Annotation Detail for ACE
Basic Information Top
| Gene Symbol: | ACE ( ACE1,CD143,DCP,DCP1,MGC26566,MVCD3 ) |
|---|---|
| Gene Full Name: | angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 |
| Band: | 17q23.3 |
| Quick Links | Entrez ID:1636; OMIM: 106180; Uniprot ID:ACE_HUMAN; ENSEMBL ID: ENSG00000159640; HGNC ID: 2707 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.298469
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 0 / 70761 | 0 | |
| blastocyst | 0 / 62319 | 0 | |
| fetus | 13 / 564012 | 23 |  |
| neonate | 1 / 31097 | 32 | |
| infant | 0 / 23620 | 0 | |
| juvenile | 1 / 55556 | 17 | |
| adult | 106 / 1939121 | 54 |  |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 1 / 17475 | 57 | |
| breast (mammary gland) tumor | 0 / 94178 | 0 | |
| cervical tumor | 0 / 34366 | 0 | |
| chondrosarcoma | 1 / 82823 | 12 | |
| colorectal tumor | 0 / 114246 | 0 | |
| esophageal tumor | 1 / 17290 | 57 | |
| gastrointestinal tumor | 3 / 119369 | 25 | |
| germ cell tumor | 12 / 263845 | 45 | |
| glioma | 7 / 106883 | 65 | |
| head and neck tumor | 2 / 136302 | 14 | |
| kidney tumor | 1 / 68959 | 14 | |
| leukemia | 3 / 95842 | 31 | |
| liver tumor | 0 / 96359 | 0 | |
| lung tumor | 11 / 103127 | 106 | |
| lymphoma | 7 / 71755 | 97 | |
| non-neoplasia | 2 / 97250 | 20 | |
| normal | 139 / 3360307 | 41 | |
| ovarian tumor | 0 / 76682 | 0 | |
| pancreatic tumor | 3 / 104616 | 28 | |
| primitive neuroectodermal tumor of the CNS | 22 / 125680 | 175 | |
| prostate cancer | 0 / 102680 | 0 | |
| retinoblastoma | 1 / 46356 | 21 | |
| skin tumor | 0 / 124949 | 0 | |
| soft tissue/muscle tissue tumor | 2 / 125191 | 15 | |
| uterine tumor | 4 / 90257 | 44 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 1 / 13106 | 76 | |
| adrenal gland | 0 / 33197 | 0 | |
| ascites | 0 / 40015 | 0 | |
| bladder | 1 / 29757 | 33 | |
| blood | 1 / 123478 | 8 |  |
| bone | 0 / 71655 | 0 | |
| bone marrow | 0 / 48801 | 0 | |
| brain | 74 / 1100989 | 67 | |
| cervix | 1 / 48171 | 20 | |
| connective tissue | 2 / 149255 | 13 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 0 / 215722 | 0 | |
| esophagus | 1 / 20209 | 49 | |
| eye | 4 / 211054 | 18 | |
| heart | 4 / 89626 | 44 | |
| intestine | 7 / 234472 | 29 | |
| kidney | 12 / 211777 | 56 | |
| larynx | 0 / 24145 | 0 | |
| liver | 0 / 207743 | 0 | |
| lung | 23 / 336974 | 68 | |
| lymph | 3 / 44270 | 67 | |
| lymph node | 0 / 91610 | 0 | |
| mammary gland | 5 / 153271 | 32 | |
| mouth | 1 / 67052 | 14 | |
| muscle | 1 / 107715 | 9 | |
| nerve | 0 / 15768 | 0 | |
