100
Eml5STRdStriatum dorsal region100
100
Eml5STRvStriatum ventral region100
100
Eml5THThalamus44.92
41.48
Peptide Top

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  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018