AutismKB 2.0

Annotation Detail for DDX3X


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:DDX3X ( DBX,DDX14,DDX3,HLP2 )
Gene Full Name: DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked
Band: Xp11.4
Quick LinksEntrez ID:1654; OMIM: 300160; Uniprot ID:DDX3X_HUMAN; ENSEMBL ID: ENSG00000215301; HGNC ID: 2745
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus3 / 5640125
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult7 / 19391213
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor1 / 2638453
glioma1 / 1068839
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal13 / 33603073
ovarian tumor1 / 7668213
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer2 / 10268019
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow1 / 4880120
brain5 / 11009894
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye1 / 2110544
heart0 / 896260 
intestine1 / 2344724
kidney0 / 2117770 
larynx0 / 241450 
liver1 / 2077434
lung2 / 3369745
lymph0 / 442700 
lymph node0 / 916100 
mammary gland1 / 1532716
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary1 / 1020519
pancreas0 / 2148120 
parathyroid1 / 2053948
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta1 / 2808253
prostate2 / 18934510
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach0 / 966190 
testis1 / 3304423
thymus1 / 8113112
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 201211_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts37.95
Adipocyte7.4
AdrenalCortex6.25
Adrenalgland5.6
Amygdala7
Appendix5.8
AtrioventricularNode4.6
BDCA4+_DentriticCells80.55
Bonemarrow6.85
BronchialEpithelialCells7.5
CD105+_Endothelial10.85
CD14+_Monocytes7.45
CD19+_BCells(neg._sel.)9.9
CD33+_Myeloid234.95
CD34+14.9
CD4+_Tcells30.25
CD56+_NKCells14.45
CD71+_EarlyErythroid25.65
CD8+_Tcells80.6
CardiacMyocytes11.4
Caudatenucleus5.7
Cerebellum5.4
CerebellumPeduncles7.55
CiliaryGanglion4.3
CingulateCortex6.1
Colorectaladenocarcinoma7.85
DorsalRootGanglion5
FetalThyroid6.45
Fetalbrain6.65
Fetalliver8.65
Fetallung5.85
GlobusPallidus4.25
Heart8.4
Hypothalamus6.4
Kidney5.25
Leukemia_chronicMyelogenousK-5626
Leukemia_promyelocytic-HL-606
Leukemialymphoblastic(MOLT-4)6
Liver7.75
Lung6.4
Lymphnode5.85
Lymphoma_burkitts(Daudi)7.4
Lymphoma_burkitts(Raji)9.3
MedullaOblongata6.05
OccipitalLobe5.95
OlfactoryBulb5.25
Ovary4.6
Pancreas5.4
PancreaticIslet7.4
ParietalLobe7.05
Pituitary9.55
Placenta8.45
Pons6.3
PrefrontalCortex8.3
Prostate7.75
Salivarygland5.3
SkeletalMuscle7.4
Skin4.55
SmoothMuscle9.2
Spinalcord6.35
SubthalamicNucleus6.05
SuperiorCervicalGanglion6.55
TemporalLobe6.1
Testis5.75
TestisGermCell29.55
TestisIntersitial18.2
TestisLeydigCell11.65
TestisSeminiferousTubule12.55
Thalamus5.85
Thymus5.3
Thyroid8.45
Tongue6.45
Tonsil9.75
Trachea5.6
TrigeminalGanglion6.6
Uterus5.6
UterusCorpus5.9
WholeBlood18.25
Wholebrain5.45
colon12.9
pineal_day8.36
pineal_night8.2
retina8.05
small_intestine7.2
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P317654
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.3 ± 0.25
Basal Forebrain7.53 ± 0.18
Basal Part of Pons7.4 ± 0.2
Cerebellar Cortex7.24 ± 0.2
Cerebellar Nuclei7.64 ± 0.24
Claustrum7.34 ± 0.37
Epithalamus7.72 ± 0.14
Frontal Lobe7.33 ± 0.27
Globus Pallidus7.91 ± 0.23
Hypothalamus7.51 ± 0.38
Insula7.19 ± 0.19
Limbic Lobe7.34 ± 0.26
Mesencephalon7.51 ± 0.17
Myelencephalon7.4 ± 0.26
Occipital Lobe7.71 ± 0.25
Parietal Lobe7.44 ± 0.22
Pontine Tegmentum7.39 ± 0.32
Striatum7.49 ± 0.34
Subthalamus7.4 ± 0.2
Temporal Lobe7.31 ± 0.26
Thalamus7.49 ± 0.22
White Matter7.94 ± 0.2
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Ddx3xCBCerebellum2.3
2.87
Ddx3xCTXCerebral cortex0.28
0.34
Ddx3xHIPHippocampal region4.01
2.14
Ddx3xHPFHippocampal formation3.58
2.51
Ddx3xHYHypothalamus0.4
0.42
Ddx3xLSXLateral septal complex0.26
0.14
Ddx3xMBMidbrain0.43
0.4
Ddx3xMYMedulla4.28
4.24
Ddx3xOLFOlfactory bulb1.11
1.36
Ddx3xPPons1.86
1.71
Ddx3xPALPallidum0.2
0.15
Ddx3xRHPRetrohippocampal region2.89
3.65
Ddx3xsAMYStriatum-like amygdalar nuclei0.25
0.3
Ddx3xSTRStriatum0.2
0.19
Ddx3xSTRdStriatum dorsal region0.17
0.19
Ddx3xSTRvStriatum ventral region0.28
0.16
Ddx3xTHThalamus0.39
0.23
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
DDX3X_HUMAN_230 22 230 251 TAAFLLPILSQIYSDGPGEALR PRIDE
DDX3X_HUMAN_351 11 351 361 MLDMGFEPQIR PRIDE
DDX3X_HUMAN_376 11 376 386 HTMMFSATFPK PRIDE
DDX3X_HUMAN_488 15 488 502 SGKSPILVATAVAAR PRIDE
DDX3X_HUMAN_489 15 489 503 SGKSPILVATAVAAR PRIDE
DDX3X_HUMAN_534 14 534 547 VGNLGLATSFFNER PRIDE
DDX3X_HUMAN_554 10 554 563 DLLDLLVEAK PRIDE
DDX3X_HUMAN_603 14 603 616 QSSGASSSSFSSSR PRIDE
PAp00001717 12 219 230 DLMACAQTGSGK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved