Annotation Detail for COCH
Basic Information Top
| Gene Symbol: | COCH ( COCH-5B2,COCH5B2,DFNA9 ) |
|---|---|
| Gene Full Name: | coagulation factor C homolog, cochlin (Limulus polyphemus) |
| Band: | 14q12 |
| Quick Links | Entrez ID:1690; OMIM: 603196; Uniprot ID:COCH_HUMAN; ENSEMBL ID: ENSG00000100473; HGNC ID: 2180 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.21016
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 1 / 70761 | 14 |  |
| blastocyst | 3 / 62319 | 48 | |
| fetus | 181 / 564012 | 320 |  |
| neonate | 0 / 31097 | 0 | |
| infant | 0 / 23620 | 0 | |
| juvenile | 10 / 55556 | 179 |  |
| adult | 34 / 1939121 | 17 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 0 / 17475 | 0 | |
| breast (mammary gland) tumor | 1 / 94178 | 10 |  |
| cervical tumor | 0 / 34366 | 0 | |
| chondrosarcoma | 2 / 82823 | 24 | |
| colorectal tumor | 2 / 114246 | 17 | |
| esophageal tumor | 0 / 17290 | 0 | |
| gastrointestinal tumor | 3 / 119369 | 25 | |
| germ cell tumor | 2 / 263845 | 7 | |
| glioma | 0 / 106883 | 0 | |
| head and neck tumor | 2 / 136302 | 14 | |
| kidney tumor | 2 / 68959 | 29 | |
| leukemia | 2 / 95842 | 20 | |
| liver tumor | 4 / 96359 | 41 | |
| lung tumor | 11 / 103127 | 106 | |
| lymphoma | 9 / 71755 | 125 | |
| non-neoplasia | 1 / 97250 | 10 | |
| normal | 279 / 3360307 | 83 | |
| ovarian tumor | 0 / 76682 | 0 | |
| pancreatic tumor | 1 / 104616 | 9 | |
| primitive neuroectodermal tumor of the CNS | 19 / 125680 | 151 | |
| prostate cancer | 4 / 102680 | 38 | |
| retinoblastoma | 6 / 46356 | 129 | |
| skin tumor | 1 / 124949 | 8 | |
| soft tissue/muscle tissue tumor | 2 / 125191 | 15 | |
| uterine tumor | 0 / 90257 | 0 |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 0 / 13106 | 0 | |
| adrenal gland | 2 / 33197 | 60 | |
| ascites | 0 / 40015 | 0 | |
| bladder | 0 / 29757 | 0 | |
| blood | 3 / 123478 | 24 | |
| bone | 2 / 71655 | 27 | |
| bone marrow | 0 / 48801 | 0 | |
| brain | 47 / 1100989 | 42 | |
| cervix | 0 / 48171 | 0 | |
| connective tissue | 2 / 149255 | 13 | |
| ear | 171 / 16212 | 10547 |  |
| embryonic tissue | 6 / 215722 | 27 | |
| esophagus | 0 / 20209 | 0 | |
| eye | 11 / 211054 | 52 | |
| heart | 0 / 89626 | 0 | |
| intestine | 3 / 234472 | 12 | |
| kidney | 5 / 211777 | 23 | |
| larynx | 1 / 24145 | 41 | |
| liver | 6 / 207743 | 28 | |
| lung | 17 / 336974 | 50 | |
| lymph | 0 / 44270 | 0 | |
| lymph node | 2 / 91610 | 21 | |
| mammary gland | 1 / 153271 | 6 | |
| mouth | 3 / 67052 | 44 | |
| muscle | 0 / 107715 | 0 | |
