Annotation Detail for DYNC1H1
Basic Information Top
Gene Symbol: | DYNC1H1 ( DHC1,DHC1a,DKFZp686P2245,DNCH1,DNCL,DNECL,DYHC,Dnchc1,HL-3,KIAA0325,p22 ) |
---|---|
Gene Full Name: | dynein, cytoplasmic 1, heavy chain 1 |
Band: | 14q32.31 |
Quick Links | Entrez ID:1778; OMIM: 600112; Uniprot ID:DYHC1_HUMAN; ENSEMBL ID: ENSG00000197102; HGNC ID: 2961 |
Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.614080
Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
---|---|---|---|
embryoid body | 0 / 70761 | 0 | |
blastocyst | 0 / 62319 | 0 | |
fetus | 0 / 564012 | 0 | |
neonate | 0 / 31097 | 0 | |
infant | 0 / 23620 | 0 | |
juvenile | 0 / 55556 | 0 | |
adult | 2 / 1939121 | 1 |
Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
---|---|---|---|
adrenal tumor | 0 / 12794 | 0 | |
bladder carcinoma | 0 / 17475 | 0 | |
breast (mammary gland) tumor | 0 / 94178 | 0 | |
cervical tumor | 0 / 34366 | 0 | |
chondrosarcoma | 0 / 82823 | 0 | |
colorectal tumor | 0 / 114246 | 0 | |
esophageal tumor | 0 / 17290 | 0 | |
gastrointestinal tumor | 0 / 119369 | 0 | |
germ cell tumor | 4 / 263845 | 15 | |
glioma | 0 / 106883 | 0 | |
head and neck tumor | 1 / 136302 | 7 | |
kidney tumor | 0 / 68959 | 0 | |
leukemia | 0 / 95842 | 0 | |
liver tumor | 0 / 96359 | 0 | |
lung tumor | 0 / 103127 | 0 | |
lymphoma | 0 / 71755 | 0 | |
non-neoplasia | 0 / 97250 | 0 | |
normal | 2 / 3360307 | 0 | |
ovarian tumor | 0 / 76682 | 0 | |
pancreatic tumor | 0 / 104616 | 0 | |
primitive neuroectodermal tumor of the CNS | 0 / 125680 | 0 | |
prostate cancer | 0 / 102680 | 0 | |
retinoblastoma | 1 / 46356 | 21 | |
skin tumor | 0 / 124949 | 0 | |
soft tissue/muscle tissue tumor | 0 / 125191 | 0 | |
uterine tumor | 0 / 90257 | 0 |
Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
---|---|---|---|
adipose tissue | 0 / 13106 | 0 | |
adrenal gland | 0 / 33197 | 0 | |
ascites | 0 / 40015 | 0 | |
bladder | 0 / 29757 | 0 | |
blood | 0 / 123478 | 0 | |
bone | 0 / 71655 | 0 | |
bone marrow | 0 / 48801 | 0 | |
brain | 0 / 1100989 | 0 | |
cervix | 0 / 48171 | 0 | |
connective tissue | 0 / 149255 | 0 | |
ear | 0 / 16212 | 0 | |
embryonic tissue | 0 / 215722 | 0 | |
esophagus | 0 / 20209 | 0 | |
eye | 2 / 211054 | 9 | |
heart | 0 / 89626 | 0 | |
intestine | 0 / 234472 | 0 | |
kidney | 1 / 211777 | 4 | |
larynx | 0 / 24145 | 0 | |
liver | 0 / 207743 | 0 | |
lung | 2 / 336974 | 5 | |
lymph | 0 / 44270 | 0 | |
lymph node | 0 / 91610 | 0 | |
