AutismKB 2.0

Annotation Detail for DPP6


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Basic Information Top
Gene Symbol:DPP6 ( DPPX,FLJ55680,MGC46605,VF2 )
Gene Full Name: dipeptidyl-peptidase 6
Band: 7q36.2
Quick LinksEntrez ID:1804; OMIM: 126141; Uniprot ID:DPP6_HUMAN; ENSEMBL ID: ENSG00000130226; HGNC ID: 3010
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus22 / 56401239
neonate0 / 310970 
infant5 / 23620211
juvenile1 / 5555617
adult37 / 193912119
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus1 / 5640121
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult0 / 19391210 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor6 / 26384522
glioma14 / 106883130
head and neck tumor2 / 13630214
kidney tumor2 / 6895929
leukemia1 / 9584210
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal111 / 336030733
ovarian tumor0 / 766820 
pancreatic tumor27 / 104616258
primitive neuroectodermal tumor of the CNS2 / 12568015
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor0 / 2638450 
glioma1 / 1068839
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal1 / 33603070 
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma2 / 4635643
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood1 / 1234788
bone0 / 716550 
bone marrow0 / 488010 
brain99 / 110098989
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye14 / 21105466
heart0 / 896260 
intestine1 / 2344724
kidney2 / 2117779
larynx2 / 2414582
liver0 / 2077430 
lung5 / 33697414
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas35 / 214812162
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland1 / 1658560
placenta1 / 2808253
prostate0 / 1893450 
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach1 / 9661910
testis8 / 33044224
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus2 / 2328788
vascular0 / 517800 
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain2 / 11009891
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye2 / 2110549
heart0 / 896260 
intestine0 / 2344720 
kidney0 / 2117770 
larynx0 / 241450 
liver0 / 2077430 
lung2 / 3369745
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate0 / 1893450 
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach0 / 966190 
testis0 / 3304420 
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 207789_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts4.35
Adipocyte3.4
AdrenalCortex3.55
Adrenalgland2.85
Amygdala82.3
Appendix3.45
AtrioventricularNode2.55
BDCA4+_DentriticCells3.85
Bonemarrow3.4
BronchialEpithelialCells3.4
CD105+_Endothelial3.5
CD14+_Monocytes3.7
CD19+_BCells(neg._sel.)3.7
CD33+_Myeloid4.5
CD34+4.45
CD4+_Tcells3.8
CD56+_NKCells4.2
CD71+_EarlyErythroid3.2
CD8+_Tcells3.35
CardiacMyocytes4.2
Caudatenucleus55.2
Cerebellum71.2
CerebellumPeduncles77.7
CiliaryGanglion2.35
CingulateCortex113.25
Colorectaladenocarcinoma3.4
DorsalRootGanglion2.6
FetalThyroid3.35
Fetalbrain7.55
Fetalliver2.95
Fetallung2.9
GlobusPallidus27.45
Heart4.35
Hypothalamus43.6
Kidney2.75
Leukemia_chronicMyelogenousK-5623.1
Leukemia_promyelocytic-HL-603.05
Leukemialymphoblastic(MOLT-4)2.8
Liver4.45
Lung3.85
Lymphnode2.95
Lymphoma_burkitts(Daudi)4.35
Lymphoma_burkitts(Raji)4.75
MedullaOblongata70.1
OccipitalLobe60.7
OlfactoryBulb2.75
Ovary2.25
Pancreas2.75
PancreaticIslet11.55
ParietalLobe34.3
Pituitary4.05
Placenta3.6
Pons26
PrefrontalCortex80.35
Prostate4.1
Salivarygland2.7
SkeletalMuscle3.8
Skin2.6
SmoothMuscle3.9
Spinalcord4.95
SubthalamicNucleus33.05
SuperiorCervicalGanglion3.85
TemporalLobe27.05
Testis3
TestisGermCell7
TestisIntersitial2.95
TestisLeydigCell3.35
TestisSeminiferousTubule3.2
Thalamus129.45
Thymus2.75
Thyroid5.5
Tongue3.3
Tonsil3.3
Trachea2.9
TrigeminalGanglion3.4
Uterus23.75
UterusCorpus3.05
WholeBlood3.75
Wholebrain59
colon3.45
pineal_day50.1
pineal_night47
retina10.325
small_intestine3.35
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_32_P175900
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.54 ± 0.63
Basal Forebrain4.64 ± 0.33
Basal Part of Pons5.31 ± 0.34
Cerebellar Cortex5.24 ± 0.45
Cerebellar Nuclei4.67 ± 0.53
Claustrum3.92 ± 0.81
Epithalamus4.85 ± 0.67
Frontal Lobe4.81 ± 0.57
Globus Pallidus4.49 ± 0.59
Hypothalamus4.18 ± 0.43
Insula4.73 ± 0.61
Limbic Lobe4.88 ± 0.79
Mesencephalon4.79 ± 0.71
Myelencephalon4.78 ± 0.61
Occipital Lobe5.19 ± 0.46
Parietal Lobe4.92 ± 0.55
Pontine Tegmentum4.65 ± 0.53
Striatum4.81 ± 0.5
Subthalamus4.16 ± 1.02
Temporal Lobe4.86 ± 0.53
Thalamus4.76 ± 0.56
White Matter5.02 ± 0.4
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Dpp6CBCerebellum100
100
Dpp6CTXCerebral cortex100
100
Dpp6HIPHippocampal region100
100
Dpp6HPFHippocampal formation100
100
Dpp6HYHypothalamus100
100
Dpp6LSXLateral septal complex100
100
Dpp6MBMidbrain100
100
Dpp6MYMedulla100
100
Dpp6OLFOlfactory bulb100
100
Dpp6PPons100
100
Dpp6PALPallidum100
100
Dpp6RHPRetrohippocampal region100
100
Dpp6sAMYStriatum-like amygdalar nuclei100
100
Dpp6STRStriatum100
100
Dpp6STRdStriatum dorsal region100
100
Dpp6STRvStriatum ventral region100
100
Dpp6THThalamus100
100
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00077533 11 776 786 SIINFFVECFR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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