AutismKB 2.0

Annotation Detail for PRICKLE2


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Basic Information Top
Gene Symbol:PRICKLE2 ( DKFZp686D143,DKFZp686H1748,DKFZp686M031 )
Gene Full Name: prickle homolog 2 (Drosophila)
Band: 3p14.1
Quick LinksEntrez ID:166336; OMIM: 608501; Uniprot ID:PRIC2_HUMAN; ENSEMBL ID: ENSG00000163637; HGNC ID: 20340
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_7405_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.57 ± 0.7
Basal Forebrain3.99 ± 0.43
Basal Part of Pons4.52 ± 0.47
Cerebellar Cortex3.83 ± 0.51
Cerebellar Nuclei3.57 ± 0.45
Claustrum4.54 ± 0.89
Epithalamus4.21 ± 0.49
Frontal Lobe4.55 ± 0.56
Globus Pallidus4 ± 0.8
Hypothalamus3.97 ± 0.55
Insula4.67 ± 0.5
Limbic Lobe5.08 ± 0.62
Mesencephalon4.48 ± 0.57
Myelencephalon4.45 ± 0.62
Occipital Lobe4.8 ± 0.55
Parietal Lobe4.57 ± 0.47
Pontine Tegmentum4.31 ± 0.6
Striatum4.38 ± 0.77
Subthalamus3.98 ± 0.44
Temporal Lobe4.64 ± 0.47
Thalamus4.38 ± 0.48
White Matter3.11 ± 0.42
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Prickle2CBCerebellum69.51
100
Prickle2CTXCerebral cortex100
100
Prickle2HIPHippocampal region100
100
Prickle2HPFHippocampal formation100
100
Prickle2HYHypothalamus100
100
Prickle2LSXLateral septal complex100
100
Prickle2MBMidbrain100
100
Prickle2MYMedulla100
100
Prickle2OLFOlfactory bulb100
100
Prickle2PPons100
100
Prickle2PALPallidum100
100
Prickle2RHPRetrohippocampal region100
100
Prickle2sAMYStriatum-like amygdalar nuclei100
100
Prickle2STRStriatum100
100
Prickle2STRdStriatum dorsal region100
100
Prickle2STRvStriatum ventral region100
100
Prickle2THThalamus100
100
Peptide Top

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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018