AutismKB 2.0

Annotation Detail for SLFN5


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Basic Information Top
Gene Symbol:SLFN5 ( MGC150611,MGC150612,MGC19764 )
Gene Full Name: schlafen family member 5
Band: 17q12
Quick LinksEntrez ID:162394; OMIM: NA; Uniprot ID:SLFN5_HUMAN; ENSEMBL ID: ENSG00000166750; HGNC ID: 28286
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body5 / 7076170
blastocyst0 / 623190 
fetus10 / 56401217
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult39 / 193912120
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor1 / 3436629
chondrosarcoma3 / 8282336
colorectal tumor3 / 11424626
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor4 / 26384515
glioma4 / 10688337
head and neck tumor10 / 13630273
kidney tumor1 / 6895914
leukemia1 / 9584210
liver tumor1 / 9635910
lung tumor2 / 10312719
lymphoma0 / 717550 
non-neoplasia1 / 9725010
normal62 / 336030718
ovarian tumor2 / 7668226
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor4 / 12494932
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites0 / 400150 
bladder0 / 297570 
blood1 / 1234788
bone3 / 7165541
bone marrow0 / 488010 
brain16 / 110098914
cervix1 / 4817120
connective tissue3 / 14925520
ear0 / 162120 
embryonic tissue6 / 21572227
esophagus0 / 202090 
eye1 / 2110544
heart1 / 8962611
intestine4 / 23447217
kidney3 / 21177714
larynx1 / 2414541
liver3 / 20774314
lung4 / 33697411
lymph0 / 442700 
lymph node1 / 9161010
mammary gland6 / 15327139
mouth8 / 67052119
muscle5 / 10771546
nerve0 / 157680 
ovary2 / 10205119
pancreas1 / 2148124
parathyroid0 / 205390 
pharynx4 / 4132896
pituitary gland0 / 165850 
placenta9 / 28082532
prostate3 / 18934515
salivary gland0 / 201550 
skin5 / 21057423
spleen1 / 5395218
stomach3 / 9661931
testis1 / 3304423
thymus8 / 8113198
thyroid1 / 4747321
tonsil0 / 169990 
trachea4 / 5241376
umbilical cord1 / 1368073
uterus0 / 2328780 
vascular1 / 5178019
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_13508_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.64 ± 0.7
Basal Forebrain4.25 ± 0.55
Basal Part of Pons4.67 ± 0.47
Cerebellar Cortex4.2 ± 0.42
Cerebellar Nuclei4.73 ± 0.63
Claustrum4.32 ± 0.76
Epithalamus4.67 ± 0.4
Frontal Lobe4.41 ± 0.54
Globus Pallidus5.52 ± 0.24
Hypothalamus4.19 ± 0.74
Insula4.38 ± 0.42
Limbic Lobe4.69 ± 0.55
Mesencephalon4.51 ± 0.66
Myelencephalon4.59 ± 0.57
Occipital Lobe4.74 ± 0.54
Parietal Lobe4.61 ± 0.53
Pontine Tegmentum4.42 ± 0.55
Striatum4.51 ± 0.53
Subthalamus4.25 ± 0.48
Temporal Lobe4.43 ± 0.47
Thalamus4.56 ± 0.47
White Matter6.27 ± 0.46
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Slfn5CBCerebellum25.22
27.17
Slfn5CTXCerebral cortex80.87
58.97
Slfn5HIPHippocampal region37.59
44.57
Slfn5HPFHippocampal formation42.43
41.53
Slfn5HYHypothalamus36.73
27.42
Slfn5LSXLateral septal complex25.66
17.87
Slfn5MBMidbrain35.86
28.93
Slfn5MYMedulla37.11
34.58
Slfn5OLFOlfactory bulb69.55
56.09
Slfn5PPons38.59
32.7
Slfn5PALPallidum31.72
26.04
Slfn5RHPRetrohippocampal region51.71
38.33
Slfn5sAMYStriatum-like amygdalar nuclei34.36
24.89
Slfn5STRStriatum34.49
24.99
Slfn5STRdStriatum dorsal region31.64
22.51
Slfn5STRvStriatum ventral region50.8
37.21
Slfn5THThalamus52.03
39.86
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00487100 12 72 83 HGVGLDVPPIFR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018