mammary gland | 0 / 153271 | 0 | |
mouth | 0 / 67052 | 0 | |
muscle | 0 / 107715 | 0 | |
nerve | 0 / 15768 | 0 | |
ovary | 0 / 102051 | 0 | |
pancreas | 0 / 214812 | 0 | |
parathyroid | 0 / 20539 | 0 | |
pharynx | 0 / 41328 | 0 | |
pituitary gland | 0 / 16585 | 0 | |
placenta | 0 / 280825 | 0 | |
prostate | 0 / 189345 | 0 | |
salivary gland | 1 / 20155 | 49 | |
skin | 0 / 210574 | 0 | |
spleen | 0 / 53952 | 0 | |
stomach | 0 / 96619 | 0 | |
testis | 0 / 330442 | 0 | |
thymus | 0 / 81131 | 0 | |
thyroid | 0 / 47473 | 0 | |
tonsil | 0 / 16999 | 0 | |
trachea | 0 / 52413 | 0 | |
umbilical cord | 0 / 13680 | 0 | |
uterus | 0 / 232878 | 0 | |
vascular | 0 / 51780 | 0 |
- Microarray Platform: GeneAtlas U133A, gcrma
- Affymatrix Probe ID: 211928_at
Cell line | Expression level | Expression bar |
---|---|---|
721_B_lymphoblasts | 285.55 | |
Adipocyte | 228.15 | |
AdrenalCortex | 76.05 | |
Adrenalgland | 57 | |
Amygdala | 378.85 | |
Appendix | 53.3 | |
AtrioventricularNode | 57.35 | |
BDCA4+_DentriticCells | 237.7 | |
Bonemarrow | 40.65 | |
BronchialEpithelialCells | 300.5 | |
CD105+_Endothelial | 180.2 | |
CD14+_Monocytes | 269.85 | |
CD19+_BCells(neg._sel.) | 105.8 | |
CD33+_Myeloid | 282.45 | |
CD34+ | 330.5 | |
CD4+_Tcells | 334.5 | |
CD56+_NKCells | 269.3 | |
CD71+_EarlyErythroid | 78.4 | |
CD8+_Tcells | 273.8 | |
CardiacMyocytes | 109.6 | |
Caudatenucleus | 253.15 | |
Cerebellum | 210.9 | |
CerebellumPeduncles | 500.95 | |
CiliaryGanglion | 137.7 | |
CingulateCortex | 577.3 | |
Colorectaladenocarcinoma | 229.35 | |
DorsalRootGanglion | 152.8 | |
FetalThyroid | 163.65 | |
Fetalbrain | 548.4 | |
Fetalliver | 24.7 | |
Fetallung | 96.95 | |
GlobusPallidus | 342.7 | |
Heart | 90.7 | |
Hypothalamus | 687.6 | |
Kidney | 67.85 | |
Leukemia_chronicMyelogenousK-562 | 108.7 | |
Leukemia_promyelocytic-HL-60 | 88.05 | |
Leukemialymphoblastic(MOLT-4) | 82.15 | |
Liver | 35.3 | |
Lung | 167.65 | |
Lymphnode | 74.3 | |
Lymphoma_burkitts(Daudi) | 135.55 | |
Lymphoma_burkitts(Raji) | 290 | |
MedullaOblongata | 392.55 | |
OccipitalLobe | 449.65 | |
OlfactoryBulb | 228.15 | |
Ovary | 58.85 | |
Pancreas | 64.65 | |
PancreaticIslet | 80.35 | |
ParietalLobe | 552.7 | |
Pituitary | 261.55 | |
Placenta | 187.2 | |
Pons | 302.65 | |
PrefrontalCortex | 1082.15 | |
Prostate | 214.1 | |
Salivarygland | 92.1 | |
SkeletalMuscle | 57.9 | |
Skin | 66.8 | |
SmoothMuscle | 297.7 | |
Spinalcord | 392.55 | |
SubthalamicNucleus | 480.8 | |
SuperiorCervicalGanglion | 69.6 | |
TemporalLobe | 372.6 | |
Testis | 126.1 | |
TestisGermCell | 300.65 | |
TestisIntersitial | 163.1 | |
TestisLeydigCell | 84.85 | |
TestisSeminiferousTubule | 158.45 | |
Thalamus | 579.4 | |
Thymus | 121 | |
Thyroid | 173.85 | |
Tongue | 86.4 | |
Tonsil | 73.3 | |
Trachea | 63.7 | |
TrigeminalGanglion | 94.55 | |
Uterus | 199.65 | |
UterusCorpus | 61.05 | |
WholeBlood | 56 | |
Wholebrain | 481.75 | |
colon | 78.5 | |
pineal_day | 508.46 | |
pineal_night | 476.94 | |
retina | 289.175 | |
small_intestine | 89.25 |
Human Whole Brain Microarrayview in Allen Brain Atlas
- Probe name: A_23_P128706
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue | Expression(mean ± stddev) | Expression Bar |
---|---|---|
Amygdala | 11.25 ± 0.49 | |
Basal Forebrain | 11.52 ± 0.26 | |
Basal Part of Pons | 12.21 ± 0.19 | |
Cerebellar Cortex | 11.87 ± 0.23 | |
Cerebellar Nuclei | 11.92 ± 0.32 | |
Claustrum | 11.49 ± 0.45 | |
Epithalamus | 11.49 ± 0.24 | |
Frontal Lobe | 11.88 ± 0.33 | |
Globus Pallidus | 11.12 ± 0.31 | |
Hypothalamus | 11.84 ± 0.26 | |
Insula | 11.85 ± 0.23 | |
Limbic Lobe | 11.63 ± 0.55 | |
Mesencephalon | 11.59 ± 0.39 | |
Myelencephalon | 11.64 ± 0.51 | |
Occipital Lobe | 11.3 ± 0.55 | |
Parietal Lobe | 11.72 ± 0.4 | |
Pontine Tegmentum | 11.62 ± 0.36 | |
Striatum | 11.08 ± 0.4 | |
Subthalamus | 12.05 ± 0.1 | |
Temporal Lobe | 11.87 ± 0.37 | |
Thalamus | 11.7 ± 0.32 | |
White Matter | 11.35 ± 0.25 |
Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
---|---|---|---|---|
Dync1h1 | CB | Cerebellum | 67.04 | |
100 | ||||
Dync1h1 | CTX | Cerebral cortex | 100 | |
100 | ||||
Dync1h1 | HIP | Hippocampal region | 100 | |
100 | ||||
Dync1h1 | HPF | Hippocampal formation | 100 | |
100 | ||||
Dync1h1 | HY | Hypothalamus | 100 | |
100 | ||||
Dync1h1 | LSX | Lateral septal complex | 100 | |
100 | ||||
Dync1h1 | MB | Midbrain | 100 | |
100 | ||||
Dync1h1 | MY | Medulla | 100 | |
100 | ||||
Dync1h1 | OLF | Olfactory bulb | 100 | |
100 | ||||
Dync1h1 | P | Pons | 100 | |
100 | ||||
Dync1h1 | PAL | Pallidum | 100 | |
100 | ||||
Dync1h1 | RHP | Retrohippocampal region | 100 | |
100 | ||||
Dync1h1 | sAMY | Striatum-like amygdalar nuclei | 100 | |
100 | ||||
Dync1h1 | STR | Striatum | 100 | |
100 | ||||
Dync1h1 | STRd | Striatum dorsal region | 100 | |
100 | ||||
Dync1h1 | STRv | Striatum ventral region | 100 | |
100 | ||||
Dync1h1 | TH | Thalamus | 100 | |
