AutismKB 2.0

Annotation Detail for FAM171B


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Basic Information Top
Gene Symbol:FAM171B ( FLJ34104,KIAA1946 )
Gene Full Name: family with sequence similarity 171, member B
Band: 2q32.1
Quick LinksEntrez ID:165215; OMIM: NA; Uniprot ID:F171B_HUMAN; ENSEMBL ID: ENSG00000144369; HGNC ID: 29412
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus22 / 56401239
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult39 / 193912120
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor2 / 11936916
germ cell tumor0 / 2638450 
glioma2 / 10688318
head and neck tumor0 / 1363020 
kidney tumor1 / 6895914
leukemia1 / 9584210
liver tumor0 / 963590 
lung tumor2 / 10312719
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal87 / 336030725
ovarian tumor0 / 766820 
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder2 / 2975767
blood0 / 1234780 
bone0 / 716550 
bone marrow1 / 4880120
brain44 / 110098939
cervix0 / 481710 
connective tissue0 / 1492550 
ear3 / 16212185
embryonic tissue4 / 21572218
esophagus0 / 202090 
eye4 / 21105418
heart0 / 896260 
intestine4 / 23447217
kidney1 / 2117774
larynx0 / 241450 
liver0 / 2077430 
lung13 / 33697438
lymph0 / 442700 
lymph node0 / 916100 
mammary gland5 / 15327132
mouth0 / 670520 
muscle1 / 1077159
nerve1 / 1576863
ovary0 / 1020510 
pancreas1 / 2148124
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland2 / 16585120
placenta17 / 28082560
prostate1 / 1893455
salivary gland0 / 201550 
skin1 / 2105744
spleen0 / 539520 
stomach0 / 966190 
testis0 / 3304420 
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus2 / 2328788
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_32_P202759
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala8.6 ± 0.3
Basal Forebrain8.31 ± 0.37
Basal Part of Pons7.48 ± 0.23
Cerebellar Cortex7.74 ± 0.19
Cerebellar Nuclei7.05 ± 0.4
Claustrum8.49 ± 0.43
Epithalamus8.17 ± 0.39
Frontal Lobe8.31 ± 0.42
Globus Pallidus7.19 ± 0.61
Hypothalamus8.17 ± 0.26
Insula8.47 ± 0.18
Limbic Lobe8.39 ± 0.58
Mesencephalon7.88 ± 0.49
Myelencephalon8.12 ± 0.6
Occipital Lobe7.59 ± 0.57
Parietal Lobe8.01 ± 0.46
Pontine Tegmentum8.26 ± 0.51
Striatum8.39 ± 0.5
Subthalamus7.54 ± 0.16
Temporal Lobe8.4 ± 0.43
Thalamus7.88 ± 0.5
White Matter6.49 ± 0.66
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
D430039N05RikCBCerebellum25.82
29.16
D430039N05RikCTXCerebral cortex100
100
D430039N05RikHIPHippocampal region100
100
D430039N05RikHPFHippocampal formation100
100
D430039N05RikHYHypothalamus65.39
64.4
D430039N05RikLSXLateral septal complex55.82
51.32
D430039N05RikMBMidbrain70.71
71.71
D430039N05RikMYMedulla54.92
65.13
D430039N05RikOLFOlfactory bulb100
100
D430039N05RikPPons55.43
63.77
D430039N05RikPALPallidum30.03
30.62
D430039N05RikRHPRetrohippocampal region100
100
D430039N05RiksAMYStriatum-like amygdalar nuclei67.69
68.01
D430039N05RikSTRStriatum69.18
61.54
D430039N05RikSTRdStriatum dorsal region74.27
66.39
D430039N05RikSTRvStriatum ventral region61.03
47.39
D430039N05RikTHThalamus68.62
71.55
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018