| ovary | 0 / 102051 | 0 | |
| pancreas | 7 / 214812 | 32 | |
| parathyroid | 3 / 20539 | 146 | |
| pharynx | 1 / 41328 | 24 | |
| pituitary gland | 0 / 16585 | 0 | |
| placenta | 7 / 280825 | 24 | |
| prostate | 11 / 189345 | 58 | |
| salivary gland | 0 / 20155 | 0 | |
| skin | 0 / 210574 | 0 | |
| spleen | 0 / 53952 | 0 | |
| stomach | 3 / 96619 | 31 | |
| testis | 16 / 330442 | 48 | |
| thymus | 1 / 81131 | 12 | |
| thyroid | 0 / 47473 | 0 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 0 / 52413 | 0 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 4 / 232878 | 17 | |
| vascular | 2 / 51780 | 38 | |
- Microarray Platform: GeneAtlas U133A, gcrma
- Affymatrix Probe ID: 209749_s_at
| Cell line | Expression level | Expression bar |
|---|---|---|
| ||
| 721_B_lymphoblasts | 6.85 | |
| Adipocyte | 7.3 | |
| AdrenalCortex | 6.7 | |
| Adrenalgland | 5.35 | |
| Amygdala | 6.2 | |
| Appendix | 6.35 | |
| AtrioventricularNode | 5.05 | |
| BDCA4+_DentriticCells | 6.2 | |
| Bonemarrow | 6.3 | |
| BronchialEpithelialCells | 6 | |
| CD105+_Endothelial | 5.75 | |
| CD14+_Monocytes | 6.55 | |
| CD19+_BCells(neg._sel.) | 6.1 | |
| CD33+_Myeloid | 7.65 | |
| CD34+ | 7.25 | |
| CD4+_Tcells | 6.3 | |
| CD56+_NKCells | 7.15 | |
| CD71+_EarlyErythroid | 5.6 | |
| CD8+_Tcells | 5.25 | |
| CardiacMyocytes | 10.65 | |
| Caudatenucleus | 5.55 | |
| Cerebellum | 5.05 | |
| CerebellumPeduncles | 9.65 | |
| CiliaryGanglion | 5.7 | |
| CingulateCortex | 6.4 | |
| Colorectaladenocarcinoma | 6.3 | |
| DorsalRootGanglion | 5.1 | |
| FetalThyroid | 6.15 | |
| Fetalbrain | 6.05 | |
| Fetalliver | 5.45 | |
| Fetallung | 5.1 | |
| GlobusPallidus | 4.75 | |
| Heart | 10.05 | |
| Hypothalamus | 6.6 | |
| Kidney | 5.5 | |
| Leukemia_chronicMyelogenousK-562 | 5.6 | |
| Leukemia_promyelocytic-HL-60 | 5.05 | |
| Leukemialymphoblastic(MOLT-4) | 4.7 | |
| Liver | 8.5 | |
| Lung | 11.95 | |
| Lymphnode | 5.35 | |
| Lymphoma_burkitts(Daudi) | 7.8 | |
| Lymphoma_burkitts(Raji) | 8.85 | |
| MedullaOblongata | 5.45 | |
| OccipitalLobe | 5.5 | |
| OlfactoryBulb | 4.9 | |
| Ovary | 4.25 | |
| Pancreas | 4.9 | |
| PancreaticIslet | 6.65 | |
| ParietalLobe | 6.75 | |
| Pituitary | 7.3 | |
| Placenta | 6.3 | |
| Pons | 5.9 | |
| PrefrontalCortex | 7.2 | |
| Prostate | 7.15 | |
| Salivarygland | 5 | |
| SkeletalMuscle | 9 | |
| Skin | 8.85 | |
| SmoothMuscle | 7.05 | |
| Spinalcord | 6.6 | |
| SubthalamicNucleus | 5.6 | |
| SuperiorCervicalGanglion | 7.55 | |
| TemporalLobe | 5.7 | |
| Testis | 9.2 | |
| TestisGermCell | 18.3 | |
| TestisIntersitial | 13.85 | |
