AutismKB 2.0

Annotation Detail for DYX1C1


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:DYX1C1 ( DYX1,DYXC1,EKN1,FLJ37882,MGC70618,RD )
Gene Full Name: dyslexia susceptibility 1 candidate 1
Band: 15q21.3
Quick LinksEntrez ID:161582; OMIM: 608706; Uniprot ID:DYXC1_HUMAN; ENSEMBL ID: ENSG00000128845; HGNC ID:
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus5 / 5640128
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult16 / 19391218
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma2 / 17475114
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor1 / 2638453
glioma2 / 10688318
head and neck tumor2 / 13630214
kidney tumor1 / 6895914
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal32 / 33603079
ovarian tumor0 / 766820 
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer1 / 1026809
retinoblastoma0 / 463560 
skin tumor1 / 1249498
soft tissue/muscle tissue tumor4 / 12519131
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder2 / 2975767
blood0 / 1234780 
bone1 / 7165513
bone marrow0 / 488010 
brain5 / 11009894
cervix0 / 481710 
connective tissue4 / 14925526
ear0 / 162120 
embryonic tissue1 / 2157224
esophagus0 / 202090 
eye1 / 2110544
heart0 / 896260 
intestine0 / 2344720 
kidney2 / 2117779
larynx0 / 241450 
liver2 / 2077439
lung7 / 33697420
lymph0 / 442700 
lymph node0 / 916100 
mammary gland2 / 15327113
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas3 / 21481213
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland1 / 1658560
placenta0 / 2808250 
prostate1 / 1893455
salivary gland0 / 201550 
skin1 / 2105744
spleen0 / 539520 
stomach1 / 9661910
testis10 / 33044230
thymus0 / 811310 
thyroid2 / 4747342
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_17036_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.17 ± 0.42
Basal Forebrain5.35 ± 0.31
Basal Part of Pons4.51 ± 0.55
Cerebellar Cortex4.37 ± 0.49
Cerebellar Nuclei3.91 ± 0.51
Claustrum4.6 ± 0.71
Epithalamus6.26 ± 0.72
Frontal Lobe4.97 ± 0.61
Globus Pallidus5.57 ± 0.4
Hypothalamus5.58 ± 0.55
Insula5.47 ± 0.37
Limbic Lobe5.26 ± 0.43
Mesencephalon5.01 ± 0.68
Myelencephalon5.04 ± 0.66
Occipital Lobe4.46 ± 0.51
Parietal Lobe4.97 ± 0.53
Pontine Tegmentum5.06 ± 0.61
Striatum5.66 ± 0.51
Subthalamus4.9 ± 0.55
Temporal Lobe5.09 ± 0.48
Thalamus4.65 ± 0.49
White Matter4.6 ± 0.27
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Dyx1c1CBCerebellum0.43
0.51
Dyx1c1CTXCerebral cortex1.4
0.96
Dyx1c1HIPHippocampal region3.18
2.76
Dyx1c1HPFHippocampal formation2.95
2.43
Dyx1c1HYHypothalamus0.11
0.28
Dyx1c1LSXLateral septal complex0.38
0.36
Dyx1c1MBMidbrain0.52
0.95
Dyx1c1MYMedulla0.66
1.11
Dyx1c1OLFOlfactory bulb2.24
1.54
Dyx1c1PPons0.53
0.89
Dyx1c1PALPallidum0.25
0.21
Dyx1c1RHPRetrohippocampal region2.65
2.04
Dyx1c1sAMYStriatum-like amygdalar nuclei0.3
0.51
Dyx1c1STRStriatum0.47
0.48
Dyx1c1STRdStriatum dorsal region0.5
0.55
Dyx1c1STRvStriatum ventral region0.51
0.29
Dyx1c1THThalamus1.12
1.23
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018