AutismKB 2.0

Annotation Detail for SPATA5


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Basic Information Top
Gene Symbol:SPATA5 ( AFG2,SPAF )
Gene Full Name: spermatogenesis associated 5
Band: 4q28.1
Quick LinksEntrez ID:166378; OMIM: NA; Uniprot ID:SPAT5_HUMAN; ENSEMBL ID: ENSG00000145375; HGNC ID: 18119
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus14 / 56401224
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult16 / 19391218
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor2 / 9417821
cervical tumor0 / 343660 
chondrosarcoma6 / 8282372
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor7 / 26384526
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor2 / 6895929
leukemia2 / 9584220
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal38 / 336030711
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor3 / 12494924
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland1 / 3319730
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone6 / 7165583
bone marrow1 / 4880120
brain7 / 11009896
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue1 / 2157224
esophagus0 / 202090 
eye3 / 21105414
heart1 / 8962611
intestine0 / 2344720 
kidney4 / 21177718
larynx0 / 241450 
liver2 / 2077439
lung1 / 3369742
lymph0 / 442700 
lymph node2 / 9161021
mammary gland5 / 15327132
mouth0 / 670520 
muscle1 / 1077159
nerve1 / 1576863
ovary1 / 1020519
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta1 / 2808253
prostate0 / 1893450 
salivary gland0 / 201550 
skin4 / 21057418
spleen0 / 539520 
stomach0 / 966190 
testis2 / 3304426
thymus2 / 8113124
thyroid0 / 474730 
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus2 / 2328788
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_1429_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.73 ± 0.97
Basal Forebrain3.66 ± 0.41
Basal Part of Pons3.45 ± 0.58
Cerebellar Cortex3.95 ± 0.45
Cerebellar Nuclei3.8 ± 0.91
Claustrum3.46 ± 0.55
Epithalamus4 ± 0.46
Frontal Lobe3.43 ± 0.66
Globus Pallidus4.26 ± 0.66
Hypothalamus3.41 ± 0.49
Insula3.32 ± 0.63
Limbic Lobe3.49 ± 0.59
Mesencephalon3.77 ± 0.65
Myelencephalon3.58 ± 0.54
Occipital Lobe3.82 ± 0.56
Parietal Lobe3.55 ± 0.64
Pontine Tegmentum3.72 ± 0.75
Striatum3.56 ± 0.7
Subthalamus3.93 ± 0.51
Temporal Lobe3.54 ± 0.64
Thalamus3.67 ± 0.53
White Matter4.72 ± 0.11
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Spata5CBCerebellum14.84
16.62
Spata5CTXCerebral cortex58.01
41.87
Spata5HIPHippocampal region36.18
41.47
Spata5HPFHippocampal formation37.47
37.98
Spata5HYHypothalamus12.26
9.34
Spata5LSXLateral septal complex19.78
13.59
Spata5MBMidbrain17.97
15.61
Spata5MYMedulla23.88
26.5
Spata5OLFOlfactory bulb53.24
45.57
Spata5PPons20.59
21.01
Spata5PALPallidum16.83
13.81
Spata5RHPRetrohippocampal region39.5
33.6
Spata5sAMYStriatum-like amygdalar nuclei13.04
9.28
Spata5STRStriatum24.52
16.86
Spata5STRdStriatum dorsal region24.03
16.47
Spata5STRvStriatum ventral region34.39
22.88
Spata5THThalamus22.03
17.84
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00010809 22 10 31 LNQSAENGSSLPSAASSCAEAR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018