| nerve | 1 / 15768 | 63 | |
| ovary | 0 / 102051 | 0 | |
| pancreas | 5 / 214812 | 23 | |
| parathyroid | 0 / 20539 | 0 | |
| pharynx | 0 / 41328 | 0 | |
| pituitary gland | 1 / 16585 | 60 | |
| placenta | 5 / 280825 | 17 | |
| prostate | 5 / 189345 | 26 | |
| salivary gland | 0 / 20155 | 0 | |
| skin | 1 / 210574 | 4 | |
| spleen | 1 / 53952 | 18 | |
| stomach | 3 / 96619 | 31 | |
| testis | 7 / 330442 | 21 | |
| thymus | 1 / 81131 | 12 | |
| thyroid | 0 / 47473 | 0 | |
| tonsil | 1 / 16999 | 58 | |
| trachea | 0 / 52413 | 0 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 1 / 232878 | 4 | |
| vascular | 0 / 51780 | 0 |
- Microarray Platform: GeneAtlas U133A, gcrma
- Affymatrix Probe ID: 205229_s_at
| Cell line | Expression level | Expression bar |
|---|---|---|
| ||
| 721_B_lymphoblasts | 45.15 | |
| Adipocyte | 5.85 | |
| AdrenalCortex | 6.55 | |
| Adrenalgland | 5.2 | |
| Amygdala | 8.35 | |
| Appendix | 6.35 | |
| AtrioventricularNode | 5.2 | |
| BDCA4+_DentriticCells | 7.5 | |
| Bonemarrow | 5.95 | |
| BronchialEpithelialCells | 5.75 | |
| CD105+_Endothelial | 11.55 | |
| CD14+_Monocytes | 6.3 | |
| CD19+_BCells(neg._sel.) | 15.25 | |
| CD33+_Myeloid | 7.45 | |
| CD34+ | 127.7 | |
| CD4+_Tcells | 6.1 | |
| CD56+_NKCells | 6.7 | |
| CD71+_EarlyErythroid | 5.55 | |
| CD8+_Tcells | 5.5 | |
| CardiacMyocytes | 8.2 | |
| Caudatenucleus | 535.25 | |
| Cerebellum | 4.85 | |
| CerebellumPeduncles | 7 | |
| CiliaryGanglion | 4.7 | |
| CingulateCortex | 6.2 | |
| Colorectaladenocarcinoma | 5.95 | |
| DorsalRootGanglion | 5.05 | |
| FetalThyroid | 5.85 | |
| Fetalbrain | 11.15 | |
| Fetalliver | 5.2 | |
| Fetallung | 4.8 | |
| GlobusPallidus | 4.45 | |
| Heart | 8.1 | |
| Hypothalamus | 11 | |
| Kidney | 5.1 | |
| Leukemia_chronicMyelogenousK-562 | 177.25 | |
| Leukemia_promyelocytic-HL-60 | 5.25 | |
| Leukemialymphoblastic(MOLT-4) | 4.8 | |
| Liver | 8.05 | |
| Lung | 6.55 | |
| Lymphnode | 5.35 | |
| Lymphoma_burkitts(Daudi) | 7.7 | |
| Lymphoma_burkitts(Raji) | 8.5 | |
| MedullaOblongata | 22.75 | |
| OccipitalLobe | 5.4 | |
| OlfactoryBulb | 4.7 | |
| Ovary | 4.3 | |
| Pancreas | 5.05 | |
| PancreaticIslet | 7.7 | |
| ParietalLobe | 6.35 | |
| Pituitary | 18.25 | |
| Placenta | 6 | |
| Pons | 9.05 | |
| PrefrontalCortex | 7.2 | |
| Prostate | 7.55 | |
| Salivarygland | 4.95 | |
| SkeletalMuscle | 7.35 | |
| Skin | 5.15 | |
| SmoothMuscle | 6.75 | |
| Spinalcord | 6.65 | |
| SubthalamicNucleus | 5.55 | |
| SuperiorCervicalGanglion | 7.15 | |
| TemporalLobe | 5.45 | |
| Testis | 5.15 | |
