AutismKB 2.0

Annotation Detail for DCN


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Basic Information Top
Gene Symbol:DCN ( CSCD,DSPG2,PG40,PGII,PGS2,SLRR1B )
Gene Full Name: decorin
Band: 12q21.33
Quick LinksEntrez ID:1634; OMIM: 125255; Uniprot ID:PGS2_HUMAN; ENSEMBL ID: ENSG00000011465; HGNC ID: 2705
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 211813_x_at
Cell line Expression level Expression bar
721_B_lymphoblasts5.8
Adipocyte6034.7
AdrenalCortex1194.9
Adrenalgland607
Amygdala55.95
Appendix2345.75
AtrioventricularNode1842.55
BDCA4+_DentriticCells4.85
Bonemarrow47.4
BronchialEpithelialCells5.3
CD105+_Endothelial7.3
CD14+_Monocytes4.65
CD19+_BCells(neg._sel.)5
CD33+_Myeloid5.75
CD34+5.45
CD4+_Tcells4.9
CD56+_NKCells5.15
CD71+_EarlyErythroid9.3
CD8+_Tcells4.35
CardiacMyocytes899.6
Caudatenucleus32.1
Cerebellum14.1
CerebellumPeduncles23.25
CiliaryGanglion2064.4
CingulateCortex20.2
Colorectaladenocarcinoma6
DorsalRootGanglion854.65
FetalThyroid1006.15
Fetalbrain61.35
Fetalliver152.6
Fetallung1289.3
GlobusPallidus19.1
Heart158.6
Hypothalamus76.95
Kidney157.8
Leukemia_chronicMyelogenousK-56212.5
Leukemia_promyelocytic-HL-604.45
Leukemialymphoblastic(MOLT-4)7
Liver124.2
Lung609.55
Lymphnode714.8
Lymphoma_burkitts(Daudi)11.3
Lymphoma_burkitts(Raji)6.55
MedullaOblongata34.8
OccipitalLobe63.55
OlfactoryBulb790.75
Ovary2265.4
Pancreas135.35
PancreaticIslet201.3
ParietalLobe20.7
Pituitary155.4
Placenta1672.85
Pons100.35
PrefrontalCortex80.6
Prostate147
Salivarygland529.55
SkeletalMuscle381.3
Skin732.55
SmoothMuscle1125.55
Spinalcord216.95
SubthalamicNucleus41.25
SuperiorCervicalGanglion657.45
TemporalLobe45.6
Testis133.15
TestisGermCell1334.9
TestisIntersitial1067.9
TestisLeydigCell955.95
TestisSeminiferousTubule507.6
Thalamus79.85
Thymus298.5
Thyroid510.85
Tongue1111.75
Tonsil412.8
Trachea1403.85
TrigeminalGanglion1442.4
Uterus1573.6
UterusCorpus1268.85
WholeBlood11.95
Wholebrain32.45
colon603.3
pineal_day185.06
pineal_night287.48
retina676.825
small_intestine689
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_14983_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.37 ± 0.53
Basal Forebrain6.28 ± 0.19
Basal Part of Pons5.85 ± 0.47
Cerebellar Cortex5.99 ± 0.43
Cerebellar Nuclei7.29 ± 0.41
Claustrum5.95 ± 0.6
Epithalamus6.37 ± 0.81
Frontal Lobe6.39 ± 0.56
Globus Pallidus7.6 ± 0.37
Hypothalamus6.36 ± 0.58
Insula6.56 ± 0.48
Limbic Lobe6.39 ± 0.69
Mesencephalon6.57 ± 0.5
Myelencephalon6.58 ± 0.52
Occipital Lobe6.26 ± 0.51
Parietal Lobe6.31 ± 0.54
Pontine Tegmentum6.76 ± 0.51
Striatum7.24 ± 0.5
Subthalamus6.55 ± 0.36
Temporal Lobe6.48 ± 0.49
Thalamus6.69 ± 0.38
White Matter6.58 ± 0.67
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
DcnCBCerebellum7.38
28.38
DcnCTXCerebral cortex2.96
5.48
DcnHIPHippocampal region9.97
27.68
DcnHPFHippocampal formation16.88
46.48
DcnHYHypothalamus3.5
9.8
DcnLSXLateral septal complex3.99
11.27
DcnMBMidbrain8.68
25.55
DcnMYMedulla9.68
28.18
DcnOLFOlfactory bulb6.45
11.19
DcnPPons7.31
21.37
DcnPALPallidum3.86
10.62
DcnRHPRetrohippocampal region28.07
72.27
DcnsAMYStriatum-like amygdalar nuclei5.6
12.38
DcnSTRStriatum2.73
5.84
DcnSTRdStriatum dorsal region2.25
4.71
DcnSTRvStriatum ventral region2.38
4.2
DcnTHThalamus5.17
16.12
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00081119 14 64 77 VVQCSDLGLDKVPK Peptide Atlas
PGS2_HUMAN_120 11 120 130 VSPGAFTPLVK PRIDE
PGS2_HUMAN_64 11 64 74 VVQCSDLGLDK PRIDE
PGS2_HUMAN_78 15 78 92 DLPPDTTLLDLQNNK PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018