100 |
Peptide Name | Peptide Lengh | Peptide Start | Peptide End | Peptide Sequence | Source |
---|---|---|---|---|---|
DYHC1_HUMAN_0 | 0 | 0 | 0 | GIFEALRPLETLPVEGLIR | PRIDE |
DYHC1_HUMAN_0 | 0 | 0 | 0 | VNFLPEIITLSK | PRIDE |
DYHC1_HUMAN_1131 | 18 | 1131 | 1148 | FGQMLGSNMTEFHSQISK | PRIDE |
DYHC1_HUMAN_122 | 15 | 122 | 136 | TPVIDADKPVSSQLR | PRIDE |
DYHC1_HUMAN_1309 | 16 | 1309 | 1324 | QNLDALLNQLKSFPAR | PRIDE |
DYHC1_HUMAN_1361 | 11 | 1361 | 1371 | QNLDALLNQLK | PRIDE |
DYHC1_HUMAN_1585 | 15 | 1585 | 1599 | SPLVMDVLNIQGVQR | PRIDE |
DYHC1_HUMAN_1850 | 16 | 1850 | 1865 | QTDVLQQLSIQMANAK | PRIDE |
DYHC1_HUMAN_1888 | 12 | 1888 | 1899 | CYLTMTQALEAR | PRIDE |
DYHC1_HUMAN_2008 | 18 | 2008 | 2025 | VSPDMAIFITMNPGYAGR | PRIDE |
DYHC1_HUMAN_2384 | 13 | 2384 | 2396 | SIPLDEGEDEAQR | PRIDE |
DYHC1_HUMAN_2399 | 19 | 2399 | 2417 | KGKEDEGEEAASPMLQIQR | PRIDE |
DYHC1_HUMAN_2400 | 18 | 2400 | 2417 | GKEDEGEEAASPMLQIQR | PRIDE |
DYHC1_HUMAN_2402 | 16 | 2402 | 2417 | EDEGEEAASPMLQIQR | PRIDE |
DYHC1_HUMAN_2418 | 18 | 2418 | 2435 | DAATIMQPYFTSNGLVTK | PRIDE |
DYHC1_HUMAN_2436 | 16 | 2436 | 2451 | ALEHAFQLEHIMDLTR | PRIDE |
DYHC1_HUMAN_2602 | 9 | 2602 | 2610 | TMTLFSALR | PRIDE |
DYHC1_HUMAN_2611 | 23 | 2611 | 2633 | ALPDMEVVGLNFSSATTPELLLK | PRIDE |
DYHC1_HUMAN_2685 | 10 | 2685 | 2694 | QMVEHGGFYR | PRIDE |
DYHC1_HUMAN_2990 | 18 | 2990 | 3007 | IAFIMDESNVLDSGFLER | PRIDE |
DYHC1_HUMAN_3061 | 16 | 3061 | 3076 | NLHVVFTMNPSSEGLK | PRIDE |
DYHC1_HUMAN_3191 | 16 | 3191 | 3206 | RSELEEQQMHLNVGLR | PRIDE |
DYHC1_HUMAN_3255 | 12 | 3255 | 3266 | VMSQEIQEQLHK | PRIDE |
DYHC1_HUMAN_3309 | 10 | 3309 | 3318 | SMANPPAAVK | PRIDE |
DYHC1_HUMAN_3430 | 9 | 3430 | 3438 | ANEVEQMIR | PRIDE |
DYHC1_HUMAN_3475 | 12 | 3475 | 3486 | STALLKSLSAER | PRIDE |
DYHC1_HUMAN_355 | 11 | 355 | 365 | QALVAIFTHLR | PRIDE |
DYHC1_HUMAN_3692 | 16 | 3692 | 3707 | QLEKSLLQALNEVKGR | PRIDE |
DYHC1_HUMAN_3874 | 16 | 3874 | 3889 | GMLHQDHITFAMLLAR | PRIDE |
DYHC1_HUMAN_4245 | 11 | 4245 | 4255 | TLMAQSIYGGR | PRIDE |
DYHC1_HUMAN_4288 | 14 | 4288 | 4301 | VDGHKDIQMPDGIR | PRIDE |
DYHC1_HUMAN_4293 | 9 | 4293 | 4301 | DIQMPDGIR | PRIDE |
DYHC1_HUMAN_4366 | 13 | 4366 | 4378 | TDSTSDGRPAWMR | PRIDE |
DYHC1_HUMAN_541 | 11 | 541 | 551 | EGTEAWEAAMK | PRIDE |
DYHC1_HUMAN_577 | 7 | 577 | 583 | NANEMFR | PRIDE |
DYHC1_HUMAN_934 | 21 | 934 | 954 | AEVDMDTDAPQVSHKPGGEPK | PRIDE |
PAp00001491 | 12 | 1888 | 1899 | CYLTMTQALEAR | Peptide Atlas |