AutismKB 2.0

Annotation Detail for DHX15


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Basic Information Top
Gene Symbol:DHX15 ( DBP1,DDX15,HRH2,PRP43,PRPF43,PrPp43p )
Gene Full Name: DEAH (Asp-Glu-Ala-His) box polypeptide 15
Band: 4p15.2
Quick LinksEntrez ID:1665; OMIM: 603403; Uniprot ID:DHX15_HUMAN; ENSEMBL ID: ENSG00000109606; HGNC ID: 2738
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body8 / 70761113
blastocyst17 / 62319272
fetus111 / 564012196
neonate6 / 31097192
infant1 / 2362042
juvenile11 / 55556197
adult214 / 1939121110
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma2 / 17475114
breast (mammary gland) tumor14 / 94178148
cervical tumor2 / 3436658
chondrosarcoma12 / 82823144
colorectal tumor12 / 114246105
esophageal tumor3 / 17290173
gastrointestinal tumor12 / 119369100
germ cell tumor64 / 263845242
glioma1 / 1068839
head and neck tumor23 / 136302168
kidney tumor5 / 6895972
leukemia2 / 9584220
liver tumor15 / 96359155
lung tumor12 / 103127116
lymphoma5 / 7175569
non-neoplasia9 / 9725092
normal388 / 3360307115
ovarian tumor6 / 7668278
pancreatic tumor4 / 10461638
primitive neuroectodermal tumor of the CNS7 / 12568055
prostate cancer5 / 10268048
retinoblastoma14 / 46356302
skin tumor13 / 124949104
soft tissue/muscle tissue tumor10 / 12519179
uterine tumor8 / 9025788
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland5 / 33197150
ascites2 / 4001549
bladder5 / 29757168
blood14 / 123478113
bone10 / 71655139
bone marrow2 / 4880140
brain119 / 1100989108
cervix2 / 4817141
connective tissue22 / 149255147
ear10 / 16212616
embryonic tissue34 / 215722157
esophagus3 / 20209148
eye26 / 211054123
heart14 / 89626156
intestine29 / 234472123
kidney38 / 211777179
larynx0 / 241450 
liver18 / 20774386
lung45 / 336974133
lymph1 / 4427022
lymph node9 / 9161098
mammary gland24 / 153271156
mouth21 / 67052313
muscle10 / 10771592
nerve3 / 15768190
ovary7 / 10205168
pancreas13 / 21481260
parathyroid2 / 2053997
pharynx4 / 4132896
pituitary gland2 / 16585120
placenta20 / 28082571
prostate10 / 18934552
salivary gland1 / 2015549
skin19 / 21057490
spleen5 / 5395292
stomach9 / 9661993
testis55 / 330442166
thymus51 / 81131628
thyroid1 / 4747321
tonsil3 / 16999176
trachea6 / 52413114
umbilical cord2 / 13680146
uterus25 / 232878107
vascular6 / 51780115
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 201386_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts1040.65
Adipocyte74.7
AdrenalCortex42.95
Adrenalgland25.95
Amygdala71.1
Appendix53.45
AtrioventricularNode23.45
BDCA4+_DentriticCells437.45
Bonemarrow42.5
BronchialEpithelialCells363.5
CD105+_Endothelial303.3
CD14+_Monocytes178.35
CD19+_BCells(neg._sel.)201
CD33+_Myeloid333.05
CD34+578.2
CD4+_Tcells699.2
CD56+_NKCells273.1
CD71+_EarlyErythroid332.1
CD8+_Tcells556.45
CardiacMyocytes178.25
Caudatenucleus46
Cerebellum29.8
CerebellumPeduncles55.65
CiliaryGanglion28.45
