AutismKB 2.0

Annotation Detail for DOM3Z


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Basic Information Top
Gene Symbol:DOM3Z ( DOM3L,NG6 )
Gene Full Name: dom-3 homolog Z (C. elegans)
Band: 6p21.3
Quick LinksEntrez ID:1797; OMIM: 605996; Uniprot ID:DOM3Z_HUMAN; ENSEMBL ID: ENSG00000204348; HGNC ID:
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus18 / 56401231
neonate1 / 3109732
infant2 / 2362084
juvenile0 / 555560 
adult54 / 193912127
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor5 / 9417853
cervical tumor2 / 3436658
chondrosarcoma3 / 8282336
colorectal tumor3 / 11424626
esophageal tumor0 / 172900 
gastrointestinal tumor2 / 11936916
germ cell tumor1 / 2638453
glioma2 / 10688318
head and neck tumor1 / 1363027
kidney tumor2 / 6895929
leukemia4 / 9584241
liver tumor5 / 9635951
lung tumor3 / 10312729
lymphoma5 / 7175569
non-neoplasia0 / 972500 
normal108 / 336030732
ovarian tumor1 / 7668213
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS8 / 12568063
prostate cancer2 / 10268019
retinoblastoma2 / 4635643
skin tumor3 / 12494924
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland5 / 33197150
ascites1 / 4001524
bladder2 / 2975767
blood7 / 12347856
bone1 / 7165513
bone marrow1 / 4880120
brain26 / 110098923
cervix2 / 4817141
connective tissue2 / 14925513
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye6 / 21105428
heart1 / 8962611
intestine4 / 23447217
kidney8 / 21177737
larynx0 / 241450 
liver8 / 20774338
lung8 / 33697423
lymph5 / 44270112
lymph node0 / 916100 
mammary gland5 / 15327132
mouth0 / 670520 
muscle2 / 10771518
nerve1 / 1576863
ovary2 / 10205119
pancreas1 / 2148124
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland3 / 16585180
placenta9 / 28082532
prostate4 / 18934521
salivary gland0 / 201550 
skin7 / 21057433
spleen5 / 5395292
stomach1 / 9661910
testis12 / 33044236
thymus1 / 8113112
thyroid1 / 4747321
tonsil1 / 1699958
trachea0 / 524130 
umbilical cord0 / 136800 
uterus7 / 23287830
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 215982_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts6.4
Adipocyte4.85
AdrenalCortex29.3
Adrenalgland8.2
Amygdala5.15
Appendix5
AtrioventricularNode3.75
BDCA4+_DentriticCells5.8
Bonemarrow4.8
BronchialEpithelialCells4.75
CD105+_Endothelial4.95
CD14+_Monocytes5.25
CD19+_BCells(neg._sel.)11.1
CD33+_Myeloid9.7
CD34+11.15
CD4+_Tcells13.2
CD56+_NKCells5.85
CD71+_EarlyErythroid5.45
CD8+_Tcells9.2
CardiacMyocytes6.2
Caudatenucleus4.45
Cerebellum4.7
CerebellumPeduncles5.75
CiliaryGanglion3.55
CingulateCortex5.15
Colorectaladenocarcinoma4.95
DorsalRootGanglion3.7
FetalThyroid5.35
Fetalbrain4.85
Fetalliver4.4
Fetallung4.7
GlobusPallidus3.6
Heart7.2
Hypothalamus5.55
Kidney4.05
Leukemia_chronicMyelogenousK-5624.55
Leukemia_promyelocytic-HL-604.35
Leukemialymphoblastic(MOLT-4)4.15
Liver6.55
Lung5.35
Lymphnode4.3
Lymphoma_burkitts(Daudi)6.35
Lymphoma_burkitts(Raji)6.85
MedullaOblongata4.45
OccipitalLobe4.45
OlfactoryBulb4.8
Ovary3.45
Pancreas3.95
PancreaticIslet5.15
ParietalLobe5.1
Pituitary6.15
Placenta5
Pons4.75
PrefrontalCortex5.85
Prostate5.9
Salivarygland3.95
SkeletalMuscle5.6
Skin3.7
SmoothMuscle5.45
Spinalcord5.7
SubthalamicNucleus4.4
SuperiorCervicalGanglion5.85
TemporalLobe4.5
Testis29.35
TestisGermCell30.35
TestisIntersitial29.15
TestisLeydigCell14.3
TestisSeminiferousTubule14.6
Thalamus5
Thymus4.05
Thyroid6.25
Tongue4.8
Tonsil4.8
Trachea4.25
TrigeminalGanglion4.75
Uterus4.05
UterusCorpus4.35
WholeBlood5.5
Wholebrain4.5
colon4.95
pineal_day7.3
pineal_night7.62
retina6.15
small_intestine4.75
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_13096_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.17 ± 0.35
Basal Forebrain5.45 ± 0.23
Basal Part of Pons5.99 ± 0.29
Cerebellar Cortex6.03 ± 0.31
Cerebellar Nuclei6.09 ± 0.33
Claustrum4.81 ± 0.75
Epithalamus5.95 ± 0.42
Frontal Lobe5.57 ± 0.44
Globus Pallidus5.1 ± 0.25
Hypothalamus5.9 ± 0.68
Insula5.62 ± 0.4
Limbic Lobe5.16 ± 0.58
Mesencephalon5.5 ± 0.45
Myelencephalon5.44 ± 0.52
Occipital Lobe5.32 ± 0.35
Parietal Lobe5.51 ± 0.52
Pontine Tegmentum5.41 ± 0.59
Striatum5.3 ± 0.41
Subthalamus5.67 ± 0.05
Temporal Lobe5.55 ± 0.41
Thalamus5.52 ± 0.44
White Matter5.4 ± 0.4
Mouse Brain ISH
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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