Annotation Detail for DENND1B
Basic Information Top
| Gene Symbol: | DENND1B ( C1ORF18,C1orf218,DKFZp547O0715,FAM31B,FLJ20054,FLJ21179,FLJ33888,MGC103810,MGC27044 ) |
|---|---|
| Gene Full Name: | DENN/MADD domain containing 1B |
| Band: | 1q31.3 |
| Quick Links | Entrez ID:163486; OMIM: 613292; Uniprot ID:DEN1B_HUMAN; ENSEMBL ID: ENSG00000213047; HGNC ID: 28404 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.125056
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 3 / 70761 | 42 |  |
| blastocyst | 0 / 62319 | 0 | |
| fetus | 16 / 564012 | 28 | |
| neonate | 0 / 31097 | 0 | |
| infant | 0 / 23620 | 0 | |
| juvenile | 0 / 55556 | 0 | |
| adult | 46 / 1939121 | 23 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 1 / 17475 | 57 |  |
| breast (mammary gland) tumor | 2 / 94178 | 21 | |
| cervical tumor | 0 / 34366 | 0 | |
| chondrosarcoma | 0 / 82823 | 0 | |
| colorectal tumor | 0 / 114246 | 0 | |
| esophageal tumor | 1 / 17290 | 57 | |
| gastrointestinal tumor | 2 / 119369 | 16 | |
| germ cell tumor | 1 / 263845 | 3 |  |
| glioma | 0 / 106883 | 0 | |
| head and neck tumor | 3 / 136302 | 22 | |
| kidney tumor | 0 / 68959 | 0 | |
| leukemia | 0 / 95842 | 0 | |
| liver tumor | 3 / 96359 | 31 | |
| lung tumor | 0 / 103127 | 0 | |
| lymphoma | 2 / 71755 | 27 | |
| non-neoplasia | 2 / 97250 | 20 | |
| normal | 73 / 3360307 | 21 | |
| ovarian tumor | 2 / 76682 | 26 | |
| pancreatic tumor | 1 / 104616 | 9 | |
| primitive neuroectodermal tumor of the CNS | 1 / 125680 | 7 | |
| prostate cancer | 3 / 102680 | 29 | |
| retinoblastoma | 0 / 46356 | 0 | |
| skin tumor | 0 / 124949 | 0 | |
| soft tissue/muscle tissue tumor | 3 / 125191 | 23 | |
| uterine tumor | 2 / 90257 | 22 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 0 / 13106 | 0 | |
| adrenal gland | 0 / 33197 | 0 | |
| ascites | 0 / 40015 | 0 | |
| bladder | 3 / 29757 | 100 | |
| blood | 4 / 123478 | 32 | |
| bone | 0 / 71655 | 0 | |
| bone marrow | 5 / 48801 | 102 | |
| brain | 10 / 1100989 | 9 | |
| cervix | 0 / 48171 | 0 | |
| connective tissue | 5 / 149255 | 33 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 4 / 215722 | 18 | |
| esophagus | 1 / 20209 | 49 | |
| eye | 1 / 211054 | 4 | |
| heart | 0 / 89626 | 0 | |
| intestine | 4 / 234472 | 17 | |
| kidney | 6 / 211777 | 28 | |
| larynx | 0 / 24145 | 0 | |
| liver | 5 / 207743 | 24 | |
| lung | 1 / 336974 | 2 | |
| lymph | 2 / 44270 | 45 | |
| lymph node | 9 / 91610 | 98 | |
| mammary gland | 4 / 153271 | 26 | |
| mouth | 3 / 67052 | 44 | |
| muscle | 5 / 107715 | 46 | |
| nerve | 1 / 15768 | 63 | |
| ovary | 3 / 102051 | 29 | |
| pancreas | 1 / 214812 | 4 | |
| parathyroid | 2 / 20539 | 97 | |
| pharynx | 1 / 41328 | 24 | |
| pituitary gland | 0 / 16585 | 0 | |
| placenta | 5 / 280825 | 17 | |
| prostate | 4 / 189345 | 21 | |
| salivary gland | 0 / 20155 | 0 | |
| skin | 0 / 210574 | 0 | |
| spleen | 0 / 53952 | 0 | |
| stomach | 6 / 96619 | 62 | |
| testis | 3 / 330442 | 9 | |
| thymus | 6 / 81131 | 73 | |
| thyroid | 1 / 47473 | 21 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 0 / 52413 | 0 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 4 / 232878 | 17 | |
| vascular | 3 / 51780 | 57 | |
Microarray in - Probe name: CUST_9233_PI416261804
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 4.63 ± 0.35 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 4.34 ± 0.38 | |
| Basal Part of Pons | 3.85 ± 0.61 | |
| Cerebellar Cortex | 4.14 ± 0.37 | |
| Cerebellar Nuclei | 4.11 ± 0.56 | |
| Claustrum | 4.22 ± 0.77 | |
| Epithalamus | 4.67 ± 0.38 | |
| Frontal Lobe | 4.23 ± 0.49 | |
| Globus Pallidus | 4.75 ± 0.3 | |
| Hypothalamus | 4.12 ± 0.59 | |
| Insula | 4.37 ± 0.19 | |
| Limbic Lobe | 4.28 ± 0.53 | |
| Mesencephalon | 4.51 ± 0.58 | |
| Myelencephalon | 4.38 ± 0.53 | |
| Occipital Lobe | 4.72 ± 0.5 | |
| Parietal Lobe | 4.44 ± 0.47 | |
| Pontine Tegmentum | 4.44 ± 0.51 | |
| Striatum | 5.55 ± 0.38 | |
| Subthalamus | 4.1 ± 0.37 | |
| Temporal Lobe | 4.3 ± 0.41 | |
| Thalamus | 4.41 ± 0.44 | |
| White Matter | 3.24 ± 0.24 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| BC042698 | CB | Cerebellum | 4.12 | |
| 3.8 | | |||
| BC042698 | CTX | Cerebral cortex | 8.52 | |
| 5.5 | | |||
| BC042698 | HIP | Hippocampal region | 13.62 | |
| 12.25 | | |||
| BC042698 | HPF | Hippocampal formation | 14.7 | |
| 11.5 | | |||
| BC042698 | HY | Hypothalamus | 17.72 | |
| 11.8 | | |||
| BC042698 | LSX | Lateral septal complex | 4.09 | |
| 2.29 | | |||
| BC042698 | MB | Midbrain | 19.19 | |
| 14.21 | | |||
| BC042698 | MY | Medulla | 18.19 | |
| 14.92 | | |||
| BC042698 | OLF | Olfactory bulb | 11.21 | |
| 9.93 | | |||
| BC042698 | P | Pons | 19.31 | |
| 15.02 | | |||
| BC042698 | PAL | Pallidum | 15 | |
| 11.27 | | |||
| BC042698 | RHP | Retrohippocampal region | 17.36 | |
| 10.89 | | |||
| BC042698 | sAMY | Striatum-like amygdalar nuclei | 9.19 | |
| 5.78 | | |||
| BC042698 | STR | Striatum | 3.44 | |
| 2.22 | | |||
| BC042698 | STRd | Striatum dorsal region | 1.74 | |
| 1.16 | | |||
| BC042698 | STRv | Striatum ventral region | 6.5 | |
| 4.07 | | |||
| BC042698 | TH | Thalamus | 13.4 | |
| 9.09 | |