AutismKB 2.0

Annotation Detail for DYNC1I1


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:DYNC1I1 ( DNCI1,DNCIC1 )
Gene Full Name: dynein, cytoplasmic 1, intermediate chain 1
Band: 7q21.3
Quick LinksEntrez ID:1780; OMIM: 603772; Uniprot ID:DC1I1_HUMAN; ENSEMBL ID: ENSG00000158560; HGNC ID: 2963
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst1 / 6231916
fetus133 / 564012235
neonate0 / 310970 
infant2 / 2362084
juvenile1 / 5555617
adult28 / 193912114
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor9 / 26384534
glioma0 / 1068830 
head and neck tumor3 / 13630222
kidney tumor11 / 68959159
leukemia1 / 9584210
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia3 / 9725030
normal320 / 336030795
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor3 / 12494924
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow1 / 4880120
brain297 / 1100989269
cervix0 / 481710 
connective tissue2 / 14925513
ear4 / 16212246
embryonic tissue1 / 2157224
esophagus0 / 202090 
eye9 / 21105442
heart0 / 896260 
intestine0 / 2344720 
kidney12 / 21177756
larynx0 / 241450 
liver0 / 2077430 
lung0 / 3369740 
lymph0 / 442700 
lymph node0 / 916100 
mammary gland1 / 1532716
mouth3 / 6705244
muscle0 / 1077150 
nerve1 / 1576863
ovary1 / 1020519
pancreas5 / 21481223
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate3 / 18934515
salivary gland0 / 201550 
skin4 / 21057418
spleen1 / 5395218
stomach0 / 966190 
testis4 / 33044212
thymus2 / 8113124
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus3 / 23287812
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 205348_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts9.9
Adipocyte7.95
AdrenalCortex9.4
Adrenalgland7.15
Amygdala258.2
Appendix11.35
AtrioventricularNode17.3
BDCA4+_DentriticCells8.25
Bonemarrow8.4
BronchialEpithelialCells7.35
CD105+_Endothelial7.65
CD14+_Monocytes7.95
CD19+_BCells(neg._sel.)7.85
CD33+_Myeloid9.4
CD34+9.55
CD4+_Tcells8
CD56+_NKCells8.65
CD71+_EarlyErythroid7.3
CD8+_Tcells7.4
CardiacMyocytes10.25
Caudatenucleus166.55
Cerebellum125.75
CerebellumPeduncles172.7
CiliaryGanglion10.95
CingulateCortex158.1
Colorectaladenocarcinoma7.7
DorsalRootGanglion35.25
FetalThyroid7.7
Fetalbrain631.6
Fetalliver7.7
Fetallung6.75
GlobusPallidus113.7
Heart10.75
Hypothalamus391.7
Kidney6.7
Leukemia_chronicMyelogenousK-5628.15
Leukemia_promyelocytic-HL-607.35
Leukemialymphoblastic(MOLT-4)6.55
Liver13.5
Lung8.3
Lymphnode6.65
Lymphoma_burkitts(Daudi)10.1
Lymphoma_burkitts(Raji)12.25
MedullaOblongata147.15
OccipitalLobe212.6
OlfactoryBulb17.45
Ovary8.35
Pancreas6.75
PancreaticIslet20.95
ParietalLobe190.25
Pituitary32.95
Placenta7.6
Pons119.9
PrefrontalCortex140
Prostate9.65
Salivarygland6.8
SkeletalMuscle10.1
Skin6.85
SmoothMuscle7.65
Spinalcord166
SubthalamicNucleus185.65
SuperiorCervicalGanglion10
TemporalLobe118.1
Testis6.45
TestisGermCell6.8
TestisIntersitial6.4
TestisLeydigCell8.2
TestisSeminiferousTubule6.8
Thalamus216.65
Thymus6.65
Thyroid9.55
Tongue7.85
Tonsil8.15
Trachea6.25
TrigeminalGanglion11.25
Uterus6.1
UterusCorpus8.05
WholeBlood8.25
Wholebrain277
colon7.7
pineal_day239.52
pineal_night244.36
retina90.425
small_intestine7.55
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P221414
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.32 ± 0.68
Basal Forebrain7.44 ± 0.31
Basal Part of Pons8.35 ± 0.26
Cerebellar Cortex8.08 ± 0.36
Cerebellar Nuclei7.67 ± 0.42
Claustrum7.75 ± 0.32
Epithalamus6.66 ± 1.16
Frontal Lobe8.14 ± 0.41
Globus Pallidus6.57 ± 0.58
Hypothalamus8.21 ± 0.34
Insula8.12 ± 0.33
Limbic Lobe8.03 ± 0.62
Mesencephalon7.91 ± 0.65
Myelencephalon7.75 ± 0.74
Occipital Lobe7.09 ± 0.72
Parietal Lobe7.85 ± 0.44
Pontine Tegmentum7.76 ± 0.61
Striatum6.87 ± 0.5
Subthalamus8.48 ± 0.27
Temporal Lobe8.07 ± 0.45
Thalamus7.76 ± 0.34
White Matter6.59 ± 0.25
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Dync1i1CBCerebellum33.74
83.15
Dync1i1CTXCerebral cortex100
100
Dync1i1HIPHippocampal region61.47
100
Dync1i1HPFHippocampal formation81.76
100
Dync1i1HYHypothalamus75.05
74.57
Dync1i1LSXLateral septal complex46.38
36.02
Dync1i1MBMidbrain77.67
89.23
Dync1i1MYMedulla81.06
100
Dync1i1OLFOlfactory bulb100
100
Dync1i1PPons76.17
100
Dync1i1PALPallidum75.51
85.96
Dync1i1RHPRetrohippocampal region100
100
Dync1i1sAMYStriatum-like amygdalar nuclei70.3
62.09
Dync1i1STRStriatum36.04
30.2
Dync1i1STRdStriatum dorsal region26.39
22.51
Dync1i1STRvStriatum ventral region45.89
34.95
Dync1i1THThalamus83.65
86.47
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00063326 20 474 493 AGIGEVFEGHQGPVTGINCH Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved