AutismKB 2.0

Annotation Detail for TRDMT1


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Basic Information Top
Gene Symbol:TRDMT1 ( DMNT2,DNMT2,MHSAIIP,PUMET,RNMT1 )
Gene Full Name: tRNA aspartic acid methyltransferase 1
Band: 10p13
Quick LinksEntrez ID:1787; OMIM: 602478; Uniprot ID:TRDMT_HUMAN; ENSEMBL ID: ENSG00000107614; HGNC ID: 2977
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst2 / 6231932
fetus12 / 56401221
neonate1 / 3109732
infant0 / 236200 
juvenile0 / 555560 
adult30 / 193912115
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor4 / 26384515
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor1 / 6895914
leukemia2 / 9584220
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia2 / 9725020
normal55 / 336030716
ovarian tumor0 / 766820 
pancreatic tumor4 / 10461638
primitive neuroectodermal tumor of the CNS2 / 12568015
prostate cancer0 / 1026800 
retinoblastoma1 / 4635621
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor3 / 12519123
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood1 / 1234788
bone1 / 7165513
bone marrow2 / 4880140
brain11 / 11009899
cervix0 / 481710 
connective tissue2 / 14925513
ear0 / 162120 
embryonic tissue6 / 21572227
esophagus0 / 202090 
eye2 / 2110549
heart1 / 8962611
intestine0 / 2344720 
kidney3 / 21177714
larynx6 / 24145248
liver1 / 2077434
lung1 / 3369742
lymph0 / 442700 
lymph node1 / 9161010
mammary gland5 / 15327132
mouth0 / 670520 
muscle2 / 10771518
nerve0 / 157680 
ovary0 / 1020510 
pancreas6 / 21481227
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta2 / 2808257
prostate1 / 1893455
salivary gland0 / 201550 
skin2 / 2105749
spleen0 / 539520 
stomach0 / 966190 
testis6 / 33044218
thymus1 / 8113112
thyroid0 / 474730 
tonsil0 / 169990 
trachea2 / 5241338
umbilical cord0 / 136800 
uterus2 / 2328788
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 206308_at
Cell line Expression level Expression bar
721_B_lymphoblasts6.4
Adipocyte5.55
AdrenalCortex6.5
Adrenalgland5
Amygdala5.75
Appendix7
AtrioventricularNode4.9
BDCA4+_DentriticCells8.15
Bonemarrow6
BronchialEpithelialCells5.45
CD105+_Endothelial5.65
CD14+_Monocytes6
CD19+_BCells(neg._sel.)6.1
CD33+_Myeloid7.65
CD34+6.8
CD4+_Tcells5.85
CD56+_NKCells6.4
CD71+_EarlyErythroid5.45
CD8+_Tcells5.2
CardiacMyocytes8.3
Caudatenucleus5.15
Cerebellum4.65
CerebellumPeduncles6.9
CiliaryGanglion4.55
CingulateCortex5.95
Colorectaladenocarcinoma5.7
DorsalRootGanglion4.9
FetalThyroid6.7
Fetalbrain5.45
Fetalliver5.05
Fetallung4.5
GlobusPallidus4.4
Heart8.15
Hypothalamus6
Kidney5.05
Leukemia_chronicMyelogenousK-5625.1
Leukemia_promyelocytic-HL-605.05
Leukemialymphoblastic(MOLT-4)4.4
Liver8.15
Lung6.2
Lymphnode4.8
Lymphoma_burkitts(Daudi)7.45
Lymphoma_burkitts(Raji)8.5
MedullaOblongata5.1
OccipitalLobe5.05
OlfactoryBulb4.45
Ovary3.95
Pancreas4.65
PancreaticIslet6.05
ParietalLobe6.35
Pituitary6.55
Placenta5.6
Pons6.2
PrefrontalCortex6.85
Prostate6.5
Salivarygland4.65
SkeletalMuscle7.55
Skin4.8
SmoothMuscle6.85
Spinalcord6.05
SubthalamicNucleus5.35
SuperiorCervicalGanglion10.4
TemporalLobe5.35
Testis4.85
TestisGermCell4.55
TestisIntersitial4.85
TestisLeydigCell6.15
TestisSeminiferousTubule4.85
Thalamus5.85
Thymus4.3
Thyroid6.95
Tongue6
Tonsil5.6
Trachea4.7
TrigeminalGanglion6.75
Uterus4.55
UterusCorpus6.05
WholeBlood6.15
Wholebrain4.55
colon5.7
pineal_day6.88
pineal_night6.86
retina6.825
small_intestine5.4
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_32_P21579
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.19 ± 1
Basal Forebrain1.86 ± 0.4
Basal Part of Pons1.89 ± 0.81
Cerebellar Cortex2.55 ± 0.36
Cerebellar Nuclei1.99 ± 0.73
Claustrum2.21 ± 0.77
Epithalamus2.68 ± 0.86
Frontal Lobe1.66 ± 0.79
Globus Pallidus1.52 ± 0.67
Hypothalamus1.89 ± 0.49
Insula1.41 ± 0.62
Limbic Lobe1.81 ± 0.7
Mesencephalon2 ± 0.65
Myelencephalon1.82 ± 0.74
Occipital Lobe2.2 ± 0.74
Parietal Lobe1.85 ± 0.86
Pontine Tegmentum1.85 ± 0.81
Striatum2.27 ± 0.75
Subthalamus2.05 ± 0.43
Temporal Lobe1.61 ± 0.74
Thalamus1.59 ± 0.67
White Matter2.09 ± 0.49
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Dnmt2CBCerebellum1.53
3.15
Dnmt2CTXCerebral cortex1.51
2.08
Dnmt2HIPHippocampal region0.92
1.48
Dnmt2HPFHippocampal formation0.73
1.28
Dnmt2HYHypothalamus0.09
0.18
Dnmt2LSXLateral septal complex0.09
0.08
Dnmt2MBMidbrain0.18
0.24
Dnmt2MYMedulla0.27
0.3
Dnmt2OLFOlfactory bulb0.79
1.51
Dnmt2PPons0.16
0.4
Dnmt2PALPallidum0.09
0.08
Dnmt2RHPRetrohippocampal region0.46
1.01
Dnmt2sAMYStriatum-like amygdalar nuclei0.1
0.09
Dnmt2STRStriatum0.53
0.84
Dnmt2STRdStriatum dorsal region0.79
1.27
Dnmt2STRvStriatum ventral region0.08
0.16
Dnmt2THThalamus0.85
1.11
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00080439 16 6 21 VLELYSGVGGMHHALR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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