AutismKB 2.0

Annotation Detail for QSOX2


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Basic Information Top
Gene Symbol:QSOX2 ( DKFZp762A2013,QSCN6L1,SOXN )
Gene Full Name: quiescin Q6 sulfhydryl oxidase 2
Band: 9q34.3
Quick LinksEntrez ID:169714; OMIM: 612860; Uniprot ID:QSOX2_HUMAN; ENSEMBL ID: ENSG00000165661; HGNC ID: 30249
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body5 / 7076170
blastocyst2 / 6231932
fetus9 / 56401215
neonate0 / 310970 
infant1 / 2362042
juvenile0 / 555560 
adult21 / 193912110
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor1 / 3436629
chondrosarcoma0 / 828230 
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor4 / 11936933
germ cell tumor6 / 26384522
glioma2 / 10688318
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia7 / 9584273
liver tumor1 / 9635910
lung tumor2 / 10312719
lymphoma2 / 7175527
non-neoplasia0 / 972500 
normal52 / 336030715
ovarian tumor1 / 7668213
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS4 / 12568031
prostate cancer1 / 1026809
retinoblastoma4 / 4635686
skin tumor5 / 12494940
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites2 / 4001549
bladder0 / 297570 
blood2 / 12347816
bone1 / 7165513
bone marrow1 / 4880120
brain7 / 11009896
cervix1 / 4817120
connective tissue0 / 1492550 
ear2 / 16212123
embryonic tissue9 / 21572241
esophagus0 / 202090 
eye11 / 21105452
heart0 / 896260 
intestine10 / 23447242
kidney0 / 2117770 
larynx0 / 241450 
liver1 / 2077434
lung5 / 33697414
lymph1 / 4427022
lymph node7 / 9161076
mammary gland1 / 1532716
mouth0 / 670520 
muscle0 / 1077150 
nerve1 / 1576863
ovary3 / 10205129
pancreas6 / 21481227
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta2 / 2808257
prostate1 / 1893455
salivary gland0 / 201550 
skin5 / 21057423
spleen4 / 5395274
stomach0 / 966190 
testis6 / 33044218
thymus1 / 8113112
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus2 / 2328788
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P263682
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.1 ± 0.69
Basal Forebrain3.95 ± 0.8
Basal Part of Pons3.87 ± 0.44
Cerebellar Cortex4.48 ± 0.31
Cerebellar Nuclei3.89 ± 0.6
Claustrum3.96 ± 0.63
Epithalamus4.23 ± 0.63
Frontal Lobe3.66 ± 0.64
Globus Pallidus3.57 ± 0.92
Hypothalamus3.79 ± 0.5
Insula3.85 ± 0.56
Limbic Lobe4.04 ± 0.62
Mesencephalon3.86 ± 0.58
Myelencephalon3.86 ± 0.6
Occipital Lobe4.23 ± 0.63
Parietal Lobe3.92 ± 0.59
Pontine Tegmentum3.99 ± 0.73
Striatum4.35 ± 0.64
Subthalamus4.01 ± 0.28
Temporal Lobe3.89 ± 0.54
Thalamus3.82 ± 0.58
White Matter3.99 ± 1.13
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Qscn6l1CBCerebellum20.15
21.64
Qscn6l1CTXCerebral cortex52.52
41.04
Qscn6l1HIPHippocampal region40.45
68.91
Qscn6l1HPFHippocampal formation42.77
55.12
Qscn6l1HYHypothalamus24.7
19.82
Qscn6l1LSXLateral septal complex66.66
51.62
Qscn6l1MBMidbrain21.47
18.46
Qscn6l1MYMedulla22.81
22.86
Qscn6l1OLFOlfactory bulb66.99
63.6
Qscn6l1PPons18.43
18.02
Qscn6l1PALPallidum24.21
22.15
Qscn6l1RHPRetrohippocampal region46.04
39.86
Qscn6l1sAMYStriatum-like amygdalar nuclei36.19
26.63
Qscn6l1STRStriatum50.39
37.46
Qscn6l1STRdStriatum dorsal region48.63
35.82
Qscn6l1STRvStriatum ventral region59.67
44.68
Qscn6l1THThalamus17.4
15.99
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00041450 33 435 467 LFHTLTVEASTHPDALVGTGFEDDPQAVLQTMR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018