AutismKB 2.0

Annotation Detail for AP1G1


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Basic Information Top
Gene Symbol:AP1G1 ( ADTG,CLAPG1,MGC18255 )
Gene Full Name: adaptor-related protein complex 1, gamma 1 subunit
Band: 16q22.2
Quick LinksEntrez ID:164; OMIM: 603533; Uniprot ID:AP1G1_HUMAN; ENSEMBL ID: ENSG00000166747; HGNC ID: 555
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body4 / 7076156
blastocyst6 / 6231996
fetus62 / 564012109
neonate1 / 3109732
infant0 / 236200 
juvenile1 / 5555617
adult169 / 193912187
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma2 / 17475114
breast (mammary gland) tumor16 / 94178169
cervical tumor0 / 343660 
chondrosarcoma4 / 8282348
colorectal tumor15 / 114246131
esophageal tumor0 / 172900 
gastrointestinal tumor11 / 11936992
germ cell tumor40 / 263845151
glioma8 / 10688374
head and neck tumor14 / 136302102
kidney tumor2 / 6895929
leukemia8 / 9584283
liver tumor3 / 9635931
lung tumor1 / 1031279
lymphoma0 / 717550 
non-neoplasia7 / 9725071
normal312 / 336030792
ovarian tumor6 / 7668278
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer6 / 10268058
retinoblastoma0 / 463560 
skin tumor6 / 12494948
soft tissue/muscle tissue tumor8 / 12519163
uterine tumor6 / 9025766
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland0 / 331970 
ascites3 / 4001574
bladder2 / 2975767
blood10 / 12347880
bone4 / 7165555
bone marrow1 / 4880120
brain154 / 1100989139
cervix0 / 481710 
connective tissue6 / 14925540
ear2 / 16212123
embryonic tissue13 / 21572260
esophagus0 / 202090 
eye16 / 21105475
heart3 / 8962633
intestine20 / 23447285
kidney9 / 21177742
larynx0 / 241450 
liver9 / 20774343
lung20 / 33697459
lymph0 / 442700 
lymph node14 / 91610152
mammary gland23 / 153271150
mouth7 / 67052104
muscle5 / 10771546
nerve1 / 1576863
ovary6 / 10205158
pancreas6 / 21481227
parathyroid0 / 205390 
pharynx6 / 41328145
pituitary gland0 / 165850 
placenta26 / 28082592
prostate8 / 18934542
salivary gland0 / 201550 
skin10 / 21057447
spleen1 / 5395218
stomach8 / 9661982
testis93 / 330442281
thymus5 / 8113161
thyroid2 / 4747342
tonsil0 / 169990 
trachea24 / 52413457
umbilical cord1 / 1368073
uterus25 / 232878107
vascular4 / 5178077
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 203350_at
Cell line Expression level Expression bar
721_B_lymphoblasts15.3
Adipocyte6.8
AdrenalCortex7.2
Adrenalgland5.75
Amygdala7.3
Appendix7.5
AtrioventricularNode5.3
BDCA4+_DentriticCells7.75
Bonemarrow6.75
BronchialEpithelialCells6.95
CD105+_Endothelial6.7
CD14+_Monocytes7.3
CD19+_BCells(neg._sel.)7.5
CD33+_Myeloid8.85
CD34+8.8
CD4+_Tcells7.8
CD56+_NKCells9.9
CD71+_EarlyErythroid6.25
CD8+_Tcells9.05
CardiacMyocytes8.7
Caudatenucleus6.1
Cerebellum5.4
CerebellumPeduncles7.75
CiliaryGanglion5.2
CingulateCortex6.85
Colorectaladenocarcinoma6.65
DorsalRootGanglion6
FetalThyroid6.75
Fetalbrain8.55
Fetalliver5.8
Fetallung5.9
GlobusPallidus4.9
Heart8.55
Hypothalamus7.7
Kidney5.5
Leukemia_chronicMyelogenousK-5626.2
Leukemia_promyelocytic-HL-605.95
Leukemialymphoblastic(MOLT-4)5.6
Liver8.9
Lung7.5
Lymphnode5.75
Lymphoma_burkitts(Daudi)9.1
Lymphoma_burkitts(Raji)9.45
MedullaOblongata6.3
OccipitalLobe6.15
OlfactoryBulb6
Ovary5
Pancreas5.4
PancreaticIslet7.5
ParietalLobe7.25
Pituitary7.9
Placenta16.65
Pons6.45
PrefrontalCortex9.05
Prostate8.1
Salivarygland5.6
SkeletalMuscle7.95
Skin6.05
SmoothMuscle8.3
Spinalcord7.2
SubthalamicNucleus7.3
SuperiorCervicalGanglion9.25
TemporalLobe6.35
Testis32.35
TestisGermCell56.7
TestisIntersitial26.2
TestisLeydigCell14.2
TestisSeminiferousTubule24.7
Thalamus7.05
Thymus5.55
Thyroid8.85
Tongue6.65
Tonsil8.55
Trachea5.75
TrigeminalGanglion6.75
Uterus5.65
UterusCorpus6.05
WholeBlood13.85
Wholebrain6.55
colon6.85
pineal_day9.48
pineal_night12.44
retina8.45
small_intestine6.45
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P318208
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.42 ± 0.35
Basal Forebrain7.2 ± 0.2
Basal Part of Pons7.49 ± 0.26
Cerebellar Cortex7.35 ± 0.33
Cerebellar Nuclei7.62 ± 0.28
Claustrum7.77 ± 0.44
Epithalamus7.2 ± 0.24
Frontal Lobe7.35 ± 0.38
Globus Pallidus7.33 ± 0.33
Hypothalamus7.3 ± 0.26
Insula7.37 ± 0.14
Limbic Lobe7.51 ± 0.33
Mesencephalon7.39 ± 0.4
Myelencephalon7.38 ± 0.36
Occipital Lobe7.59 ± 0.24
Parietal Lobe7.44 ± 0.27
Pontine Tegmentum7.43 ± 0.29
Striatum7.36 ± 0.21
Subthalamus7.48 ± 0.26
Temporal Lobe7.33 ± 0.32
Thalamus7.43 ± 0.24
White Matter7.88 ± 0.17
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Ap1g1CBCerebellum28.84
46.07
Ap1g1CTXCerebral cortex86.35
72.9
Ap1g1HIPHippocampal region47.02
76.3
Ap1g1HPFHippocampal formation59.71
73.88
Ap1g1HYHypothalamus50.08
40.68
Ap1g1LSXLateral septal complex34.54
24.64
Ap1g1MBMidbrain41.36
40.21
Ap1g1MYMedulla50.86
61.11
Ap1g1OLFOlfactory bulb76
67.94
Ap1g1PPons45.52
52.57
Ap1g1PALPallidum50.82
48.83
Ap1g1RHPRetrohippocampal region83.33
74.02
Ap1g1sAMYStriatum-like amygdalar nuclei71.05
58.15
Ap1g1STRStriatum51.91
40.05
Ap1g1STRdStriatum dorsal region48.57
37.9
Ap1g1STRvStriatum ventral region64.16
46.48
Ap1g1THThalamus48.44
46.41
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
AP1G1_HUMAN_204 9 204 212 SPDMLAHFR PRIDE
AP1G1_HUMAN_282 18 282 299 NVGNAILYETVLTIMDIK PRIDE
PAp00007911 17 19 35 TQAEEREMIQKECAAIR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018