| TestisLeydigCell | 7.8 | |
| TestisSeminiferousTubule | 7.8 | |
| Thalamus | 6.35 | |
| Thymus | 4.65 | |
| Thyroid | 12.75 | |
| Tongue | 6.4 | |
| Tonsil | 6 | |
| Trachea | 5.2 | |
| TrigeminalGanglion | 6.65 | |
| Uterus | 4.85 | |
| UterusCorpus | 6.1 | |
| WholeBlood | 6.4 | |
| Wholebrain | 4.95 | |
| colon | 6.05 | |
| pineal_day | 7.78 | |
| pineal_night | 7.54 | |
| retina | 7.475 | |
| small_intestine | 5.95 | |
- Probe name: CUST_55_PI416408490
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 2.96 ± 1.01 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 2.61 ± 0.63 | |
| Basal Part of Pons | 2.56 ± 1.06 | |
| Cerebellar Cortex | 2.01 ± 0.38 | |
| Cerebellar Nuclei | 2.89 ± 0.56 | |
| Claustrum | 3.13 ± 0.95 | |
| Epithalamus | 2.19 ± 1.07 | |
| Frontal Lobe | 2.48 ± 0.81 | |
| Globus Pallidus | 2.53 ± 0.52 | |
| Hypothalamus | 2.73 ± 0.78 | |
| Insula | 2.09 ± 0.72 | |
| Limbic Lobe | 2.72 ± 0.97 | |
| Mesencephalon | 2.89 ± 1.05 | |
| Myelencephalon | 2.73 ± 0.85 | |
| Occipital Lobe | 2.64 ± 1.08 | |
| Parietal Lobe | 2.9 ± 0.77 | |
| Pontine Tegmentum | 2.77 ± 0.88 | |
| Striatum | 5.02 ± 0.64 | |
| Subthalamus | 2.84 ± 0.36 | |
| Temporal Lobe | 2.55 ± 0.83 | |
| Thalamus | 2.62 ± 0.84 | |
| White Matter | 1.91 ± 0.16 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Ace | CB | Cerebellum | 7.05 | |
| 11.72 | | |||
| Ace | CTX | Cerebral cortex | 3.51 | |
| 4 | | |||
| Ace | HIP | Hippocampal region | 4.85 | |
| 6.25 | | |||
| Ace | HPF | Hippocampal formation | 5.26 | |
| 5.64 | | |||
| Ace | HY | Hypothalamus | 4.57 | |
| 4.68 | | |||
| Ace | LSX | Lateral septal complex | 2.7 | |
| 6.09 | | |||
| Ace | MB | Midbrain | 3.59 | |
| 4.32 | | |||
| Ace | MY | Medulla | 15.54 | |
| 24.77 | | |||
| Ace | OLF | Olfactory bulb | 2.36 | |
| 2.16 | | |||
| Ace | P | Pons | 6.92 | |
| 10.53 | | |||
| Ace | PAL | Pallidum | 3.41 | |
| 3.55 | | |||
| Ace | RHP | Retrohippocampal region | 6 | |
| 4.76 | | |||
| Ace | sAMY | Striatum-like amygdalar nuclei | 1.92 | |
| 1.85 | | |||
| Ace | STR | Striatum | 19.69 | |
| 15.35 | | |||
| Ace | STRd | Striatum dorsal region | 30.57 | |
| 23.73 | | |||
| Ace | STRv | Striatum ventral region | 1.41 | |
| 1.12 | | |||
| Ace | TH | Thalamus | 4.91 | |
| 6.01 | |
| Peptide Name | Peptide Lengh | Peptide Start | Peptide End | Peptide Sequence | Source |
|---|---|---|---|---|---|
| ACE_HUMAN_0 | 0 | 0 | 0 | IAFLPFGYLVDQWR | PRIDE |
| ACE_HUMAN_461 | 14 | 461 | 474 | IAFLPFGYLVDQWR | PRIDE |
| PAp00381843 | 10 | 523 | 532 | YQGLCPPVPR | Peptide Atlas |