Annotation Detail for DENND2C
Basic Information Top
| Gene Symbol: | DENND2C ( DKFZp686G0351,DKFZp686N1631,DKFZp779P1149,FLJ37099,dJ1156J9.1 ) |
|---|---|
| Gene Full Name: | DENN/MADD domain containing 2C |
| Band: | 1p13.2 |
| Quick Links | Entrez ID:163259; OMIM: NA; Uniprot ID:DEN2C_HUMAN; ENSEMBL ID: ENSG00000175984; HGNC ID: 24748 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.654928
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 0 / 70761 | 0 | |
| blastocyst | 2 / 62319 | 32 |  |
| fetus | 6 / 564012 | 10 |  |
| neonate | 0 / 31097 | 0 | |
| infant | 0 / 23620 | 0 | |
| juvenile | 0 / 55556 | 0 | |
| adult | 11 / 1939121 | 5 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 0 / 17475 | 0 | |
| breast (mammary gland) tumor | 0 / 94178 | 0 | |
| cervical tumor | 0 / 34366 | 0 | |
| chondrosarcoma | 0 / 82823 | 0 | |
| colorectal tumor | 1 / 114246 | 8 | |
| esophageal tumor | 0 / 17290 | 0 | |
| gastrointestinal tumor | 0 / 119369 | 0 | |
| germ cell tumor | 0 / 263845 | 0 | |
| glioma | 0 / 106883 | 0 | |
| head and neck tumor | 1 / 136302 | 7 | |
| kidney tumor | 0 / 68959 | 0 | |
| leukemia | 0 / 95842 | 0 | |
| liver tumor | 3 / 96359 | 31 | |
| lung tumor | 3 / 103127 | 29 | |
| lymphoma | 0 / 71755 | 0 | |
| non-neoplasia | 0 / 97250 | 0 | |
| normal | 32 / 3360307 | 9 | |
| ovarian tumor | 0 / 76682 | 0 | |
| pancreatic tumor | 0 / 104616 | 0 | |
| primitive neuroectodermal tumor of the CNS | 0 / 125680 | 0 | |
| prostate cancer | 0 / 102680 | 0 | |
| retinoblastoma | 0 / 46356 | 0 | |
| skin tumor | 0 / 124949 | 0 | |
| soft tissue/muscle tissue tumor | 0 / 125191 | 0 | |
| uterine tumor | 0 / 90257 | 0 |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 0 / 13106 | 0 | |
| adrenal gland | 0 / 33197 | 0 | |
| ascites | 0 / 40015 | 0 | |
| bladder | 0 / 29757 | 0 | |
| blood | 0 / 123478 | 0 | |
| bone | 0 / 71655 | 0 | |
| bone marrow | 0 / 48801 | 0 | |
| brain | 2 / 1100989 | 1 |  |
| cervix | 0 / 48171 | 0 | |
| connective tissue | 0 / 149255 | 0 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 2 / 215722 | 9 | |
| esophagus | 0 / 20209 | 0 | |
| eye | 1 / 211054 | 4 | |
| heart | 2 / 89626 | 22 | |
| intestine | 1 / 234472 | 4 | |
| kidney | 1 / 211777 | 4 | |
| larynx | 1 / 24145 | 41 | |
| liver | 5 / 207743 | 24 | |
| lung | 4 / 336974 | 11 | |
| lymph | 0 / 44270 | 0 | |
| lymph node | 0 / 91610 | 0 | |
| mammary gland | 0 / 153271 | 0 | |
| mouth | 1 / 67052 | 14 | |
| muscle | 3 / 107715 | 27 | |
| nerve | 0 / 15768 | 0 | |
| ovary | 0 / 102051 | 0 | |
| pancreas | 0 / 214812 | 0 | |
| parathyroid | 0 / 20539 | 0 | |
| pharynx | 0 / 41328 | 0 | |
| pituitary gland | 0 / 16585 | 0 | |
| placenta | 0 / 280825 | 0 | |
| prostate | 2 / 189345 | 10 | |
| salivary gland | 0 / 20155 | 0 | |
| skin | 3 / 210574 | 14 | |
| spleen | 0 / 53952 | 0 | |
| stomach | 0 / 96619 | 0 | |
| testis | 9 / 330442 | 27 | |
| thymus | 0 / 81131 | 0 | |
| thyroid | 0 / 47473 | 0 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 0 / 52413 | 0 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 0 / 232878 | 0 | |
| vascular | 0 / 51780 | 0 |
Microarray in - Probe name: A_24_P247006
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 4.57 ± 0.63 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 4.51 ± 0.28 | |
| Basal Part of Pons | 4.05 ± 0.44 | |
| Cerebellar Cortex | 4.85 ± 0.42 | |
| Cerebellar Nuclei | 4.9 ± 0.62 | |
| Claustrum | 4.58 ± 0.63 | |
| Epithalamus | 5.08 ± 0.39 | |
| Frontal Lobe | 4.37 ± 0.66 | |
| Globus Pallidus | 5.05 ± 0.52 | |
| Hypothalamus | 4.35 ± 0.4 | |
| Insula | 4.69 ± 0.43 | |
| Limbic Lobe | 4.67 ± 0.89 | |
| Mesencephalon | 4.7 ± 0.7 | |
| Myelencephalon | 4.5 ± 0.63 | |
| Occipital Lobe | 4.35 ± 0.69 | |
| Parietal Lobe | 4.26 ± 0.72 | |
| Pontine Tegmentum | 4.65 ± 0.71 | |
| Striatum | 5.47 ± 0.69 | |
| Subthalamus | 4.71 ± 0.41 | |
| Temporal Lobe | 4.43 ± 0.54 | |
| Thalamus | 4.42 ± 0.48 | |
| White Matter | 5.38 ± 0.37 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Dennd2c | CB | Cerebellum | 6.24 |  |
| 6.57 | | |||
| Dennd2c | CTX | Cerebral cortex | 7.42 | |
| 5.57 | | |||
| Dennd2c | HIP | Hippocampal region | 2.49 | |
| 2.16 | | |||
| Dennd2c | HPF | Hippocampal formation | 3.42 | |
| 2.65 | | |||
| Dennd2c | HY | Hypothalamus | 4.82 | |
| 3.47 | | |||
| Dennd2c | LSX | Lateral septal complex | 2.37 | |
| 1.61 | | |||
| Dennd2c | MB | Midbrain | 7.06 | |
| 6.16 | | |||
| Dennd2c | MY | Medulla | 14.98 | |
| 14.36 | | |||
| Dennd2c | OLF | Olfactory bulb | 8.81 | |
| 6.02 | | |||
| Dennd2c | P | Pons | 12.64 | |
| 12.39 | | |||
| Dennd2c | PAL | Pallidum | 5.64 | |
| 4.73 | | |||
| Dennd2c | RHP | Retrohippocampal region | 5.32 | |
| 3.54 | | |||
| Dennd2c | sAMY | Striatum-like amygdalar nuclei | 4.81 | |
| 3.27 | | |||
| Dennd2c | STR | Striatum | 2.95 | |
| 1.94 | | |||
| Dennd2c | STRd | Striatum dorsal region | 2.45 | |
| 1.68 | | |||
| Dennd2c | STRv | Striatum ventral region | 3.74 | |
| 2.11 | | |||
| Dennd2c | TH | Thalamus | 6.83 | |
| 6.16 | |