AutismKB 2.0

Annotation Detail for SLFN5


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Basic Information Top
Gene Symbol:SLFN5 ( MGC150611,MGC150612,MGC19764 )
Gene Full Name: schlafen family member 5
Band: 17q12
Quick LinksEntrez ID:162394; OMIM: NA; Uniprot ID:SLFN5_HUMAN; ENSEMBL ID: ENSG00000166750; HGNC ID: 28286
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body5 / 7076170
blastocyst0 / 623190 
fetus10 / 56401217
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult39 / 193912120
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_13508_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.64 ± 0.7
Basal Forebrain4.25 ± 0.55
Basal Part of Pons4.67 ± 0.47
Cerebellar Cortex4.2 ± 0.42
Cerebellar Nuclei4.73 ± 0.63
Claustrum4.32 ± 0.76
Epithalamus4.67 ± 0.4
Frontal Lobe4.41 ± 0.54
Globus Pallidus5.52 ± 0.24
Hypothalamus4.19 ± 0.74
Insula4.38 ± 0.42
Limbic Lobe4.69 ± 0.55
Mesencephalon4.51 ± 0.66
Myelencephalon4.59 ± 0.57
Occipital Lobe4.74 ± 0.54
Parietal Lobe4.61 ± 0.53
Pontine Tegmentum4.42 ± 0.55
Striatum4.51 ± 0.53
Subthalamus4.25 ± 0.48
Temporal Lobe4.43 ± 0.47
Thalamus4.56 ± 0.47
White Matter6.27 ± 0.46
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Slfn5CBCerebellum25.22
27.17
Slfn5CTXCerebral cortex80.87
58.97
Slfn5HIPHippocampal region37.59
44.57
Slfn5HPFHippocampal formation42.43
41.53
Slfn5HYHypothalamus36.73
27.42
Slfn5LSXLateral septal complex25.66
17.87
Slfn5MBMidbrain35.86
28.93
Slfn5MYMedulla37.11
34.58
Slfn5OLFOlfactory bulb69.55
56.09
Slfn5PPons38.59
32.7
Slfn5PALPallidum31.72
26.04
Slfn5RHPRetrohippocampal region51.71
38.33
Slfn5sAMYStriatum-like amygdalar nuclei34.36
24.89
Slfn5STRStriatum34.49
24.99
Slfn5STRdStriatum dorsal region31.64
22.51
Slfn5STRvStriatum ventral region50.8
37.21
Slfn5THThalamus52.03
39.86
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00487100 12 72 83 HGVGLDVPPIFR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018