AutismKB 2.0

Annotation Detail for CLYBL


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Basic Information Top
Gene Symbol:CLYBL ( CLB,bA134O15.1 )
Gene Full Name: citrate lyase beta like
Band: 13q32.3
Quick LinksEntrez ID:171425; OMIM: 609686; Uniprot ID:CLYBL_HUMAN; ENSEMBL ID: ENSG00000125246; HGNC ID: 18355
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst1 / 6231916
fetus9 / 56401215
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult39 / 193912120
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma3 / 8282336
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor1 / 2638453
glioma1 / 1068839
head and neck tumor0 / 1363020 
kidney tumor1 / 6895914
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor3 / 10312729
lymphoma1 / 7175513
non-neoplasia0 / 972500 
normal56 / 336030716
ovarian tumor2 / 7668226
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS2 / 12568015
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor1 / 1249498
soft tissue/muscle tissue tumor3 / 12519123
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone5 / 7165569
bone marrow0 / 488010 
brain15 / 110098913
cervix0 / 481710 
connective tissue3 / 14925520
ear0 / 162120 
embryonic tissue1 / 2157224
esophagus0 / 202090 
eye3 / 21105414
heart1 / 8962611
intestine1 / 2344724
kidney15 / 21177770
larynx0 / 241450 
liver3 / 20774314
lung6 / 33697417
lymph0 / 442700 
lymph node2 / 9161021
mammary gland7 / 15327145
mouth0 / 670520 
muscle1 / 1077159
nerve0 / 157680 
ovary2 / 10205119
pancreas7 / 21481232
parathyroid1 / 2053948
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta1 / 2808253
prostate1 / 1893455
salivary gland0 / 201550 
skin2 / 2105749
spleen0 / 539520 
stomach1 / 9661910
testis3 / 3304429
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus2 / 2328788
vascular1 / 5178019
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_849_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.81 ± 0.6
Basal Forebrain3.98 ± 0.33
Basal Part of Pons3.54 ± 0.54
Cerebellar Cortex4.37 ± 0.35
Cerebellar Nuclei3.77 ± 0.4
Claustrum3.9 ± 0.55
Epithalamus5.33 ± 0.61
Frontal Lobe3.88 ± 0.55
Globus Pallidus4.06 ± 0.52
Hypothalamus4.1 ± 0.39
Insula3.79 ± 0.46
Limbic Lobe3.85 ± 0.56
Mesencephalon4.04 ± 0.42
Myelencephalon4.02 ± 0.55
Occipital Lobe4.11 ± 0.49
Parietal Lobe3.99 ± 0.54
Pontine Tegmentum4.15 ± 0.6
Striatum4 ± 0.56
Subthalamus4.06 ± 0.2
Temporal Lobe4.09 ± 0.53
Thalamus4.2 ± 0.56
White Matter3.14 ± 0.74
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
ClyblCBCerebellum4.49
4.92
ClyblCTXCerebral cortex4.42
3.98
ClyblHIPHippocampal region7.73
7.64
ClyblHPFHippocampal formation7.49
6.72
ClyblHYHypothalamus0.62
0.73
ClyblLSXLateral septal complex0.63
0.62
ClyblMBMidbrain1.63
1.99
ClyblMYMedulla3.45
4.74
ClyblOLFOlfactory bulb2.27
2.87
ClyblPPons3.96
4.98
ClyblPALPallidum0.32
0.25
ClyblRHPRetrohippocampal region7.17
5.29
ClyblsAMYStriatum-like amygdalar nuclei0.03
0
ClyblSTRStriatum0.2
0.22
ClyblSTRdStriatum dorsal region0.11
0.09
ClyblSTRvStriatum ventral region0.31
0.51
ClyblTHThalamus3.31
2.81
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018