CingulateCortex38.2
Colorectaladenocarcinoma64
DorsalRootGanglion48.45
FetalThyroid89.85
Fetalbrain146.15
Fetalliver72.85
Fetallung224.15
GlobusPallidus39.2
Heart33.45
Hypothalamus83.35
Kidney30.5
Leukemia_chronicMyelogenousK-562130.4
Leukemia_promyelocytic-HL-60341.3
Leukemialymphoblastic(MOLT-4)556.6
Liver36.55
Lung31.2
Lymphnode116.3
Lymphoma_burkitts(Daudi)504.3
Lymphoma_burkitts(Raji)146.2
MedullaOblongata38.6
OccipitalLobe74.5
OlfactoryBulb42.1
Ovary41.1
Pancreas45.75
PancreaticIslet105.1
ParietalLobe56.45
Pituitary100.35
Placenta94.65
Pons35.3
PrefrontalCortex51
Prostate41
Salivarygland91.85
SkeletalMuscle41.35
Skin52.05
SmoothMuscle272.3
Spinalcord70.7
SubthalamicNucleus34.65
SuperiorCervicalGanglion30.9
TemporalLobe34.9
Testis31.4
TestisGermCell104.9
TestisIntersitial109.95
TestisLeydigCell98.25
TestisSeminiferousTubule50.65
Thalamus65.5
Thymus62.35
Thyroid81.7
Tongue52.85
Tonsil165.4
Trachea48.05
TrigeminalGanglion33.9
Uterus73.35
UterusCorpus77.8
WholeBlood82.3
Wholebrain37.2
colon207.6
pineal_day222.56
pineal_night219.42
retina68.1
small_intestine72.8
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P69826
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.86 ± 0.28
Basal Forebrain8.03 ± 0.25
Basal Part of Pons8.09 ± 0.24
Cerebellar Cortex8.31 ± 0.15
Cerebellar Nuclei8.14 ± 0.16
Claustrum7.7 ± 0.36
Epithalamus8.2 ± 0.18
Frontal Lobe8 ± 0.28
Globus Pallidus7.93 ± 0.23
Hypothalamus8.13 ± 0.16
Insula7.93 ± 0.2
Limbic Lobe7.92 ± 0.36
Mesencephalon7.98 ± 0.3
Myelencephalon7.99 ± 0.31
Occipital Lobe8.04 ± 0.3
Parietal Lobe7.97 ± 0.3
Pontine Tegmentum7.97 ± 0.2
Striatum7.82 ± 0.27
Subthalamus7.95 ± 0.38
Temporal Lobe8.01 ± 0.28
Thalamus7.97 ± 0.26
White Matter8.72 ± 0.19
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Dhx15CBCerebellum11.33
12.08
Dhx15CTXCerebral cortex11.36
7.95
Dhx15HIPHippocampal region15.45
14.43
Dhx15HPFHippocampal formation13.52
11.51
Dhx15HYHypothalamus2.14
1.65
Dhx15LSXLateral septal complex2.27
1.54
Dhx15MBMidbrain4.27
3.92
Dhx15MYMedulla9.45
9.88
Dhx15OLFOlfactory bulb18.05
14.73
Dhx15PPons5.06
5.74
Dhx15PALPallidum3.07
2.68
Dhx15RHPRetrohippocampal region10.6
7.78
Dhx15sAMYStriatum-like amygdalar nuclei1.74
1.12
Dhx15STRStriatum4.53
3.07
Dhx15STRdStriatum dorsal region4.66
3.24
Dhx15STRvStriatum ventral region6.06
3.81
Dhx15THThalamus7.29
5.65
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
DHX15_HUMAN_235 9 235 243 YMTDGMLLR PRIDE
DHX15_HUMAN_244 10 244 253 EAMNDPLLER PRIDE
DHX15_HUMAN_253 12 253 264 YGVIILDEAHER PRIDE
DHX15_HUMAN_265 12 265 276 TLATDILMGVLK PRIDE
DHX15_HUMAN_516 23 516 538 KLGIDDLVHFDFMDPPAPETLMR PRIDE
DHX15_HUMAN_616 19 616 634 FAHIDGDHLTLLNVYHAFK PRIDE
DHX15_HUMAN_63 16 63 78 ASTNAMLISAGLPPLK PRIDE
DHX15_HUMAN_7 11 7 17 LDLGEDYPSGK PRIDE
PAp00010319 8 187 194 GVACTQPR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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