AutismKB 2.0

Annotation Detail for DNAH6


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Basic Information Top
Gene Symbol:DNAH6 ( DKFZp667K087,DNHL1,Dnahc6,FLJ23529,FLJ37357,HL-2,HL2,KIAA1697,MGC132544,MGC141984,MGC177197 )
Gene Full Name: dynein, axonemal, heavy chain 6
Band: 2p11.2
Quick LinksEntrez ID:1768; OMIM: 603336; Uniprot ID:DYH6_HUMAN; ENSEMBL ID: ENSG00000115423; HGNC ID: 2951
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus2 / 5640123
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult11 / 19391215
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma2 / 8282324
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor1 / 2638453
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor1 / 6895914
leukemia0 / 958420 
liver tumor3 / 9635931
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal48 / 336030714
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor1 / 1249498
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor4 / 9025744
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone2 / 7165527
bone marrow0 / 488010 
brain8 / 11009897
cervix0 / 481710 
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye0 / 2110540 
heart0 / 896260 
intestine1 / 2344724
kidney1 / 2117774
larynx0 / 241450 
liver3 / 20774314
lung3 / 3369748
lymph0 / 442700 
lymph node1 / 9161010
mammary gland1 / 1532716
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas1 / 2148124
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland1 / 1658560
placenta0 / 2808250 
prostate1 / 1893455
salivary gland0 / 201550 
skin1 / 2105744
spleen1 / 5395218
stomach0 / 966190 
testis2 / 3304426
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea3 / 5241357
umbilical cord0 / 136800 
uterus4 / 23287817
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 215341_at
Cell line Expression level Expression bar
721_B_lymphoblasts27.55
Adipocyte38.2
AdrenalCortex43.9
Adrenalgland56.2
Amygdala39.95
Appendix39.05
AtrioventricularNode30.65
BDCA4+_DentriticCells11.65
Bonemarrow38.45
BronchialEpithelialCells36.5
CD105+_Endothelial19.35
CD14+_Monocytes13.95
CD19+_BCells(neg._sel.)26.75
CD33+_Myeloid19.85
CD34+13.5
CD4+_Tcells30.75
CD56+_NKCells21.1
CD71+_EarlyErythroid29.1
CD8+_Tcells20.6
CardiacMyocytes52.1
Caudatenucleus64.7
Cerebellum61.75
CerebellumPeduncles43.95
CiliaryGanglion27.55
CingulateCortex58.55
Colorectaladenocarcinoma38.65
DorsalRootGanglion30.45
FetalThyroid37.35
Fetalbrain38.25
Fetalliver39.65
Fetallung31.4
GlobusPallidus28.75
Heart50.2
Hypothalamus41.7
Kidney51.75
Leukemia_chronicMyelogenousK-56234.85
Leukemia_promyelocytic-HL-6034.25
Leukemialymphoblastic(MOLT-4)31
Liver51.9
Lung41.95
Lymphnode36.6
Lymphoma_burkitts(Daudi)52.3
Lymphoma_burkitts(Raji)55.05
MedullaOblongata34.95
OccipitalLobe34.55
OlfactoryBulb30.45
Ovary25.95
Pancreas31.1
PancreaticIslet39.2
ParietalLobe58.95
Pituitary45.1
Placenta39.75
Pons37.05
PrefrontalCortex48.1
Prostate36.65
Salivarygland31
SkeletalMuscle46
Skin30.65
SmoothMuscle36.8
Spinalcord44.05
SubthalamicNucleus35.75
SuperiorCervicalGanglion44.85
TemporalLobe34.65
Testis46.15
TestisGermCell39
TestisIntersitial32.45
TestisLeydigCell50.4
TestisSeminiferousTubule45.85
Thalamus39.45
Thymus30.2
Thyroid47.6
Tongue38.3
Tonsil37.55
Trachea33.05
TrigeminalGanglion39.25
Uterus25.2
UterusCorpus35.1
WholeBlood41.75
Wholebrain32.25
colon38.65
pineal_day41.38
pineal_night38.72
retina46.4
small_intestine37.25
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P324605
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.54 ± 0.71
Basal Forebrain3.13 ± 0.45
Basal Part of Pons2.91 ± 0.68
Cerebellar Cortex2.6 ± 0.36
Cerebellar Nuclei2.83 ± 0.66
Claustrum3.48 ± 0.71
Epithalamus5.84 ± 1.24
Frontal Lobe3.29 ± 0.92
Globus Pallidus2.86 ± 0.64
Hypothalamus3.4 ± 0.48
Insula3.62 ± 0.72
Limbic Lobe3.62 ± 0.95
Mesencephalon3.51 ± 0.95
Myelencephalon3.48 ± 1.01
Occipital Lobe3.09 ± 0.96
Parietal Lobe3.23 ± 1.16
Pontine Tegmentum3.39 ± 0.84
Striatum5.45 ± 0.5
Subthalamus2.82 ± 0.72
Temporal Lobe3.53 ± 0.75
Thalamus3.04 ± 0.62
White Matter2.67 ± 0.66
Mouse Brain ISH
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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