AutismKB 2.0

Annotation Detail for DBC1


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Basic Information Top
Gene Symbol:DBC1 ( DBCCR1,FAM5A )
Gene Full Name: deleted in bladder cancer 1
Band: 9q32-q33
Quick LinksEntrez ID:1620; OMIM: 602865; Uniprot ID:DBC1_HUMAN; ENSEMBL ID: ENSG00000078725; HGNC ID:
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst2 / 6231932
fetus4 / 5640127
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult22 / 193912111
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor4 / 26384515
glioma2 / 10688318
head and neck tumor2 / 13630214
kidney tumor3 / 6895943
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal45 / 336030713
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor5 / 12519139
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone1 / 7165513
bone marrow2 / 4880140
brain19 / 110098917
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue4 / 21572218
esophagus0 / 202090 
eye7 / 21105433
heart0 / 896260 
intestine0 / 2344720 
kidney6 / 21177728
larynx1 / 2414541
liver0 / 2077430 
lung1 / 3369742
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle4 / 10771537
nerve0 / 157680 
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate0 / 1893450 
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach0 / 966190 
testis4 / 33044212
thymus0 / 811310 
thyroid1 / 4747321
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus1 / 2328784
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 205818_at
Cell line Expression level Expression bar
721_B_lymphoblasts5.25
Adipocyte4.15
AdrenalCortex4.4
Adrenalgland3.6
Amygdala57.95
Appendix5.3
AtrioventricularNode3.65
BDCA4+_DentriticCells4.7
Bonemarrow4.2
BronchialEpithelialCells4.15
CD105+_Endothelial4.25
CD14+_Monocytes4.55
CD19+_BCells(neg._sel.)4.55
CD33+_Myeloid5.35
CD34+5.4
CD4+_Tcells4.6
CD56+_NKCells5.15
CD71+_EarlyErythroid3.9
CD8+_Tcells4.1
CardiacMyocytes5.3
Caudatenucleus61.65
Cerebellum24.85
CerebellumPeduncles46.1
CiliaryGanglion3
CingulateCortex132.1
Colorectaladenocarcinoma4.2
DorsalRootGanglion3.5
FetalThyroid4.1
Fetalbrain83.8
Fetalliver3.65
Fetallung3.45
GlobusPallidus44.1
Heart5.3
Hypothalamus41.3
Kidney3.55
Leukemia_chronicMyelogenousK-5623.8
Leukemia_promyelocytic-HL-603.7
Leukemialymphoblastic(MOLT-4)3.35
Liver5.85
Lung4.65
Lymphnode3.6
Lymphoma_burkitts(Daudi)5.35
Lymphoma_burkitts(Raji)5.9
MedullaOblongata87.9
OccipitalLobe74.15
OlfactoryBulb3.4
Ovary2.9
Pancreas3.35
PancreaticIslet4.5
ParietalLobe123.65
Pituitary4.95
Placenta4.35
Pons19.5
PrefrontalCortex67.75
Prostate5
Salivarygland3.4
SkeletalMuscle6.95
Skin3.3
SmoothMuscle4.8
Spinalcord52.5
SubthalamicNucleus46.15
SuperiorCervicalGanglion4.9
TemporalLobe76.4
Testis3.6
TestisGermCell3.55
TestisIntersitial4.1
TestisLeydigCell4.25
TestisSeminiferousTubule3.6
Thalamus88.25
Thymus3.35
Thyroid5.2
Tongue4.1
Tonsil4.05
Trachea3.5
TrigeminalGanglion4.65
Uterus3.45
UterusCorpus4
WholeBlood4.65
Wholebrain334.4
colon4.25
pineal_day10.92
pineal_night17.42
retina7.025
small_intestine4.05
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_16794_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.83 ± 0.47
Basal Forebrain6.4 ± 0.35
Basal Part of Pons6.08 ± 0.32
Cerebellar Cortex6.36 ± 0.21
Cerebellar Nuclei6.14 ± 0.25
Claustrum6.87 ± 0.63
Epithalamus5.85 ± 0.28
Frontal Lobe6.4 ± 0.32
Globus Pallidus6.29 ± 0.33
Hypothalamus6.24 ± 0.26
Insula6.31 ± 0.2
Limbic Lobe6.72 ± 0.43
Mesencephalon6.51 ± 0.41
Myelencephalon6.56 ± 0.43
Occipital Lobe7.11 ± 0.45
Parietal Lobe6.66 ± 0.33
Pontine Tegmentum6.59 ± 0.23
Striatum6.76 ± 0.42
Subthalamus5.96 ± 0.58
Temporal Lobe6.51 ± 0.35
Thalamus6.73 ± 0.33
White Matter5.35 ± 0.4
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Dbc1HYHypothalamus77.12
75.44
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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