| TestisGermCell | 4.9 | |
| TestisIntersitial | 5.05 | |
| TestisLeydigCell | 6.05 | |
| TestisSeminiferousTubule | 5.1 | |
| Thalamus | 25.5 | |
| Thymus | 4.65 | |
| Thyroid | 7.2 | |
| Tongue | 6.1 | |
| Tonsil | 5.95 | |
| Trachea | 4.95 | |
| TrigeminalGanglion | 6.55 | |
| Uterus | 4.8 | |
| UterusCorpus | 5.4 | |
| WholeBlood | 6.45 | |
| Wholebrain | 5.15 | |
| colon | 5.95 | |
| pineal_day | 7.22 | |
| pineal_night | 7.32 | |
| retina | 7.25 | |
| small_intestine | 5.8 | |
- Probe name: CUST_12_PI416408490
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 3.11 ± 1.16 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 3.59 ± 1.11 | |
| Basal Part of Pons | 3.17 ± 1.07 | |
| Cerebellar Cortex | 2.27 ± 0.4 | |
| Cerebellar Nuclei | 2.89 ± 0.76 | |
| Claustrum | 3.25 ± 0.64 | |
| Epithalamus | 3.01 ± 1.06 | |
| Frontal Lobe | 2.8 ± 0.95 | |
| Globus Pallidus | 2.59 ± 0.66 | |
| Hypothalamus | 3.53 ± 1.5 | |
| Insula | 3.12 ± 1 | |
| Limbic Lobe | 2.77 ± 0.82 | |
| Mesencephalon | 3.3 ± 1.12 | |
| Myelencephalon | 3.02 ± 0.91 | |
| Occipital Lobe | 2.49 ± 0.9 | |
| Parietal Lobe | 2.6 ± 0.95 | |
| Pontine Tegmentum | 2.91 ± 1.15 | |
| Striatum | 6.06 ± 0.91 | |
| Subthalamus | 3.04 ± 0.97 | |
| Temporal Lobe | 2.98 ± 0.9 | |
| Thalamus | 3.06 ± 0.83 | |
| White Matter | 2.16 ± 0.24 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Coch | CB | Cerebellum | 7.88 | |
| 11.97 | | |||
| Coch | CTX | Cerebral cortex | 52.08 | |
| 46.96 | | |||
| Coch | HIP | Hippocampal region | 2.93 | |
| 5.84 | | |||
| Coch | HPF | Hippocampal formation | 4.75 | |
| 6.89 | | |||
| Coch | HY | Hypothalamus | 8.69 | |
| 9.5 | | |||
| Coch | LSX | Lateral septal complex | 8.78 | |
| 7.55 | | |||
| Coch | MB | Midbrain | 9.26 | |
| 11.81 | | |||
| Coch | MY | Medulla | 7.03 | |
| 12.66 | | |||
| Coch | OLF | Olfactory bulb | 26.62 | |
| 34.03 | | |||
| Coch | P | Pons | 3.89 | |
| 5.5 | | |||
| Coch | PAL | Pallidum | 8.59 | |
| 9.82 | | |||
| Coch | RHP | Retrohippocampal region | 7.25 | |
| 7.99 | | |||
| Coch | sAMY | Striatum-like amygdalar nuclei | 7.87 | |
| 9.26 | | |||
| Coch | STR | Striatum | 74.44 | |
| 79.29 | | |||
| Coch | STRd | Striatum dorsal region | 100 | |
| 100 | | |||
| Coch | STRv | Striatum ventral region | 6.13 | |
| 4.48 | | |||
| Coch | TH | Thalamus | 27.54 | |
| 36.66 | |
| Peptide Name | Peptide Lengh | Peptide Start | Peptide End | Peptide Sequence | Source |
|---|---|---|---|---|---|
| PAp00377570 | 35 | 46 | 80 | ADVLCPGGCPLEEFSVYGNIVYASVSSICGAAVHR | Peptide Atlas |