AutismKB 2.0

Annotation Detail for DPP4


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Basic Information Top
Gene Symbol:DPP4 ( ADABP,ADCP2,CD26,DPPIV,TP103 )
Gene Full Name: dipeptidyl-peptidase 4
Band: 2q24.2
Quick LinksEntrez ID:1803; OMIM: 102720; Uniprot ID:DPP4_HUMAN; ENSEMBL ID: ENSG00000197635; HGNC ID: 3009
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus26 / 56401246
neonate9 / 31097289
infant0 / 236200 
juvenile1 / 5555617
adult200 / 1939121103
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma6 / 8282372
colorectal tumor2 / 11424617
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor9 / 26384534
glioma1 / 1068839
head and neck tumor1 / 1363027
kidney tumor2 / 6895929
leukemia0 / 958420 
liver tumor3 / 9635931
lung tumor1 / 1031279
lymphoma0 / 717550 
non-neoplasia1 / 9725010
normal258 / 336030776
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer2 / 10268019
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor44 / 125191351
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue3 / 13106228
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood7 / 12347856
bone1 / 7165513
bone marrow0 / 488010 
brain9 / 11009898
cervix0 / 481710 
connective tissue19 / 149255127
ear0 / 162120 
embryonic tissue1 / 2157224
esophagus0 / 202090 
eye1 / 2110544
heart3 / 8962633
intestine14 / 23447259
kidney43 / 211777203
larynx0 / 241450 
liver6 / 20774328
lung7 / 33697420
lymph0 / 442700 
lymph node0 / 916100 
mammary gland2 / 15327113
mouth0 / 670520 
muscle7 / 10771564
nerve2 / 15768126
ovary0 / 1020510 
pancreas3 / 21481213
parathyroid14 / 20539681
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta102 / 280825363
prostate26 / 189345137
salivary gland3 / 20155148
skin17 / 21057480
spleen4 / 5395274
stomach4 / 9661941
testis11 / 33044233
thymus5 / 8113161
thyroid1 / 4747321
tonsil0 / 169990 
trachea11 / 52413209
umbilical cord1 / 1368073
uterus11 / 23287847
vascular5 / 5178096
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 203716_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts7.65
Adipocyte17.7
AdrenalCortex9.85
Adrenalgland17.6
Amygdala7.9
Appendix8.25
AtrioventricularNode5.85
BDCA4+_DentriticCells110.85
Bonemarrow7.65
BronchialEpithelialCells7.2
CD105+_Endothelial7.6
CD14+_Monocytes7.95
CD19+_BCells(neg._sel.)7.85
CD33+_Myeloid9.65
CD34+9.55
CD4+_Tcells98.55
CD56+_NKCells8.4
CD71+_EarlyErythroid7.3
CD8+_Tcells85.85
CardiacMyocytes34.5
Caudatenucleus6.75
Cerebellum9.15
CerebellumPeduncles8.75
CiliaryGanglion5.35
CingulateCortex16.25
Colorectaladenocarcinoma7.5
DorsalRootGanglion7.7
FetalThyroid7.25
Fetalbrain7.45
Fetalliver12.9
Fetallung6.85
GlobusPallidus6.35
Heart19.65
Hypothalamus10.5
Kidney28.45
Leukemia_chronicMyelogenousK-5626.8
Leukemia_promyelocytic-HL-606.6
Leukemialymphoblastic(MOLT-4)6
Liver10.65
Lung8.15
Lymphnode7.55
Lymphoma_burkitts(Daudi)9.7
Lymphoma_burkitts(Raji)10.6
MedullaOblongata8.8
OccipitalLobe8.4
OlfactoryBulb6.25
Ovary6.25
Pancreas8.6
PancreaticIslet8.3
ParietalLobe9.45
Pituitary8.8
Placenta26.7
Pons7.25
PrefrontalCortex9.4
Prostate30.05
Salivarygland93.2
SkeletalMuscle13.8
Skin6.3
SmoothMuscle629.1
Spinalcord8
SubthalamicNucleus13.95
SuperiorCervicalGanglion18.75
TemporalLobe6.85
Testis6.5
TestisGermCell6.35
TestisIntersitial7.35
TestisLeydigCell7.45
TestisSeminiferousTubule6.4
Thalamus7.85
Thymus5.95
Thyroid9.2
Tongue7.65
Tonsil7.3
Trachea9.7
TrigeminalGanglion8.05
Uterus6.05
UterusCorpus16.75
WholeBlood8.25
Wholebrain6.3
colon11.7
pineal_day8.92
pineal_night8.64
retina8.525
small_intestine17.45
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_16971_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.31 ± 0.86
Basal Forebrain2.78 ± 0.4
Basal Part of Pons2.81 ± 0.52
Cerebellar Cortex2.76 ± 0.74
Cerebellar Nuclei3.19 ± 0.71
Claustrum3.38 ± 0.54
Epithalamus2.62 ± 0.92
Frontal Lobe3.11 ± 0.74
Globus Pallidus2.69 ± 0.61
Hypothalamus2.94 ± 0.74
Insula2.43 ± 0.79
Limbic Lobe3.15 ± 0.71
Mesencephalon3.18 ± 0.83
Myelencephalon3.11 ± 0.75
Occipital Lobe3.67 ± 0.95
Parietal Lobe3.37 ± 0.67
Pontine Tegmentum3.02 ± 0.73
Striatum2.51 ± 0.98
Subthalamus3.22 ± 1.01
Temporal Lobe2.94 ± 0.69
Thalamus2.89 ± 0.79
White Matter2.4 ± 0.6
Mouse Brain ISH
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
DPP4_HUMAN_125 14 125 138 HSYTASYDIYDLNK PRIDE
DPP4_HUMAN_125 15 125 139 HSYTASYDIYDLNKR PRIDE
DPP4_HUMAN_163 12 163 174 LAYVWNNDIYVK PRIDE
DPP4_HUMAN_175 9 175 183 IEPNLPSYR PRIDE
DPP4_HUMAN_310 7 310 316 ISLQWLR PRIDE
DPP4_HUMAN_356 17 356 372 FRPSEPHFTLDGNSFYK PRIDE
DPP4_HUMAN_373 9 373 381 IISNEEGYR PRIDE
DPP4_HUMAN_40 10 40 49 KTYTLTDYLK PRIDE
DPP4_HUMAN_433 8 433 440 IQLSDYTK PRIDE
DPP4_HUMAN_441 12 441 452 VTCLSCELNPER PRIDE
DPP4_HUMAN_453 10 453 462 CQYYSVSFSK PRIDE
DPP4_HUMAN_492 10 492 501 VLEDNSALDK PRIDE
DPP4_HUMAN_502 10 502 511 MLQNVQMPSK PRIDE
DPP4_HUMAN_560 21 560 580 LNWATYLASTENIIVASFDGR PRIDE
DPP4_HUMAN_581 16 581 596 GSGYQGDKIMHAINRR PRIDE
DPP4_HUMAN_597 14 597 610 LGTFEVEDQIEAAR PRIDE
DPP4_HUMAN_670 15 670 684 YMGLPTPEDNLDHYR PRIDE
PAp00001015 10 649 658 CGIAVAPVSR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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