Annotation Detail for SEPT1
Basic Information Top
| Gene Symbol: | SEPT1 ( DIFF6,LARP,MGC20394,PNUTL3,SEP1 ) |
|---|---|
| Gene Full Name: | septin 1 |
| Band: | 16p11.2 |
| Quick Links | Entrez ID:1731; OMIM: 612897; Uniprot ID:SEPT1_HUMAN; ENSEMBL ID: ENSG00000180096; HGNC ID: 2879 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.632176
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 0 / 70761 | 0 | |
| blastocyst | 0 / 62319 | 0 | |
| fetus | 12 / 564012 | 21 |  |
| neonate | 0 / 31097 | 0 | |
| infant | 0 / 23620 | 0 | |
| juvenile | 9 / 55556 | 161 |  |
| adult | 41 / 1939121 | 21 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 0 / 17475 | 0 | |
| breast (mammary gland) tumor | 0 / 94178 | 0 | |
| cervical tumor | 0 / 34366 | 0 | |
| chondrosarcoma | 3 / 82823 | 36 | |
| colorectal tumor | 0 / 114246 | 0 | |
| esophageal tumor | 0 / 17290 | 0 | |
| gastrointestinal tumor | 0 / 119369 | 0 | |
| germ cell tumor | 1 / 263845 | 3 |  |
| glioma | 1 / 106883 | 9 | |
| head and neck tumor | 0 / 136302 | 0 | |
| kidney tumor | 1 / 68959 | 14 | |
| leukemia | 17 / 95842 | 177 | |
| liver tumor | 0 / 96359 | 0 | |
| lung tumor | 1 / 103127 | 9 | |
| lymphoma | 15 / 71755 | 209 |  |
| non-neoplasia | 1 / 97250 | 10 | |
| normal | 86 / 3360307 | 25 | |
| ovarian tumor | 0 / 76682 | 0 | |
| pancreatic tumor | 2 / 104616 | 19 | |
| primitive neuroectodermal tumor of the CNS | 0 / 125680 | 0 | |
| prostate cancer | 1 / 102680 | 9 | |
| retinoblastoma | 0 / 46356 | 0 | |
| skin tumor | 0 / 124949 | 0 | |
| soft tissue/muscle tissue tumor | 0 / 125191 | 0 | |
| uterine tumor | 0 / 90257 | 0 |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 0 / 13106 | 0 | |
| adrenal gland | 0 / 33197 | 0 | |
| ascites | 0 / 40015 | 0 | |
| bladder | 0 / 29757 | 0 | |
| blood | 25 / 123478 | 202 | |
| bone | 1 / 71655 | 13 | |
| bone marrow | 0 / 48801 | 0 | |
| brain | 3 / 1100989 | 2 | |
| cervix | 0 / 48171 | 0 | |
| connective tissue | 3 / 149255 | 20 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 1 / 215722 | 4 | |
| esophagus | 0 / 20209 | 0 | |
| eye | 3 / 211054 | 14 | |
| heart | 1 / 89626 | 11 | |
| intestine | 1 / 234472 | 4 | |
| kidney | 3 / 211777 | 14 | |
| larynx | 0 / 24145 | 0 | |
| liver | 4 / 207743 | 19 | |
| lung | 3 / 336974 | 8 | |
| lymph | 7 / 44270 | 158 | |
| lymph node | 21 / 91610 | 229 | |
| mammary gland | 0 / 153271 | 0 | |
| mouth | 0 / 67052 | 0 | |
| muscle | 0 / 107715 | 0 | |
| nerve | 0 / 15768 | 0 | |
| ovary | 0 / 102051 | 0 | |
| pancreas | 2 / 214812 | 9 | |
| parathyroid | 0 / 20539 | 0 | |
| pharynx | 0 / 41328 | 0 | |
| pituitary gland | 0 / 16585 | 0 | |
| placenta | 2 / 280825 | 7 | |
| prostate | 1 / 189345 | 5 | |
| salivary gland | 0 / 20155 | 0 | |
| skin | 0 / 210574 | 0 | |
| spleen | 7 / 53952 | 129 | |
| stomach | 0 / 96619 | 0 | |
| testis | 1 / 330442 | 3 | |
| thymus | 39 / 81131 | 480 | |
| thyroid | 0 / 47473 | 0 | |
| tonsil | 2 / 16999 | 117 | |
| trachea | 0 / 52413 | 0 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 3 / 232878 | 12 | |
| vascular | 0 / 51780 | 0 |
Microarray in - Probe name: CUST_9059_PI416261804
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 2.21 ± 1.01 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 2.04 ± 0.64 | |
| Basal Part of Pons | 1.51 ± 0.53 | |
| Cerebellar Cortex | 1.92 ± 0.83 | |
| Cerebellar Nuclei | 2.1 ± 0.69 | |
| Claustrum | 2.77 ± 0.86 | |
| Epithalamus | 1.52 ± 0.81 | |
| Frontal Lobe | 1.63 ± 0.7 | |
| Globus Pallidus | 2.23 ± 0.31 | |
| Hypothalamus | 1.89 ± 0.68 | |
| Insula | 1.63 ± 0.48 | |
| Limbic Lobe | 1.8 ± 0.64 | |
| Mesencephalon | 1.99 ± 0.7 | |
| Myelencephalon | 1.88 ± 0.72 | |
| Occipital Lobe | 1.86 ± 0.65 | |
| Parietal Lobe | 1.93 ± 0.74 | |
| Pontine Tegmentum | 1.88 ± 0.73 | |
| Striatum | 1.83 ± 0.49 | |
| Subthalamus | 2.03 ± 0.75 | |
| Temporal Lobe | 1.8 ± 0.87 | |
| Thalamus | 1.79 ± 0.58 | |
| White Matter | 2.05 ± 0.24 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Sept1 | CB | Cerebellum | 17.94 | |
| 24.68 | | |||
| Sept1 | CTX | Cerebral cortex | 35.79 | |
| 28.75 | | |||
| Sept1 | HIP | Hippocampal region | 8.46 | |
| 8.31 | | |||
| Sept1 | HPF | Hippocampal formation | 7.66 | |
| 7.08 | | |||
| Sept1 | HY | Hypothalamus | 1.93 | |
| 1.51 | | |||
| Sept1 | LSX | Lateral septal complex | 1.91 | |
| 1.3 | | |||
| Sept1 | MB | Midbrain | 8.51 | |
| 8.76 | | |||
| Sept1 | MY | Medulla | 14.68 | |
| 17.25 | | |||
| Sept1 | OLF | Olfactory bulb | 24.86 | |
| 21.4 | | |||
| Sept1 | P | Pons | 6.52 | |
| 8.22 | | |||
| Sept1 | PAL | Pallidum | 5.22 | |
| 4.91 | | |||
| Sept1 | RHP | Retrohippocampal region | 6.35 | |
| 5.42 | | |||
| Sept1 | sAMY | Striatum-like amygdalar nuclei | 4.4 | |
| 3.27 | | |||
| Sept1 | STR | Striatum | 5.93 | |
| 4.51 | | |||
| Sept1 | STRd | Striatum dorsal region | 4.6 | |
| 3.7 | | |||
| Sept1 | STRv | Striatum ventral region | 14.26 | |
| 9.54 | | |||
| Sept1 | TH | Thalamus | 5.35 | |
| 4.89 | |
| Peptide Name | Peptide Lengh | Peptide Start | Peptide End | Peptide Sequence | Source |
|---|---|---|---|---|---|
| SEPT1_HUMAN_109 | 11 | 109 | 119 | FIEEQFEQYLR | PRIDE |
| SEPT1_HUMAN_163 | 9 | 163 | 171 | VNIIPVIGK | PRIDE |
| SEPT1_HUMAN_171 | 13 | 171 | 183 | ADALMPQETQALK | PRIDE |
| SEPT1_HUMAN_23 | 16 | 23 | 38 | GFDFTLMVAGESGLGK | PRIDE |
| SEPT1_HUMAN_278 | 12 | 278 | 289 | EVTHDLLYEGYR | PRIDE |
| SEPT1_HUMAN_279 | 12 | 279 | 290 | EVTHDLLYEGYR | PRIDE |
| SEPT1_HUMAN_38 | 16 | 38 | 53 | STLINSLFLTNLYEDR | PRIDE |
| SEPT1_HUMAN_4 | 14 | 4 | 17 | EYVGFAALPNQLHR | PRIDE |
| SEPT1_HUMAN_55 | 8 | 55 | 62 | QVPEASAR | PRIDE |
| SEPT1_HUMAN_85 | 24 | 85 | 108 | LTLVDTPGFGDSVDCSDCWLPVVK | PRIDE |