AutismKB 2.0

Annotation Detail for DCTD


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Basic Information Top
Gene Symbol:DCTD ( MGC111062 )
Gene Full Name: dCMP deaminase
Band: 4q35.1
Quick LinksEntrez ID:1635; OMIM: 607638; Uniprot ID:DCTD_HUMAN; ENSEMBL ID: ENSG00000129187; HGNC ID: 2710
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body6 / 7076184
blastocyst4 / 6231964
fetus43 / 56401276
neonate4 / 31097128
infant1 / 2362042
juvenile1 / 5555617
adult186 / 193912195
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor18 / 94178191
cervical tumor8 / 34366232
chondrosarcoma12 / 82823144
colorectal tumor12 / 114246105
esophageal tumor6 / 17290347
gastrointestinal tumor17 / 119369142
germ cell tumor11 / 26384541
glioma14 / 106883130
head and neck tumor5 / 13630236
kidney tumor6 / 6895987
leukemia7 / 9584273
liver tumor11 / 96359114
lung tumor7 / 10312767
lymphoma2 / 7175527
non-neoplasia16 / 97250164
normal255 / 336030775
ovarian tumor6 / 7668278
pancreatic tumor16 / 104616152
primitive neuroectodermal tumor of the CNS14 / 125680111
prostate cancer14 / 102680136
retinoblastoma4 / 4635686
skin tumor9 / 12494972
soft tissue/muscle tissue tumor6 / 12519147
uterine tumor13 / 90257144
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue2 / 13106152
adrenal gland7 / 33197210
ascites4 / 4001599
bladder0 / 297570 
blood9 / 12347872
bone15 / 71655209
bone marrow0 / 488010 
brain68 / 110098961
cervix11 / 48171228
connective tissue19 / 149255127
ear1 / 1621261
embryonic tissue19 / 21572288
esophagus6 / 20209296
eye25 / 211054118
heart11 / 89626122
intestine21 / 23447289
kidney18 / 21177784
larynx0 / 241450 
liver14 / 20774367
lung21 / 33697462
lymph2 / 4427045
lymph node4 / 9161043
mammary gland23 / 153271150
mouth1 / 6705214
muscle2 / 10771518
nerve1 / 1576863
ovary8 / 10205178
pancreas23 / 214812107
parathyroid2 / 2053997
pharynx4 / 4132896
pituitary gland1 / 1658560
placenta9 / 28082532
prostate31 / 189345163
salivary gland1 / 2015549
skin17 / 21057480
spleen4 / 5395274
stomach12 / 96619124
testis16 / 33044248
thymus2 / 8113124
thyroid5 / 47473105
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord2 / 13680146
uterus25 / 232878107
vascular3 / 5178057
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 201571_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts132.3
Adipocyte24.7
AdrenalCortex5.7
Adrenalgland12.2
Amygdala15.5
Appendix5.4
AtrioventricularNode4.1
BDCA4+_DentriticCells53.9
Bonemarrow4.8
BronchialEpithelialCells40.2
CD105+_Endothelial5.55
CD14+_Monocytes17.45
CD19+_BCells(neg._sel.)35.65
CD33+_Myeloid20.25
CD34+24.85
CD4+_Tcells44.25
CD56+_NKCells23.85
CD71+_EarlyErythroid4.3
CD8+_Tcells24.6
CardiacMyocytes22.9
Caudatenucleus4.75
Cerebellum4.05
CerebellumPeduncles5.4
CiliaryGanglion3.65
CingulateCortex5
Colorectaladenocarcinoma35.1
DorsalRootGanglion4.15
FetalThyroid5.1
Fetalbrain4.9
Fetalliver9.1
Fetallung4.8
GlobusPallidus4.15
Heart9.8
Hypothalamus5.9
Kidney6.85
Leukemia_chronicMyelogenousK-5626.3
Leukemia_promyelocytic-HL-6021.2
Leukemialymphoblastic(MOLT-4)11
Liver32.65
Lung43.2
Lymphnode5.65
Lymphoma_burkitts(Daudi)6.45
Lymphoma_burkitts(Raji)18.6
MedullaOblongata4.6
OccipitalLobe4.85
OlfactoryBulb5
Ovary3.6
Pancreas4.45
PancreaticIslet16.9
ParietalLobe5.65
Pituitary9
Placenta10.9
Pons5.1
PrefrontalCortex5.9
Prostate19.7
Salivarygland4.3
SkeletalMuscle6.2
Skin4.15
SmoothMuscle49.2
Spinalcord5.3
SubthalamicNucleus4.9
SuperiorCervicalGanglion6.1
TemporalLobe4.9
Testis5.25
TestisGermCell4.55
TestisIntersitial3.95
TestisLeydigCell4.6
TestisSeminiferousTubule4.5
Thalamus4.85
Thymus8.85
Thyroid71.2
Tongue5.3
Tonsil5.35
Trachea4.55
TrigeminalGanglion5.35
Uterus7.1
UterusCorpus4.9
WholeBlood5.45
Wholebrain15.65
colon14.2
pineal_day6.54
pineal_night6.14
retina13.85
small_intestine14.8
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P345948
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.14 ± 0.29
Basal Forebrain7.02 ± 0.16
Basal Part of Pons7.25 ± 0.23
Cerebellar Cortex6.78 ± 0.18
Cerebellar Nuclei7.2 ± 0.29
Claustrum6.75 ± 0.45
Epithalamus7.18 ± 0.16
Frontal Lobe7.2 ± 0.3
Globus Pallidus7.49 ± 0.39
Hypothalamus7.52 ± 0.24
Insula7.28 ± 0.23
Limbic Lobe7.04 ± 0.39
Mesencephalon7.07 ± 0.32
Myelencephalon7.07 ± 0.41
Occipital Lobe6.63 ± 0.41
Parietal Lobe7.13 ± 0.34
Pontine Tegmentum7.02 ± 0.28
Striatum7 ± 0.35
Subthalamus7.36 ± 0.47
Temporal Lobe7.25 ± 0.33
Thalamus6.9 ± 0.31
White Matter7.15 ± 0.08
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
DctdCBCerebellum4.06
4.16
DctdCTXCerebral cortex1.79
1.33
DctdHIPHippocampal region3.06
2.8
DctdHPFHippocampal formation3.72
3.24
DctdHYHypothalamus2.86
2.33
DctdLSXLateral septal complex1.04
0.62
DctdMBMidbrain1.82
1.96
DctdMYMedulla7.17
7.62
DctdOLFOlfactory bulb3.26
3.62
DctdPPons5.07
6.52
DctdPALPallidum1.47
1.13
DctdRHPRetrohippocampal region5.39
4.41
DctdsAMYStriatum-like amygdalar nuclei1.25
1
DctdSTRStriatum1.04
0.82
DctdSTRdStriatum dorsal region0.36
0.24
DctdSTRvStriatum ventral region3.12
2.55
DctdTHThalamus3.13
2.69
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
DCTD_HUMAN_142 11 142 152 LLFNMAGVTFR PRIDE
DCTD_HUMAN_143 11 143 153 LLFNMAGVTFR PRIDE
DCTD_HUMAN_161 15 161 175 IVIDFDSINSRPSQK PRIDE
DCTD_HUMAN_2 8 2 9 SEVSCKKR PRIDE
DCTD_HUMAN_29 18 29 46 SKDPNSQVGACIVNSENK PRIDE
PAp00042538 18 30 47 SKDPNSQVGACIVNSENK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018