AutismKB 2.0

Annotation Detail for DDIT3


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:DDIT3 ( CEBPZ,CHOP,CHOP-10,CHOP10,GADD153,MGC4154 )
Gene Full Name: DNA-damage-inducible transcript 3
Band: 12q13.3
Quick LinksEntrez ID:1649; OMIM: 126337; Uniprot ID:DDIT3_HUMAN; ENSEMBL ID: ENSG00000175197; HGNC ID: 2726
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst1 / 6231916
fetus4 / 5640127
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult108 / 193912155
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor2 / 12794156
bladder carcinoma1 / 1747557
breast (mammary gland) tumor1 / 9417810
cervical tumor2 / 3436658
chondrosarcoma7 / 8282384
colorectal tumor17 / 114246148
esophageal tumor2 / 17290115
gastrointestinal tumor4 / 11936933
germ cell tumor4 / 26384515
glioma2 / 10688318
head and neck tumor2 / 13630214
kidney tumor4 / 6895958
leukemia4 / 9584241
liver tumor2 / 9635920
lung tumor4 / 10312738
lymphoma2 / 7175527
non-neoplasia1 / 9725010
normal172 / 336030751
ovarian tumor2 / 7668226
pancreatic tumor7 / 10461666
primitive neuroectodermal tumor of the CNS3 / 12568023
prostate cancer3 / 10268029
retinoblastoma0 / 463560 
skin tumor2 / 12494916
soft tissue/muscle tissue tumor22 / 125191175
uterine tumor3 / 9025733
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue2 / 13106152
adrenal gland2 / 3319760
ascites2 / 4001549
bladder0 / 297570 
blood12 / 12347897
bone7 / 7165597
bone marrow6 / 48801122
brain25 / 110098922
cervix2 / 4817141
connective tissue6 / 14925540
ear0 / 162120 
embryonic tissue3 / 21572213
esophagus2 / 2020998
eye31 / 211054146
heart1 / 8962611
intestine22 / 23447293
kidney9 / 21177742
larynx0 / 241450 
liver19 / 20774391
lung12 / 33697435
lymph2 / 4427045
lymph node6 / 9161065
mammary gland4 / 15327126
mouth0 / 670520 
muscle24 / 107715222
nerve0 / 157680 
ovary4 / 10205139
pancreas9 / 21481241
parathyroid2 / 2053997
pharynx1 / 4132824
pituitary gland2 / 16585120
placenta13 / 28082546
prostate6 / 18934531
salivary gland0 / 201550 
skin4 / 21057418
spleen0 / 539520 
stomach25 / 96619258
testis7 / 33044221
thymus5 / 8113161
thyroid3 / 4747363
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus6 / 23287825
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 209383_at
Cell line Expression level Expression bar
721_B_lymphoblasts99.7
Adipocyte89.6
AdrenalCortex96.15
Adrenalgland91.9
Amygdala89.6
Appendix101.5
AtrioventricularNode73.9
BDCA4+_DentriticCells57.65
Bonemarrow92.6
BronchialEpithelialCells85.25
CD105+_Endothelial55.1
CD14+_Monocytes45.5
CD19+_BCells(neg._sel.)89.45
CD33+_Myeloid97.6
CD34+67.8
CD4+_Tcells69.65
CD56+_NKCells101.15
CD71+_EarlyErythroid40.55
CD8+_Tcells80.75
CardiacMyocytes64.3
Caudatenucleus123.3
Cerebellum75.2
CerebellumPeduncles107.6
CiliaryGanglion63.5
CingulateCortex89.75
Colorectaladenocarcinoma87.6
DorsalRootGanglion72.05
FetalThyroid99.55
Fetalbrain82
Fetalliver78.4
Fetallung75
GlobusPallidus65.45
Heart107.7
Hypothalamus114.2
Kidney97.55
Leukemia_chronicMyelogenousK-562220.9
Leukemia_promyelocytic-HL-60111.35
Leukemialymphoblastic(MOLT-4)69.2
Liver110.4
Lung75.25
Lymphnode78.7
Lymphoma_burkitts(Daudi)228.05
Lymphoma_burkitts(Raji)143.1
MedullaOblongata88.1
OccipitalLobe77.3
OlfactoryBulb100.1
Ovary57.2
Pancreas78.85
PancreaticIslet155.95
ParietalLobe106.55
Pituitary111.8
Placenta87.15
Pons87.8
PrefrontalCortex88.65
Prostate47.05
Salivarygland75.4
SkeletalMuscle111.25
Skin68.5
SmoothMuscle77.55
Spinalcord125.35
SubthalamicNucleus77.9
SuperiorCervicalGanglion136.35
TemporalLobe93.9
Testis83.8
TestisGermCell74.45
TestisIntersitial70
TestisLeydigCell85.2
TestisSeminiferousTubule96.25
Thalamus108.15
Thymus64.45
Thyroid107
Tongue82.5
Tonsil84.65
Trachea75.85
TrigeminalGanglion93.6
Uterus46.2
UterusCorpus88.4
WholeBlood97.05
Wholebrain73.75
colon21.75
pineal_day333.64
pineal_night162.86
retina140.25
small_intestine17.2
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P21134
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.86 ± 0.29
Basal Forebrain6.28 ± 0.2
Basal Part of Pons6.35 ± 0.33
Cerebellar Cortex6.32 ± 0.26
Cerebellar Nuclei6.58 ± 0.32
Claustrum5.95 ± 0.29
Epithalamus6.92 ± 0.26
Frontal Lobe6.31 ± 0.27
Globus Pallidus6.62 ± 0.13
Hypothalamus6.4 ± 0.57
Insula6.21 ± 0.23
Limbic Lobe6.1 ± 0.27
Mesencephalon6.27 ± 0.28
Myelencephalon6.23 ± 0.32
Occipital Lobe5.95 ± 0.3
Parietal Lobe6.19 ± 0.3
Pontine Tegmentum6.26 ± 0.31
Striatum6.45 ± 0.39
Subthalamus6.41 ± 0.03
Temporal Lobe6.14 ± 0.29
Thalamus6.28 ± 0.27
White Matter7.03 ± 0.1
Mouse Brain ISH
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved